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Protein

Mite group 2 allergen Gly d 2.02

Gene
N/A
Organism
Glycyphagus domesticus (House itch mite)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Mite group 2 allergen Gly d 2.02
Alternative name(s):
Allergen: Gly d 2.02
OrganismiGlycyphagus domesticus (House itch mite)
Taxonomic identifieri105145 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaChelicerataArachnidaAcariAcariformesSarcoptiformesAstigmataGlycyphagoideaGlycyphagidaeGlycyphagus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Secreted

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei365. Gly d 2.
367. Gly d 2.0201.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 125125Mite group 2 allergen Gly d 2.02PRO_0000221049Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9NFQ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NPC2 family.Curated

Family and domain databases

Gene3Di2.60.40.770. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR003172. ML_dom.
[Graphical view]
PfamiPF02221. E1_DerP2_DerF2. 1 hit.
[Graphical view]
SMARTiSM00737. ML. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NFQ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GKMKFKDCGK GEVTELDITD CSGDFCVIHR GKPLTLEAKF AANQDTTKAT
60 70 80 90 100
IKVLAKVAGT PIQVPGLETD GCKFVKCPIK KGDPIDFKYT TTVPAILPKV
110 120
KAEVTAELVG DHGVLACGRF GRQVE
Length:125
Mass (Da):13,366
Last modified:October 1, 2000 - v1
Checksum:i63607D3C6BF0AAE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272216 mRNA. Translation: CAB76459.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ272216 mRNA. Translation: CAB76459.1.

3D structure databases

ProteinModelPortaliQ9NFQ4.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei365. Gly d 2.
367. Gly d 2.0201.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.770. 1 hit.
InterProiIPR014756. Ig_E-set.
IPR003172. ML_dom.
[Graphical view]
PfamiPF02221. E1_DerP2_DerF2. 1 hit.
[Graphical view]
SMARTiSM00737. ML. 1 hit.
[Graphical view]
SUPFAMiSSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Cross-reactivity studies of a new group 2 allergen from the dust mite Glycyphagus domesticus, Gly d 2, and group 2 allergens from Dermatophagoides pteronyssinus, Lepidoglyphus destructor, and Tyrophagus putrescentiae with recombinant allergens."
    Gafvelin G., Johansson E., Lundin A., Smith A.M., Chapman M.D., Benjamin D.C., Derewenda U., van Hage-Hamsten M.
    J. Allergy Clin. Immunol. 107:511-518(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 1-18.

Entry informationi

Entry nameiALL22_GLYDO
AccessioniPrimary (citable) accession number: Q9NFQ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: October 1, 2000
Last modified: January 7, 2015
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.