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Q9NH75 (VA4_SOLGE) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Venom allergen 4
Alternative name(s):
Venom allergen IV
Allergen=Sol g 4
OrganismSolenopsis geminata (Tropical fire ant)
Taxonomic identifier121131 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaFormicidaeMyrmicinaeSolenopsis

Protein attributes

Sequence length137 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Monomer By similarity.

Subcellular location

Secreted.

Tissue specificity

Expressed by the venom gland.

Allergenic properties

Causes an allergic reaction in human. The most common cause of insect venom allergy in the southeastern United States is the imported fire ant.

Sequence similarities

Belongs to the ant venom allergen 2/4 family.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   DomainSignal
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 By similarity
Chain20 – 137118Venom allergen 4
PRO_0000022647

Natural variations

Natural variant281M → V in Sol g 4.02.
Natural variant331E → K in Sol g 4.02.
Natural variant1231L → R in Sol g 4.02.

Sequences

Sequence LengthMass (Da)Tools
Q9NH75 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: F888BF6D11CCA082

FASTA13715,667
        10         20         30         40         50         60 
MKTFVLVSCL LVFTQIIYAV DIKELKIMNR ILEKCIRTVP KGENDPINPL KNVNVLYCAF 

        70         80         90        100        110        120 
SKRGIFTPKG VNTKQYINYC EKTIINPADI KQCKKLISKC IKKVYDRPGP IIERSKNLLS 

       130 
CVLKKGVLEL TVYGKKK 

« Hide

References

[1]"Allergens from tropical fire ant venom."
Schmidt M., Hoffman D.R.
Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Venom gland.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF230383 mRNA. Translation: AAF65312.1.
AF230384 mRNA. Translation: AAF65313.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome3479. Sol g 4.0101.
3480. Sol g 4.0201.
629. Sol g 4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR020181. Ant_venom_allergen_Sol_i_2/4.
IPR023316. PBP_GOBP_dom.
[Graphical view]
ProDomPD031252. Ant_venom_allergen_Sol_i_2/4. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF47565. SSF47565. 1 hit.
ProtoNetSearch...

Entry information

Entry nameVA4_SOLGE
AccessionPrimary (citable) accession number: Q9NH75
Secondary accession number(s): Q9NH74
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: October 1, 2000
Last modified: October 16, 2013
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries