Q9NGV4 (Q9NGV4_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
SP1070 EMBL AAF63500.1

Gene names

Name:	uif FlyBase FBgn0031879
Synonyms:	SP1070 FlyBase FBgn0031879
ORF Names:	CG9138 FlyBase FBgn0031879

Organism

Drosophila melanogaster (Fruit fly)

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1551 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	EGF-like domain RuleBase RU000458 SAAS SAAS018097 Repeat SAAS SAAS009030
PTM	Disulfide bond SAAS SAAS018097
Gene Ontology (GO)
Biological process	regulation of tube architecture, open tracheal system Inferred from mutant phenotype. Source: FlyBase
Cellular component	apical plasma membrane Inferred from direct assay. Source: FlyBase
Molecular function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9NGV4 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: A97EA229E9384F31	FASTA	1,551	167,817
	10 20 30 40 50 60 MRTDSPASKG REQCKPVVCG EGACQHGGLC VPMGHDIQCF CPAGFSGRRC EQDIDECASQ 70 80 90 100 110 120 PCYNGGQCKD LPQGYRCECP AGYSGINCQE EASDCGNDTC PARAMCKNEP GYKNVTCLCR 130 140 150 160 170 180 SGYTGDQCDV TIDPCTANGN PCGNGASCQA LEQGRYKCEC VPGWEGIHCE QNINDCSENP 190 200 210 220 230 240 CLLGANCTDL VNDFQCACPP GFTGKRCEQK IDLCLSEPCK HGTCVDRLFD HECVCHPGWT 250 260 270 280 290 300 GSACDINIDD CENRPCANEG TCVDLVDGYS CNCEPGYTGK NCQHTIDDCA SNPCQHGATC 310 320 330 340 350 360 VDQLDGFSCK CRPGYVGLSC EAEIDECLSD PCNPVGTERC LDLDNKFECV CRDGFKGPLC 370 380 390 400 410 420 ATDIDDCEAQ PCLNNGICRD RVGGFECGCE PGWSGMRCEQ QVTTCGAQAP CQNDASCIDL 430 440 450 460 470 480 FQDYFCVCPS GTDGKNCETA PERCIGDPCM HGGKCQDFGS GLNCSCPADY SGIGCQYEYD 490 500 510 520 530 540 ACEEHVCQNG ATCVDNGAGY SCQCPPGFTG RNCEQDIVDC KDNSCPPGAT CVDLTNGFYC 550 560 570 580 590 600 QCPFNMTGDD CRKAIQVDYD LYFSDPSRST AAQVVPFPTG EANSLTVAMW VQFAQKDDRG 610 620 630 640 650 660 IFFTLYGVQS ARMTQQRRML LQAHSSGVQV SLFEDQPDAF LSFGEYTSVN DGQWHHVAVV 670 680 690 700 710 720 WDGISGQLQL ITEGLIASKM EYGAGGSLPG YLWAVLGLPQ PYGLSNELAY SDSGFQGTIT 730 740 750 760 770 780 KAQVWARALD ITSEIQKQVR DCRSEPVLYP GLILNWAGYE VTSGGVERNV PSLCGQRKCP 790 800 810 820 830 840 VGYTGANCQQ LVVDKEPPVV EHCPGDLWVI AKNGSAVVSW DEPHFSDNIG VTKIYERNGH 850 860 870 880 890 900 RSGTTLLWGT YDITYIASDA AGNTASCSFK VSLLTDFCPA LADPVGGSQV CKDWGAGGQF 910 920 930 940 950 960 KVCEIACNAG LRFSEPVPEF YTCGAEGFWR PTREPSMPLV YPSCSPSKPA QRVFRIKMLF 970 980 990 1000 1010 1020 PSDVLCNKAG QAVLRQKVTN SVNGLNRDWN FCSYAIEGTR ECKDIQIDVK CDHYRGTQNN 1030 1040 1050 1060 1070 1080 RVRRQAKDGG VYVMEAELPV VNDPVVHTST GERSTVKQLL EKLILEDDQF AVQEILPNTV 1090 1100 1110 1120 1130 1140 PDPASLELGS EYACPVGQVV MIPDCVPCAI GTFYDSANKT CIACSRGTYQ SEAGQLQCSK 1150 1160 1170 1180 1190 1200 CPVIAGRPGV TAGPGARSAA DCKERCPAGK YFDAETGLCR SCGHGFYQPN EGSFSCELCG 1210 1220 1230 1240 1250 1260 LGQTTRSTEA TSRKECRDEC SSGQQLGADG RCEPCPRGTY RLQGVQPSCA ACPLGRTTPK 1270 1280 1290 1300 1310 1320 VGASSVEECT LPVCSAGTYL NATQNMCIEC RKGYYQSESQ QTSCLQCPPN HSTKITGATS 1330 1340 1350 1360 1370 1380 KSECTNPCEH IAEGKPHCDV NAYCIMVPET SDFKCECKPG FNGTGMACTD VCDGFCENSG 1390 1400 1410 1420 1430 1440 ACVKDLKGTP SCRCVGSFTG PHCAERSEFA YIAGGIAGAV IFIIIIVLLI WMICVRSTKR 1450 1460 1470 1480 1490 1500 RDPKKMLTPA IDQTGSQVNF YYGAHTPYAE SIAPSHHSTY AHYYDDEEDG WEMPNFYNET 1510 1520 1530 1540 1550 YMKDGLHGGK MSTLARSNAS LYGTKEDLYD RLKRHAYTGK KEKSDSDSEV Q

References

[1]	"A reverse genetic screen for genes involved in Drosophila development." Serano T.L., Pendleton J.D., Rubin G.M. Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Endoplasmic reticulum EMBL AAF63500.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF239608 mRNA. Translation: AAF63500.1.
3D structure databases
HSSP	HSSP built from PDB template 1EDM based on UniProtKB P00740.
ProteinModelPortal	Q9NGV4.
SMR	Q9NGV4. Positions 20-555, 1107-1142, 1264-1406.
ModBase	Search...
Proteomic databases
PRIDE	Q9NGV4.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0031879. uif.
Phylogenomic databases
eggNOG	inNOG06250.
GeneTree	EMGT00050000000205.
InParanoid	Q9NGV4.
Gene expression databases
ArrayExpress	Q9NGV4.
Bgee	Q9NGV4.
Family and domain databases
InterPro	IPR008985. ConA-like_lec_gl. IPR013320. ConA-like_subgrp. IPR006209. EGF. IPR006210. EGF-like. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_reg_CS. IPR000152. EGF-type_Asp/Asn_hydroxyl_site. IPR000742. EGF_3. IPR018097. EGF_Ca-bd_CS. IPR009030. Growth_fac_rcpt. IPR003410. Hyalin. IPR011641. Tyr-kin_ephrin_A/B_rcpt-like. [Graphical view]
Gene3D	G3DSA:2.60.120.200. ConA_like_subgrp. 1 hit.
Pfam	PF00008. EGF. 10 hits. PF07699. GCC2_GCC3. 4 hits. PF02494. HYR. 1 hit. [Graphical view]
SMART	SM00181. EGF. 10 hits. SM00179. EGF_CA. 7 hits. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF57184. Grow_fac_recept. 1 hit.
PROSITE	PS00010. ASX_HYDROXYL. 9 hits. PS00022. EGF_1. 15 hits. PS01186. EGF_2. 12 hits. PS50026. EGF_3. 16 hits. PS01187. EGF_CA. 5 hits. PS50825. HYR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NGV4_DROME

Accession

Primary (citable) accession number: Q9NGV4

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)