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Q9NFQ4 (ALL22_GLYDO) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Mite group 2 allergen Gly d 2.02
Alternative name(s):
Allergen=Gly d 2.02
OrganismGlycyphagus domesticus (House itch mite)
Taxonomic identifier105145 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataGlycyphagoideaGlycyphagidaeGlycyphagus

Protein attributes

Sequence length125 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Secreted.

Allergenic properties

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Sequence similarities

Belongs to the NPC2 family.

Ontologies

Keywords
   Cellular componentSecreted
   DiseaseAllergen
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 125125Mite group 2 allergen Gly d 2.02
PRO_0000221049

Sequences

Sequence LengthMass (Da)Tools
Q9NFQ4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 63607D3C6BF0AAE0

FASTA12513,366
        10         20         30         40         50         60 
GKMKFKDCGK GEVTELDITD CSGDFCVIHR GKPLTLEAKF AANQDTTKAT IKVLAKVAGT 

        70         80         90        100        110        120 
PIQVPGLETD GCKFVKCPIK KGDPIDFKYT TTVPAILPKV KAEVTAELVG DHGVLACGRF 


GRQVE 

« Hide

References

[1]"Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens."
Gafvelin G., Johansson E., Lundin A., Smith A.M., Chapman M.D., Benjamin D.C., Derewenda U., van Hage-Hamsten M.
J. Allergy Clin. Immunol. 107:511-518(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 1-18.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ272216 mRNA. Translation: CAB76459.1.

3D structure databases

ProteinModelPortalQ9NFQ4.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome365. Gly d 2.
367. Gly d 2.0201.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.40.770. 1 hit.
InterProIPR014756. Ig_E-set.
IPR003172. ML_dom.
[Graphical view]
PfamPF02221. E1_DerP2_DerF2. 1 hit.
[Graphical view]
SMARTSM00737. ML. 1 hit.
[Graphical view]
SUPFAMSSF81296. SSF81296. 1 hit.
ProtoNetSearch...

Entry information

Entry nameALL22_GLYDO
AccessionPrimary (citable) accession number: Q9NFQ4
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2000
Last modified: October 16, 2013
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries