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Q9NP04

- Q9NP04_HUMAN

UniProt

Q9NP04 - Q9NP04_HUMAN

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Protein
Submitted name:

Folate receptor alpha isoform

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. folic acid binding Source: Ensembl
  2. folic acid transporter activity Source: Ensembl

GO - Biological processi

  1. folic acid metabolic process Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Folate receptor alpha isoformImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. anchored component of plasma membrane Source: Ensembl
  2. brush border membrane Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9NP04.
ExpressionAtlasiQ9NP04. baseline and differential.

Interactioni

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG039612.

Family and domain databases

InterProiIPR004269. Folate_rcpt.
IPR018143. Folate_rcpt-like.
[Graphical view]
PANTHERiPTHR10517. PTHR10517. 1 hit.
PfamiPF03024. Folate_rec. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9NP04 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQRMTTQLL LLLVWVAVVG EAQTRIAWAR TELLNVCMNA KHHKEKPGPE
60 70 80 90 100
DKLHEQCRPW RKNACCSTNT SQEAHKDVSY LYRFNWNHCG EMAPACKRHF

IQDTC
Length:105
Mass (Da):12,225
Last modified:October 1, 2000 - v1
Checksum:iB30DE5868EFB2CE9
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei105 – 1051Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S73490 mRNA. Translation: AAB31700.1.
UniGeneiHs.73769.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
S73490 mRNA. Translation: AAB31700.1 .
UniGenei Hs.73769.

3D structure databases

ModBasei Search...
MobiDBi Search...

Chemistry

BindingDBi Q9NP04.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG039612.

Gene expression databases

Bgeei Q9NP04.
ExpressionAtlasi Q9NP04. baseline and differential.

Family and domain databases

InterProi IPR004269. Folate_rcpt.
IPR018143. Folate_rcpt-like.
[Graphical view ]
PANTHERi PTHR10517. PTHR10517. 1 hit.
Pfami PF03024. Folate_rec. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Selective expression of the high-affinity isoform of the folate receptor (FR-alpha) in the human placental syncytiotrophoblast and choriocarcinoma cells."
    Prasad P.D., Ramamoorthy S., Moe A.J., Smith C.H., Leibach F.H., Ganapathy V.
    Biochim. Biophys. Acta 1223:71-75(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ9NP04_HUMAN
AccessioniPrimary (citable) accession number: Q9NP04
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.