Q9NHP2 (Q9NHP2_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Plenty of SH3s EMBL AAF37265.1

Gene names

Name:	POSH EMBL AAF37265.1
ORF Names:	CG4909 FlyBase FBgn0040294

Organism

Drosophila melanogaster (Fruit fly) EMBL AAF37265.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	838 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 4 SH3 domains. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338 Zinc-finger RuleBase RU000353
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	determination of adult lifespan Inferred from mutant phenotype. Source: FlyBase negative regulation of cell death Inferred from mutant phenotype. Source: FlyBase
Molecular function	receptor signaling complex scaffold activity Non-traceable author statement. Source: FlyBase ubiquitin-protein ligase activity Inferred from direct assay. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9NHP2 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 2D0C36CAF93C6397	FASTA	838	92,010
	10 20 30 40 50 60 MDEHTLNDLL ECSVCLERLD TTSKVLPCQH TFCRKCLQDI VASQHKLRCP ECRILVSCKI 70 80 90 100 110 120 DELPPNVLLM RILEGMKQNA AAGKGEEKGE ETETQPERAK PQPPAESVAP PDNQLLQLQS 130 140 150 160 170 180 HQQSHQPARH KQRRFLLPHA YALFDFASGE ATDLKFKKGD LILIKHRIDN NWFVGQANGQ 190 200 210 220 230 240 EGTFPINYVK VSVPLPMPQC IAMYDFKMGP NDEEGCLEFK KSTVIQVMRR VDHNWAEGRI 250 260 270 280 290 300 GQTIGIFPIA FVELNAAAKK LLDSGLHTHP LCHPPKQQGQ RALPPVPVID PTVVTESSSG 310 320 330 340 350 360 SSNSTPGSSN SSSTSSSNNC SPNHQISLPN TPQHVVASGS ASVRFRDKGA KEKRHSLNAL 370 380 390 400 410 420 LGGGAPLSLL QTNRHSAEIL SLPHELSRLE VSSSTALKPT SAPQTSRVLK TTVQQQMQPN 430 440 450 460 470 480 LPWGYLALFP YKPRQTDELE LKKGCVYIVT ERCVDGWFKG KNWLDITGVF PGNYLTPLRA 490 500 510 520 530 540 RDQQQLMHQW KYVPQNADAQ MAQVQQHPVA PDVRLNNMLS MQPPDLPPRQ QQATATTTSC 550 560 570 580 590 600 SVWSKPVEAL FSRKSEPKPD TATASTTSSS SSGAVGLMRR LTHMKTRSKS PGASLQQVPK 610 620 630 640 650 660 EAISTNVEFT TNPSAKLHPV HVRSGSCPSQ LQHSQPLNET PAAKTAAQQQ QFLPKQLPSA 670 680 690 700 710 720 STNSVSYGSQ RVKGSKERPH LICARQSLDA ATFRSMYNNA ASPPPPTTSV APAVYAGGQQ 730 740 750 760 770 780 QVIPGGGAQS QLHANMIIAP SHRKSHSLDA SHVLSPSSNM ITEAAIKASA TTKSPYCTRE 790 800 810 820 830 SRFRCIVPYP PNSDIELELH LGDIIYVQRK QKNGWYKGTH ARTHKTGLFP ASFVEPDC

References

[1]	"Molecular cloning and characterization of Drosophila POSH." Seong K., Aigaki T. Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF220364 mRNA. Translation: AAF37265.1.
3D structure databases
HSSP	HSSP built from PDB template 1SEM based on UniProtKB P29355.
ProteinModelPortal	Q9NHP2.
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-2568260.
STRING	Q9NHP2.
Proteomic databases
PRIDE	Q9NHP2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0040294. POSH.
Phylogenomic databases
eggNOG	inNOG05929.
GeneTree	EMGT00050000003932.
InParanoid	Q9NHP2.
Gene expression databases
ArrayExpress	Q9NHP2.
Bgee	Q9NHP2.
Family and domain databases
InterPro	IPR000108. p67phox. IPR001452. SH3_domain. IPR018957. Znf_C3HC4_RING-type. IPR001841. Znf_RING. IPR013083. Znf_RING/FYVE/PHD. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 1 hit.
Pfam	PF00018. SH3_1. 3 hits. PF00097. zf-C3HC4. 1 hit. [Graphical view]
PRINTS	PR00499. P67PHOX. PR00452. SH3DOMAIN.
SMART	SM00184. RING. 1 hit. SM00326. SH3. 4 hits. [Graphical view]
SUPFAM	SSF50044. SH3. 4 hits.
PROSITE	PS50002. SH3. 4 hits. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NHP2_DROME

Accession

Primary (citable) accession number: Q9NHP2

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	November 16, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)