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Q9NH75

- VA4_SOLGE

UniProt

Q9NH75 - VA4_SOLGE

Protein

Venom allergen 4

Gene
N/A
Organism
Solenopsis geminata (Tropical fire ant)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    Venom allergen 4
    Alternative name(s):
    Venom allergen IV
    Allergen: Sol g 4
    OrganismiSolenopsis geminata (Tropical fire ant)
    Taxonomic identifieri121131 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaFormicidaeMyrmicinaeSolenopsis

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    Pathology & Biotechi

    Allergenic propertiesi

    Causes an allergic reaction in human. The most common cause of insect venom allergy in the southeastern United States is the imported fire ant.

    Keywords - Diseasei

    Allergen

    Protein family/group databases

    Allergomei3479. Sol g 4.0101.
    3480. Sol g 4.0201.
    629. Sol g 4.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 1919By similarityAdd
    BLAST
    Chaini20 – 137118Venom allergen 4PRO_0000022647Add
    BLAST

    Expressioni

    Tissue specificityi

    Expressed by the venom gland.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ant venom allergen 2/4 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    InterProiIPR020181. Ant_venom_allergen_Sol_i_2/4.
    IPR023316. PBP_GOBP_dom.
    [Graphical view]
    ProDomiPD031252. Ant_venom_allergen_Sol_i_2/4. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF47565. SSF47565. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q9NH75-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKTFVLVSCL LVFTQIIYAV DIKELKIMNR ILEKCIRTVP KGENDPINPL    50
    KNVNVLYCAF SKRGIFTPKG VNTKQYINYC EKTIINPADI KQCKKLISKC 100
    IKKVYDRPGP IIERSKNLLS CVLKKGVLEL TVYGKKK 137
    Length:137
    Mass (Da):15,667
    Last modified:October 1, 2000 - v1
    Checksum:iF888BF6D11CCA082
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti28 – 281M → V in Sol g 4.02.
    Natural varianti33 – 331E → K in Sol g 4.02.
    Natural varianti123 – 1231L → R in Sol g 4.02.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF230383 mRNA. Translation: AAF65312.1.
    AF230384 mRNA. Translation: AAF65313.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF230383 mRNA. Translation: AAF65312.1 .
    AF230384 mRNA. Translation: AAF65313.1 .

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    Allergomei 3479. Sol g 4.0101.
    3480. Sol g 4.0201.
    629. Sol g 4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR020181. Ant_venom_allergen_Sol_i_2/4.
    IPR023316. PBP_GOBP_dom.
    [Graphical view ]
    ProDomi PD031252. Ant_venom_allergen_Sol_i_2/4. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF47565. SSF47565. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Allergens from tropical fire ant venom."
      Schmidt M., Hoffman D.R.
      Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Venom gland.

    Entry informationi

    Entry nameiVA4_SOLGE
    AccessioniPrimary (citable) accession number: Q9NH75
    Secondary accession number(s): Q9NH74
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 20, 2001
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. Allergens
      Nomenclature of allergens and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3