Unreviewed, UniProtKB/TrEMBL Q9NJH7 (Q9NJH7_DROME)

Names and origin

Protein names

Submitted name:
    IF2 protein EMBL AAF36532.1

Gene names

Name:	eIF5B FlyBase FBgn0026259
Synonyms:	cIF2 FlyBase FBgn0026259
ORF Names:	CG10840 FlyBase FBgn0026259

Organism

Drosophila melanogaster (Fruit fly) [Complete proteome] EMBL AAF36532.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1144 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Ligand	GTP-binding RuleBase RU003312V0 Nucleotide-binding
Technical term	Complete proteome
Gene Ontology (GO)
Molecular function	DEAD/H-box RNA helicase binding Traceable author statement. Source: FlyBase GTP binding Inferred from electronic annotation. Source: InterPro GTPase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9NJH7-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: A035415A3762CF0C	FASTA	1,144	127,204
	10 20 30 40 50 60 MVKAKKGKKE ILTKVEGGSS VDEISDVDSD QLSLNNKQNH ALKGNQAGDD DVKAVTKGVK 70 80 90 100 110 120 KLNVKGKGKA GKNDDSDEEE VVPAKGKASK KSAFELLMDD DEQDEPAAQE SQSEEEEKVV 130 140 150 160 170 180 VSKPQKNEKK GKKAKRKGKD DDDEDLDKVL AELQAEYAGE AAPAATTVVS PEELADEFSK 190 200 210 220 230 240 KKKNKKQAKQ AAVAENAGED EASDDEEGGS TVKSAAQKKK EKKERQKREA ALAKQKAATE 250 260 270 280 290 300 PKPKPVEKPA PEPEPVATEE VQPAAEEEEE KSSKNKKKGK KDKKAEPEEE KKDAKKKGMS 310 320 330 340 350 360 ASMVAAMQEQ LRKRKEEEER LEREEAERIR LEDEREEARL EAVRLEAERK EKKKQREAER 370 380 390 400 410 420 KARLKAEGKL LTKKQKEDRA RAQALLESLK AQGLEIPDPN DKRPTRPGTR IRPNKKKGPK 430 440 450 460 470 480 EEAAEEEAKA AEAEAQSAAA AAAAAAAEKA EEERVKESWD ATDSEAEPEP EEETSQATNN 490 500 510 520 530 540 GKTEAAEEEN EDTDDDEDDD DDEDDSDDSD GDSDDSREVS VLANDPESRR LRAEARILKR 550 560 570 580 590 600 QAEAEKKRST DELRAGVVCV LGHVDTGKTK ILDKLRRTHV QDSEAGGITQ QIGATNVPIE 610 620 630 640 650 660 AIKEQTKYVK AAAGFEHRLP GLLIIDTPGH ESFSNLRNRG SSLCDIAILV VDIMHGLEPQ 670 680 690 700 710 720 TIESIQLLKK KKCPFIVALN KIDRLYDWKQ LARRDVRDVL KEQQSNTQLE FQQRTKDVIL 730 740 750 760 770 780 QFAEQGLNAA LFYENTDPKT YISLVPTSAI SGEGMGNLLF MIADFCQNML AKRLMYSEEL 790 800 810 820 830 840 QATVLEVKAL PGLGTTIDAI LINGKLREGQ TMVVAGTDGP IVTQIRSLLM PQPMKELRVK 850 860 870 880 890 900 NAYVEYKEVK AAQGVKIAAK DLEKAIAGIN LLIAHKPDEV EICTEEVARE LKSALSHIKL 910 920 930 940 950 960 AQTGVHVQAS TLGSLEALLE FLRTSKIPYS AIRIGPVVKR DVMKASTMLE HEAQYATILA 970 980 990 1000 1010 1020 FDVKIEREAQ EMADSLGVKI FQADIIYHLF DKFTAYREEL KQKKREEFRS VAVFPCKLRI 1030 1040 1050 1060 1070 1080 LPQFVFNSRD PIVMGVMVEN GIVKVGTPIC VPSKEFVDIG IVTSIESNHK QIEFARKGQE 1090 1100 1110 1120 1130 1140 ICVKIDPIPG ESPKMFGRHF EADDMLISKI SRQSIDACKD YFRDDLIKAD WALMVELKKL FEIL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"VASA mediates translation through interaction with a Drosophila yIF2 homolog." Carrera P., Johnstone O., Nakamura A., Casanova J., Jackle H., Lasko P. Mol. Cell 5:181-187(2000) [PubMed: 10678180] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"An integrated chemical, mass spectrometric and computational strategy for (quantitative) phosphoproteomics: application to Drosophila melanogaster Kc167 cells." Bodenmiller B., Mueller L.N., Pedrioli P.G.A., Pflieger D., Juenger M.A., Eng J.K., Aebersold R., Tao W.A. Mol. Biosyst. 3:275-286(2007) [PubMed: 17372656] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.
[3]	"Phosphoproteome analysis of Drosophila melanogaster embryos." Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P. J. Proteome Res. 7:1675-1682(2008) [PubMed: 18327897] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS], MASS SPECTROMETRY.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AF143207 mRNA. Translation: AAF36532.1.
3D structure databases
HSSP	HSSP built from PDB template 1G7S based on UniProtKB O26359.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9NJH7. 1 interaction.
Proteomic databases
PRIDE	Q9NJH7.
Genome annotation databases
Ensembl	FBgn0026259. Drosophila melanogaster. [Contig view]
Organism-specific databases
FlyBase	FBgn0026259. eIF5B.
Gene expression databases
ArrayExpress	Q9NJH7.
Family and domain databases
InterPro	IPR015760. aIF-2. IPR000795. ProtSyn_GTP_bd. IPR005225. Small_GTP_bd. IPR004161. Transl_elong_EFTu/EF1A_2. [Graphical view]
PANTHER	PTHR23115:SF41. aIF-2. 1 hit.
Pfam	PF00009. GTP_EFTU. 1 hit. PF03144. GTP_EFTU_D2. 1 hit. [Graphical view]
PRINTS	PR00315. ELONGATNFCT.
TIGRFAMs	TIGR00231. small_GTP. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q9NJH7_DROME

Accession

Primary (citable) accession number: Q9NJH7

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)