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Q9NES8

- Q9NES8_CAEEL

UniProt

Q9NES8 - Q9NES8_CAEEL

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Protein
Submitted name:

Protein PPH-5, isoform a

Gene

pph-5

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi241 – 2411IronUniRule annotation
Metal bindingi243 – 2431IronUniRule annotation
Metal bindingi270 – 2701IronUniRule annotation
Active sitei303 – 3031Proton donorUniRule annotation

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: InterPro

GO - Biological processi

  1. negative regulation of exocytosis Source: WormBase
  2. protein dephosphorylation Source: InterPro
  3. protein localization to organelle Source: WormBase
Complete GO annotation...

Keywords - Ligandi

IronUniRule annotation, Metal-bindingUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein PPH-5, isoform aImported
Gene namesi
Name:pph-5Imported
ORF Names:CELE_Y39B6A.2Imported, Y39B6A.2Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome V

Organism-specific databases

WormBaseiY39B6A.2a; CE36619; WBGene00012665; pph-5.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: WormBase
  2. mitotic spindle Source: WormBase
  3. nucleus Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ9NES8.

Expressioni

Gene expression databases

ExpressionAtlasiQ9NES8. baseline.

Interactioni

Protein-protein interaction databases

DIPiDIP-25900N.
IntActiQ9NES8. 3 interactions.
MINTiMINT-1080507.
STRINGi6239.Y39B6A.2.

Structurei

3D structure databases

ProteinModelPortaliQ9NES8.
SMRiQ9NES8. Positions 27-493.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0639.
GeneTreeiENSGT00530000063173.
HOGENOMiHOG000172698.
InParanoidiQ9NES8.
KOiK04460.
OMAiFKLLYPN.
PhylomeDBiQ9NES8.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PANTHERiPTHR11668:SF12. PTHR11668:SF12. 1 hit.
PfamiPF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF00515. TPR_1. 1 hit.
[Graphical view]
PIRSFiPIRSF033096. PPPtase_5. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NES8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAATITDDIV ATVLESIEEK SYEDEKEKAG MIKDEANQFF KDQVYDVAAD
60 70 80 90 100
LYSVAIEIHP TAVLYGNRAQ AYLKKELYGS ALEDADNAIA IDPSYVKGFY
110 120 130 140 150
RRATANMALG RFKKALTDYQ AVVKVCPNDK DARAKFDECS KIVRRQKFEA
160 170 180 190 200
AISTDHDKKT VAETLDINAM AIEDSYDGPR LEDKITKEFV LQLIKTFKNQ
210 220 230 240 250
QKLHKKYAFK MLLEFYNYVK SLPTMVEITV PTGKKFTICG DVHGQFYDLC
260 270 280 290 300
NIFEINGYPS ETNPYLFNGD FVDRGSFSVE TIFTMIGFKL LYPNHFFMSR
310 320 330 340 350
GNHESDVMNK MYGFEGEVKA KYTQQMCDMF TETFCWLPLC HLINEKIFVC
360 370 380 390 400
HGGLFKEDGV TLEDIRKTDR NRQPPDEGIM CDLLWSDPQP INGRSPSKRG
410 420 430 440 450
VGCQFGPDVT SKWCETNGIE YVVRSHEVKP EGYEMHHNGQ CFTVFSAPNY
460 470 480 490
CDQMNNKGAF ITITGDNLTP RFTPFDAVPH PKLPPMAYAN SLFGFN
Length:496
Mass (Da):56,462
Last modified:September 13, 2004 - v2
Checksum:i2C872FF1700384EE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132948 Genomic DNA. Translation: CAC51076.2.
PIRiT45058.
RefSeqiNP_001256849.1. NM_001269920.1.
UniGeneiCel.1820.

Genome annotation databases

EnsemblMetazoaiY39B6A.2a; Y39B6A.2a; WBGene00012665.
GeneIDi180263.
KEGGicel:CELE_Y39B6A.2.
UCSCiY39B6A.2. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132948 Genomic DNA. Translation: CAC51076.2 .
PIRi T45058.
RefSeqi NP_001256849.1. NM_001269920.1.
UniGenei Cel.1820.

3D structure databases

ProteinModelPortali Q9NES8.
SMRi Q9NES8. Positions 27-493.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-25900N.
IntActi Q9NES8. 3 interactions.
MINTi MINT-1080507.
STRINGi 6239.Y39B6A.2.

Proteomic databases

PaxDbi Q9NES8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai Y39B6A.2a ; Y39B6A.2a ; WBGene00012665 .
GeneIDi 180263.
KEGGi cel:CELE_Y39B6A.2.
UCSCi Y39B6A.2. c. elegans.

Organism-specific databases

CTDi 180263.
WormBasei Y39B6A.2a ; CE36619 ; WBGene00012665 ; pph-5.

Phylogenomic databases

eggNOGi COG0639.
GeneTreei ENSGT00530000063173.
HOGENOMi HOG000172698.
InParanoidi Q9NES8.
KOi K04460.
OMAi FKLLYPN.
PhylomeDBi Q9NES8.

Miscellaneous databases

NextBioi 908634.
PROi Q9NES8.

Gene expression databases

ExpressionAtlasi Q9NES8. baseline.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR006186. Ser/Thr-sp_prot-phosphatase.
IPR011236. Ser/Thr_PPase_5.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view ]
PANTHERi PTHR11668:SF12. PTHR11668:SF12. 1 hit.
Pfami PF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
PF00515. TPR_1. 1 hit.
[Graphical view ]
PIRSFi PIRSF033096. PPPtase_5. 1 hit.
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS50005. TPR. 2 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2Imported.

Entry informationi

Entry nameiQ9NES8_CAEEL
AccessioniPrimary (citable) accession number: Q9NES8
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: September 13, 2004
Last modified: October 29, 2014
This is version 107 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3