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Protein

Venom allergen 4

Gene
N/A
Organism
Solenopsis geminata (Tropical fire ant)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Venom allergen 4
Alternative name(s):
Venom allergen IV
Allergen: Sol g 4
OrganismiSolenopsis geminata (Tropical fire ant)
Taxonomic identifieri121131 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaHymenopteraApocritaAculeataFormicoideaFormicidaeMyrmicinaeSolenopsis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. The most common cause of insect venom allergy in the southeastern United States is the imported fire ant.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3479 Sol g 4.0101
3480 Sol g 4.0201
629 Sol g 4

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19By similarityAdd BLAST19
ChainiPRO_000002264720 – 137Venom allergen 4Add BLAST118

Proteomic databases

PRIDEiQ9NH75

Expressioni

Tissue specificityi

Expressed by the venom gland.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

SMRiQ9NH75
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ant venom allergen 2/4 family.Curated

Keywords - Domaini

Signal

Family and domain databases

CDDicd12800 Sol_i_2, 1 hit
Gene3Di1.10.238.190, 1 hit
InterProiView protein in InterPro
IPR020181 Ant_venom_allergen_Sol_i_2/4
IPR038211 Ant_venon_allerg_soli_2/4_sf
IPR036728 PBP_GOBP_sf
ProDomiView protein in ProDom or Entries sharing at least one domain
PD031252 Ant_venom_allergen_Sol_i_2/4, 1 hit
SUPFAMiSSF47565 SSF47565, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9NH75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFVLVSCL LVFTQIIYAV DIKELKIMNR ILEKCIRTVP KGENDPINPL
60 70 80 90 100
KNVNVLYCAF SKRGIFTPKG VNTKQYINYC EKTIINPADI KQCKKLISKC
110 120 130
IKKVYDRPGP IIERSKNLLS CVLKKGVLEL TVYGKKK
Length:137
Mass (Da):15,667
Last modified:October 1, 2000 - v1
Checksum:iF888BF6D11CCA082
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti28M → V in Sol g 4.02. 1
Natural varianti33E → K in Sol g 4.02. 1
Natural varianti123L → R in Sol g 4.02. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230383 mRNA Translation: AAF65312.1
AF230384 mRNA Translation: AAF65313.1

Similar proteinsi

Entry informationi

Entry nameiVA4_SOLGE
AccessioniPrimary (citable) accession number: Q9NH75
Secondary accession number(s): Q9NH74
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

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