ID   DNJC4_HUMAN             Reviewed;         241 AA.
AC   Q9NNZ3; O14716;
DT   18-OCT-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-JAN-2012, entry version 92.
DE   RecName: Full=DnaJ homolog subfamily C member 4;
DE   AltName: Full=DnaJ-like protein HSPF2;
DE   AltName: Full=Multiple endocrine neoplasia type 1 candidate protein number 18;
GN   Name=DNAJC4; Synonyms=HSPF2, MCG18;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   MEDLINE=98139904; PubMed=9473517; DOI=10.1006/bbrc.1997.8091;
RA   Silins G., Grimmond S., Hayward N.;
RT   "Characterisation of a new human and murine member of the DnaJ family
RT   of proteins.";
RL   Biochem. Biophys. Res. Commun. 243:273-276(1998).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain, and Placenta;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [3]
RP   PARTIAL NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Placenta;
RA   Lloyd S.E., Thakker R.V.;
RT   "Identification and characterisation of a novel human Dnaj gene,
RT   HSPF2, mapping to chromosome 11q13.";
RL   Submitted (JUL-1997) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Contains 1 J domain.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB82426.1; Type=Miscellaneous discrepancy; Note=Several sequence rearrangements;
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DR   EMBL; AF036874; AAF97845.1; -; mRNA.
DR   EMBL; BC044584; AAH44584.1; -; mRNA.
DR   EMBL; BC057849; AAH57849.1; -; mRNA.
DR   EMBL; AF012106; AAB82426.1; ALT_SEQ; mRNA.
DR   IPI; IPI00328890; -.
DR   PIR; JE0169; JE0169.
DR   RefSeq; NP_005519.2; NM_005528.3.
DR   UniGene; Hs.172847; -.
DR   ProteinModelPortal; Q9NNZ3; -.
DR   SMR; Q9NNZ3; 33-99.
DR   IntAct; Q9NNZ3; 1.
DR   STRING; Q9NNZ3; -.
DR   PhosphoSite; Q9NNZ3; -.
DR   DMDM; 18203312; -.
DR   PRIDE; Q9NNZ3; -.
DR   Ensembl; ENST00000321460; ENSP00000320548; ENSG00000110011.
DR   Ensembl; ENST00000321685; ENSP00000396896; ENSG00000110011.
DR   GeneID; 3338; -.
DR   KEGG; hsa:3338; -.
DR   UCSC; uc001nys.1; human.
DR   CTD; 3338; -.
DR   GeneCards; GC11P063997; -.
DR   H-InvDB; HIX0201666; -.
DR   HGNC; HGNC:5271; DNAJC4.
DR   HPA; HPA011947; -.
DR   MIM; 604189; gene.
DR   neXtProt; NX_Q9NNZ3; -.
DR   PharmGKB; PA27421; -.
DR   eggNOG; prNOG16256; -.
DR   GeneTree; ENSGT00510000048574; -.
DR   HOGENOM; HBG714808; -.
DR   HOVERGEN; HBG051375; -.
DR   InParanoid; Q9NNZ3; -.
DR   OMA; RRSYDDQ; -.
DR   OrthoDB; EOG432109; -.
DR   PhylomeDB; Q9NNZ3; -.
DR   NextBio; 13212; -.
DR   ArrayExpress; Q9NNZ3; -.
DR   Bgee; Q9NNZ3; -.
DR   CleanEx; HS_DNAJC4; -.
DR   Genevestigator; Q9NNZ3; -.
DR   GermOnline; ENSG00000110011; Homo sapiens.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005624; C:membrane fraction; TAS:ProtInc.
DR   GO; GO:0031072; F:heat shock protein binding; IEA:InterPro.
DR   GO; GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
DR   GO; GO:0006457; P:protein folding; NAS:UniProtKB.
DR   GO; GO:0006986; P:response to unfolded protein; TAS:ProtInc.
DR   InterPro; IPR001623; DnaJ_N.
DR   InterPro; IPR003095; Hsp_DnaJ.
DR   Gene3D; G3DSA:1.10.287.110; DnaJ_N; 1.
DR   KO; K09524; -.
DR   Pfam; PF00226; DnaJ; 1.
DR   PRINTS; PR00625; JDOMAIN.
DR   SMART; SM00271; DnaJ; 1.
DR   SUPFAM; SSF46565; DnaJ_N; 1.
DR   PROSITE; PS00636; DNAJ_1; FALSE_NEG.
DR   PROSITE; PS50076; DNAJ_2; 1.
PE   2: Evidence at transcript level;
KW   Chaperone; Complete proteome; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN         1    241       DnaJ homolog subfamily C member 4.
FT                                /FTId=PRO_0000071049.
FT   TRANSMEM    156    175       Helical; (Potential).
FT   DOMAIN       34     99       J.
SQ   SEQUENCE   241 AA;  27593 MW;  EA186D2FA6C2E179 CRC64;
     MPPLLPLRLC RLWPRNPPSR LLGAAAGQRS RPSTYYELLG VHPGASTEEV KRAFFSKSKE
     LHPDRDPGNP SLHSRFVELS EAYRVLSREQ SRRSYDDQLR SGSPPKSPRT TVHDKSAHQT
     HSSWTPPNAQ YWSQFHSVRP QGPQLRQQQH KQNKQVLGYC LLLMLAGMGL HYIAFRKVKQ
     MHLNFMDEKD RIITAFYNEA RARARANRGI LQQERQRLGQ RQPPPSEPTQ GPEIVPRGAG
     P
//