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Protein

Venom allergen 4

Gene
N/A
Organism
Solenopsis geminata (Tropical fire ant)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Venom allergen 4
Alternative name(s):
Venom allergen IV
Allergen: Sol g 4
OrganismiSolenopsis geminata (Tropical fire ant)
Taxonomic identifieri121131 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaHymenopteraApocritaAculeataVespoideaFormicidaeMyrmicinaeSolenopsis

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. The most common cause of insect venom allergy in the southeastern United States is the imported fire ant.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei3479. Sol g 4.0101.
3480. Sol g 4.0201.
629. Sol g 4.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19By similarityAdd BLAST19
ChainiPRO_000002264720 – 137Venom allergen 4Add BLAST118

Proteomic databases

PRIDEiQ9NH75.

Expressioni

Tissue specificityi

Expressed by the venom gland.

Interactioni

Subunit structurei

Monomer.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the ant venom allergen 2/4 family.Curated

Keywords - Domaini

Signal

Family and domain databases

CDDicd12800. Sol_i_2. 1 hit.
Gene3Di1.10.238.20. 1 hit.
InterProiIPR020181. Ant_venom_allergen_Sol_i_2/4.
IPR006170. PBP_GOBP.
[Graphical view]
ProDomiPD031252. Ant_venom_allergen_Sol_i_2/4. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47565. SSF47565. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9NH75-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFVLVSCL LVFTQIIYAV DIKELKIMNR ILEKCIRTVP KGENDPINPL
60 70 80 90 100
KNVNVLYCAF SKRGIFTPKG VNTKQYINYC EKTIINPADI KQCKKLISKC
110 120 130
IKKVYDRPGP IIERSKNLLS CVLKKGVLEL TVYGKKK
Length:137
Mass (Da):15,667
Last modified:October 1, 2000 - v1
Checksum:iF888BF6D11CCA082
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti28M → V in Sol g 4.02. 1
Natural varianti33E → K in Sol g 4.02. 1
Natural varianti123L → R in Sol g 4.02. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230383 mRNA. Translation: AAF65312.1.
AF230384 mRNA. Translation: AAF65313.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230383 mRNA. Translation: AAF65312.1.
AF230384 mRNA. Translation: AAF65313.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei3479. Sol g 4.0101.
3480. Sol g 4.0201.
629. Sol g 4.

Proteomic databases

PRIDEiQ9NH75.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd12800. Sol_i_2. 1 hit.
Gene3Di1.10.238.20. 1 hit.
InterProiIPR020181. Ant_venom_allergen_Sol_i_2/4.
IPR006170. PBP_GOBP.
[Graphical view]
ProDomiPD031252. Ant_venom_allergen_Sol_i_2/4. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF47565. SSF47565. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiVA4_SOLGE
AccessioniPrimary (citable) accession number: Q9NH75
Secondary accession number(s): Q9NH74
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.