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Protein
Submitted name:

Glutathione S-transferase 2

Gene
N/A
Organism
Heligmosomoides polygyrus (Parasitic roundworm)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

TransferaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
Glutathione S-transferase 2Imported
OrganismiHeligmosomoides polygyrus (Parasitic roundworm)Imported
Taxonomic identifieri6339 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaStrongylidaTrichostrongyloideaHeligmosomatidaeHeligmosomoides

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TW9X-ray1.71A/B/C/D/E/F/G/H1-204[»]
ProteinModelPortaliQ9NJQ6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9NJQ6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini1 – 7777GST N-terminalInterPro annotationAdd
BLAST
Domaini79 – 204126GST C-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the GST superfamily.UniRule annotation
Contains GST C-terminal domain.SAAS annotation
Contains GST N-terminal domain.SAAS annotation

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF14497. GST_C_3. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9NJQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
HYKLTYFNGR GAGECARQIF ALADQKYEDV RLTQETFAPL KATFPFGQVP
60 70 80 90 100
VLEVDGQQLA QSQAICRYLA KTFGFAGATP FESALIDSPA DAYTDYRAEM
110 120 130 140 150
KTYYYMALGF MTGDVDKLKT DVLLPARTKF LGFITKFPKK NSSGFLVGDK
160 170 180 190 200
ISWVDLLVAE HVADMTNRVP EYIEGFPEVK AHMERIQQTP RIKKWIETRP

ETPF
Length:204
Mass (Da):23,159
Last modified:October 1, 2000 - v1
Checksum:iF3D61378537DD6ED
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF128959 mRNA. Translation: AAF36480.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF128959 mRNA. Translation: AAF36480.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1TW9X-ray1.71A/B/C/D/E/F/G/H1-204[»]
ProteinModelPortaliQ9NJQ6.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiQ9NJQ6.

Family and domain databases

Gene3Di1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProiIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR004046. GST_C.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamiPF14497. GST_C_3. 1 hit.
PF02798. GST_N. 1 hit.
[Graphical view]
SUPFAMiSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEiPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Proposed Crystal Structure of Heligmosomoides polygyrus GST2."
    Campbell A.M., Brophy P.M., Teesdale-Spittle P., Barrett J.
    Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "Crystal structure of a new class of glutathione transferase from the model human hookworm nematode Heligmosomoides polygyrus."
    Schuller D.J., Liu Q., Kriksunov I.A., Campbell A.M., Barrett J., Brophy P.M., Hao Q.
    Proteins 61:1024-1031(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.71 ANGSTROMS).

Entry informationi

Entry nameiQ9NJQ6_HELPZ
AccessioniPrimary (citable) accession number: Q9NJQ6
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.