SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9NES8

- Q9NES8_CAEEL

UniProt

Q9NES8 - Q9NES8_CAEEL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name: Protein PPH-5, isoform a
Gene
pph-5, CELE_Y39B6A.2, Y39B6A.2
Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi241 – 2411Iron By similarityUniRule annotation
Metal bindingi243 – 2431Iron By similarityUniRule annotation
Metal bindingi270 – 2701Iron By similarityUniRule annotation
Active sitei303 – 3031Proton donor By similarityUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. negative regulation of exocytosis Source: WormBase
  2. protein dephosphorylation Source: InterPro
  3. protein localization to organelle Source: WormBase
Complete GO annotation...

Keywords - Ligandi

IronUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein PPH-5, isoform aImported
Gene namesi
Name:pph-5Imported
ORF Names:CELE_Y39B6A.2Imported, Y39B6A.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiY39B6A.2a; CE36619; WBGene00012665; pph-5.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: WormBase
  2. mitotic spindle Source: WormBase
  3. nucleus Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9NES8.

Interactioni

Protein-protein interaction databases

DIPiDIP-25900N.
IntActiQ9NES8. 3 interactions.
MINTiMINT-1080507.
STRINGi6239.Y39B6A.2.

Structurei

3D structure databases

ProteinModelPortaliQ9NES8.
SMRiQ9NES8. Positions 27-493.

Family & Domainsi

Keywords - Domaini

TPR repeatSAAS annotations

Phylogenomic databases

eggNOGiCOG0639.
GeneTreeiENSGT00530000063173.
HOGENOMiHOG000172698.
InParanoidiQ9NES8.
KOiK04460.
OMAiFKLLYPN.
PhylomeDBiQ9NES8.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11668:SF12. PTHR11668:SF12. 1 hit.
PfamiPF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF00515. TPR_1. 1 hit.
[Graphical view]
PIRSFiPIRSF033096. PPPtase_5. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NES8-1 [UniParc]FASTAAdd to Basket

« Hide

MAATITDDIV ATVLESIEEK SYEDEKEKAG MIKDEANQFF KDQVYDVAAD    50
LYSVAIEIHP TAVLYGNRAQ AYLKKELYGS ALEDADNAIA IDPSYVKGFY 100
RRATANMALG RFKKALTDYQ AVVKVCPNDK DARAKFDECS KIVRRQKFEA 150
AISTDHDKKT VAETLDINAM AIEDSYDGPR LEDKITKEFV LQLIKTFKNQ 200
QKLHKKYAFK MLLEFYNYVK SLPTMVEITV PTGKKFTICG DVHGQFYDLC 250
NIFEINGYPS ETNPYLFNGD FVDRGSFSVE TIFTMIGFKL LYPNHFFMSR 300
GNHESDVMNK MYGFEGEVKA KYTQQMCDMF TETFCWLPLC HLINEKIFVC 350
HGGLFKEDGV TLEDIRKTDR NRQPPDEGIM CDLLWSDPQP INGRSPSKRG 400
VGCQFGPDVT SKWCETNGIE YVVRSHEVKP EGYEMHHNGQ CFTVFSAPNY 450
CDQMNNKGAF ITITGDNLTP RFTPFDAVPH PKLPPMAYAN SLFGFN 496
Length:496
Mass (Da):56,462
Last modified:September 13, 2004 - v2
Checksum:i2C872FF1700384EE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL132948 Genomic DNA. Translation: CAC51076.2.
PIRiT45058.
RefSeqiNP_001256849.1. NM_001269920.1.
UniGeneiCel.1820.

Genome annotation databases

EnsemblMetazoaiY39B6A.2a; Y39B6A.2a; WBGene00012665.
GeneIDi180263.
KEGGicel:CELE_Y39B6A.2.
UCSCiY39B6A.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL132948 Genomic DNA. Translation: CAC51076.2 .
PIRi T45058.
RefSeqi NP_001256849.1. NM_001269920.1.
UniGenei Cel.1820.

3D structure databases

ProteinModelPortali Q9NES8.
SMRi Q9NES8. Positions 27-493.
ModBasei Search...

Protein-protein interaction databases

DIPi DIP-25900N.
IntActi Q9NES8. 3 interactions.
MINTi MINT-1080507.
STRINGi 6239.Y39B6A.2.

Proteomic databases

PaxDbi Q9NES8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y39B6A.2a ; Y39B6A.2a ; WBGene00012665 .
GeneIDi 180263.
KEGGi cel:CELE_Y39B6A.2.
UCSCi Y39B6A.2. c. elegans.

Organism-specific databases

CTDi 180263.
WormBasei Y39B6A.2a ; CE36619 ; WBGene00012665 ; pph-5.

Phylogenomic databases

eggNOGi COG0639.
GeneTreei ENSGT00530000063173.
HOGENOMi HOG000172698.
InParanoidi Q9NES8.
KOi K04460.
OMAi FKLLYPN.
PhylomeDBi Q9NES8.

Miscellaneous databases

NextBioi 908634.
PROi Q9NES8.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR11668:SF12. PTHR11668:SF12. 1 hit.
Pfami PF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF00515. TPR_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF033096. PPPtase_5. 1 hit.
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiQ9NES8_CAEEL
AccessioniPrimary (citable) accession number: Q9NES8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: September 13, 2004
Last modified: July 9, 2014
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi