Q9NH88 (Q9NH88_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Partner of Inscuteable EMBL AAF36967.1

Gene names

Name:	raps FlyBase FBgn0040080
Synonyms:	pins EMBL AAF36967.1
ORF Names:	CG5692 FlyBase FBgn0040080

Organism

Drosophila melanogaster (Fruit fly) EMBL AAF36967.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	658 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Repeat RuleBase RU003537 TPR repeat RuleBase RU003339 SAAS SAAS001440
Gene Ontology (GO)
Biological process	asymmetric cell division Inferred from direct assay. Source: FlyBase asymmetric neuroblast division Inferred from mutant phenotype. Source: FlyBase asymmetric protein localization involved in cell fate determination Traceable author statement. Source: FlyBase basal protein localization Traceable author statement. Source: FlyBase establishment of mitotic spindle orientation Inferred from mutant phenotype. Source: FlyBase maintenance of protein location Non-traceable author statement. Source: FlyBase neuroblast fate determination Traceable author statement. Source: FlyBase signal transduction Inferred from electronic annotation. Source: InterPro
Cellular component	apical cortex Inferred from direct assay. Source: UniProtKB
Molecular function	GDP-dissociation inhibitor activity Inferred from direct assay. Source: UniProtKB GTPase activator activity Inferred from electronic annotation. Source: InterPro protein binding Inferred from physical interaction. Source: UniProtKB
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9NH88 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: A23E132F9ECDA8DF	FASTA	658	71,467
	10 20 30 40 50 60 MSSLSASAEN VSSLGLGSGG GGTNSHDGNS QQGSGSDGGS SMCLELALEG ERLCNAGDCR 70 80 90 100 110 120 AGVAFFQAAI QAGTEDLRTL SAIYSQLGNA YFYLGDYNKA MQYHKHDLTL AKSMNDRLGE 130 140 150 160 170 180 AKSSGNLGNT LKVMGRFDEA AICCERHLTL ARQLGDRLSE GRALYNLGNV YHAKGKHLGQ 190 200 210 220 230 240 RNPGKFGDDV KEALTRAVEF YQENLKLMRD LGDRGAQGRA CGNLGNTYYL LGDFQAAIEH 250 260 270 280 290 300 HQERLRIARE FGDRAAERRA NSNLGNSHIF LGQFEDAAEH YKRTLALAVE LGEREVEAQS 310 320 330 340 350 360 CYSLGNTYTL LHEFNTAIEY HNRHLAIAQE LGDRIGEARA CWSLGNAHSA IGGHERALKY 370 380 390 400 410 420 AEQHLQLAKE LHDPVGESTA RVNISDLRKL LGMPDSEPSP TEEEARSTAS DHSASGNQSD 430 440 450 460 470 480 GSENSQGRMV RVRRQSMEQL DLIKITPDGK RMQEEKLRAQ ATRKAKDDDF FEMLSRSQSK 490 500 510 520 530 540 RMDDQRCSIK VNPAGAPAVA TGATRKPLVQ QNSLFVDPTN LPGLKSPSSA IPSAIGHGPL 550 560 570 580 590 600 ARSATTTQQP DDDFLDMLMR CQGSRLEEQR SELPRPNVTM DAEAEAPPRS VPEAAVPGAP 610 620 630 640 650 RGQTGRGATV PDEDFFSLIM KVQSGRMEDQ RASIPFRNAN NNNNSRSNNN GSAGGAGK

References

[1]	"Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localization." Yu F., Morin X., Cai Y., Yang X., Chia W. Cell 100:399-409(2000) [PubMed: 10693757] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF230071 mRNA. Translation: AAF36967.1.
3D structure databases
ProteinModelPortal	Q9NH88.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9NH88. 4 interactions.
STRING	Q9NH88.
Proteomic databases
PRIDE	Q9NH88.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0040080. raps.
Phylogenomic databases
InParanoid	Q9NH88.
Gene expression databases
ArrayExpress	Q9NH88.
Bgee	Q9NH88.
Family and domain databases
InterPro	IPR003109. GoLoco_motif. IPR001440. TPR-1. IPR013026. TPR-contain. IPR011990. TPR-like_helical. IPR019734. TPR_repeat. [Graphical view]
Gene3D	G3DSA:1.25.40.10. TPR-like_helical. 4 hits.
Pfam	PF02188. GoLoco. 3 hits. PF00515. TPR_1. 1 hit. [Graphical view]
SMART	SM00390. GoLoco. 3 hits. SM00028. TPR. 7 hits. [Graphical view]
PROSITE	PS50877. GOLOCO. 3 hits. PS50005. TPR. 5 hits. PS50293. TPR_REGION. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NH88_DROME

Accession

Primary (citable) accession number: Q9NH88

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	November 16, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)