Q9NG24 (Q9NG24_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Chromatin accessibility complex (CHRAC) EMBL CAB88669.1

Gene names

Name:	Acf1 FlyBase FBgn0027620
ORF Names:	CG1966 FlyBase FBgn0027620

Organism

Drosophila melanogaster (Fruit fly) EMBL CAB88669.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	1476 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	Zinc-finger SAAS SAAS001965
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Biological process	dendrite morphogenesis Inferred from mutant phenotype. Source: FlyBase epidermis development Inferred from mutant phenotype. Source: FlyBase muscle organ development Inferred from mutant phenotype. Source: FlyBase negative regulation of transcription, DNA-dependent Inferred from mutant phenotype. Source: FlyBase nucleosome assembly Inferred from direct assay. Source: FlyBase nucleosome mobilization Inferred from direct assay Ref.1. Source: FlyBase nucleosome positioning Inferred from direct assay. Source: FlyBase regulation of ATPase activity Inferred from direct assay. Source: FlyBase
Cellular component	ACF complex Inferred from direct assay. Source: FlyBase chromatin accessibility complex Inferred from direct assay Ref.1. Source: FlyBase
Molecular function	DNA binding Inferred from direct assay. Source: FlyBase protein binding Inferred from physical interaction. Source: FlyBase zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9NG24 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: F9E6FD1F1EFD8235	FASTA	1,476	170,471
	10 20 30 40 50 60 MPICKREGFD LNQKEGKNET FHDNDQVFCC YITKRIFRDY EHYFRHVMVI NSTVWQCEAT 70 80 90 100 110 120 GKENLTYEEA VKSERAARKK MEQFKQSLRS PVLLVVEHAQ QSAVNTLNMI VAKFLRKRYF 130 140 150 160 170 180 IGEEVSVQAK KNATYTVLGV KLDKNMPEPL NGIYEDTDNL VYRLRPNKGD PSAELDLPFR 190 200 210 220 230 240 QLRRSRMEFN LENLSMFIKS NVSRVDGLLR PKPEAYKQYV TDPGVNFSTI FIGKMPRYSP 250 260 270 280 290 300 AKIKKPDGKK QSTLNKYIVA GEATAAKSKA KAKSDAKSLA EELERVKREK EAKLIELEKQ 310 320 330 340 350 360 KAEKKAQLIE RVENECNLLL QKTDDLERTD QKVLPRYRQI VTLLPEHLLG DAFMMREFMH 370 380 390 400 410 420 TYTGLLSGIE VFRQNLSFYE MTRALTAREI AGPLSDILLV LLGTVFDLQK EEEEECAVTY 430 440 450 460 470 480 LDRAAQTQEP YWSMAQAAKS HLYAKRHFSF KVNELPLDAL TLNEVLRLHL LGSGAFVNEK 490 500 510 520 530 540 AERWRVMYRN GYSSKEDPGL ELRLEHSHIL RILKNHSVYQ LKFKDIMLLI RCLMSQIMTY 550 560 570 580 590 600 SGTINLIEER MEQTAKARQD LRALVVGENK RLAAVEINRK KLTQMHHLEV NGVEPEKREA 610 620 630 640 650 660 LVEKLKKSIA ELHAQSDQQH RKHELQMLKL HSQLFNFLVY LGMDRCYRKY YVLESMPGIF 670 680 690 700 710 720 VEHSPDSLDT CLEQPITNKS QIEIRQQSAL PKNRKDLRVY LLKLYGDDEK KTKKKAKHSL 730 740 750 760 770 780 ENKENQEHRL NGSAEPMDVE SDSPEAPTHF ELLMCSGDKR SCIVHDSRNG QRQRWAYIYK 790 800 810 820 830 840 AEEIDELIKA LNPNGLREYE LLQELSVLRS LIEQHAKTCP VDLLSLENET MRKKFMAAME 850 860 870 880 890 900 SETNRKYGEA NFGLPNGTDL NEVMRLHLVD RIIQFENDIY TGDLGRLKVK DMEKWRSDLL 910 920 930 940 950 960 GGNYDAQCKL QWGPGGKLED EAGSDNESHE THEEDDGALL GKYARKPYRD PGMYLAASAD 970 980 990 1000 1010 1020 TKPLPDSDDE EDQHTNAVSI PIAVHNMASA LLQVEQAIGK RFLKEPYGMK KWDPKQEALK 1030 1040 1050 1060 1070 1080 LACDSRLHQW EVSLMESTSF AQVFLHLNIL HDCIQWRRST NKSLCKVCRR GSDPEKMLLC 1090 1100 1110 1120 1130 1140 DECNAGTHMF CLKPKLRSVP PGNWYCNDCV KSLGLSNGQN EKDKKQATKK KRKFIVEEED 1150 1160 1170 1180 1190 1200 DEATDEEEEE KKDDDMTDED AEHENEKHDE DVEDDESVTS TPSSSRVNGR ILRRPRTRPT 1210 1220 1230 1240 1250 1260 SRRLTSKEIE EHAQEDVDSG DVSDDASLTA GEDTIEDESD EEKVCQKCFY DGGEIKCVQC 1270 1280 1290 1300 1310 1320 RLFFHLECVH LKRPPRTDFV CKTCKPMPQR PRRRHSNMNG DHDRDEEEPK AKRPRNSLRL 1330 1340 1350 1360 1370 1380 CIDKTARPSN GNNNNNNNNS SVNNNNHRRS GRRTNEHMPL NSAALYDLLE QIMKHKAAWP 1390 1400 1410 1420 1430 1440 FLRPVLTSEV PDYHQIIKTP MDLAKIKSKL NMGAYQLNEE LLSDIQLVFR NCDLYNVEGN 1450 1460 1470 EIYDAGCQLE RFVIDRCRDM QLPFRPSDMN GEVKAC

References

[1]	"Acf1, the largest subunit of CHRAC, regulates ISWI-induced nucleosome remodelling." Eberharter A., Ferrari S., Langst G., Straub T., Imhof A., Varga-Weisz P., Wilm M., Becker P.B. EMBO J. 20:3781-3788(2001) [PubMed: 11447119] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ238397 mRNA. Translation: CAB88669.1.
3D structure databases
HSSP	HSSP built from PDB template 1F62 based on UniProtKB Q9UIG0.
ProteinModelPortal	Q9NG24.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NG24.
Proteomic databases
PRIDE	Q9NG24.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0027620. Acf1.
Phylogenomic databases
InParanoid	Q9NG24.
Gene expression databases
ArrayExpress	Q9NG24.
Bgee	Q9NG24.
Family and domain databases
InterPro	IPR001487. Bromodomain. IPR018500. DDT_dom_subgr. IPR018501. DDT_dom_superfamily. IPR013136. WSTF_Acf1_Cbp146. IPR019786. Zinc_finger_PHD-type_CS. IPR011011. Znf_FYVE_PHD. IPR001965. Znf_PHD. IPR019787. Znf_PHD-finger. IPR013083. Znf_RING/FYVE/PHD. [Graphical view]
Gene3D	G3DSA:1.20.920.10. Bromodomain. 1 hit. G3DSA:3.30.40.10. Znf_RING/FYVE/PHD. 2 hits.
Pfam	PF00439. Bromodomain. 1 hit. PF00628. PHD. 1 hit. PF10537. WAC_Acf1_DNA_bd. 1 hit. [Graphical view]
PRINTS	PR00503. BROMODOMAIN.
SMART	SM00297. BROMO. 1 hit. SM00571. DDT. 1 hit. SM00249. PHD. 2 hits. [Graphical view]
SUPFAM	SSF47370. Bromodomain. 1 hit. SSF57903. FYVE_PHD_ZnF. 2 hits.
PROSITE	PS50014. BROMODOMAIN_2. 1 hit. PS50827. DDT. 1 hit. PS51136. WAC. 1 hit. PS01359. ZF_PHD_1. 2 hits. PS50016. ZF_PHD_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NG24_DROME

Accession

Primary (citable) accession number: Q9NG24

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	January 25, 2012
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)