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Q9NES8

- Q9NES8_CAEEL

UniProt

Q9NES8 - Q9NES8_CAEEL

Protein
Submitted name:

Protein PPH-5, isoform a

Gene

pph-5

Organism
Caenorhabditis elegans
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 106 (01 Oct 2014)
      Sequence version 2 (13 Sep 2004)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi241 – 2411IronUniRule annotation
    Metal bindingi243 – 2431IronUniRule annotation
    Metal bindingi270 – 2701IronUniRule annotation
    Active sitei303 – 3031Proton donorUniRule annotation

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: InterPro

    GO - Biological processi

    1. negative regulation of exocytosis Source: WormBase
    2. protein dephosphorylation Source: InterPro
    3. protein localization to organelle Source: WormBase

    Keywords - Ligandi

    IronUniRule annotation, Metal-bindingUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Protein PPH-5, isoform aImported
    Gene namesi
    Name:pph-5Imported
    ORF Names:CELE_Y39B6A.2Imported, Y39B6A.2Imported
    OrganismiCaenorhabditis elegansImported
    Taxonomic identifieri6239 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
    ProteomesiUP000001940: Chromosome V

    Organism-specific databases

    WormBaseiY39B6A.2a; CE36619; WBGene00012665; pph-5.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: WormBase
    2. mitotic spindle Source: WormBase
    3. nucleus Source: InterPro

    PTM / Processingi

    Proteomic databases

    PaxDbiQ9NES8.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-25900N.
    IntActiQ9NES8. 3 interactions.
    MINTiMINT-1080507.
    STRINGi6239.Y39B6A.2.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9NES8.
    SMRiQ9NES8. Positions 27-493.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    TPR repeatSAAS annotation

    Phylogenomic databases

    eggNOGiCOG0639.
    GeneTreeiENSGT00530000063173.
    HOGENOMiHOG000172698.
    InParanoidiQ9NES8.
    KOiK04460.
    OMAiFKLLYPN.
    PhylomeDBiQ9NES8.

    Family and domain databases

    Gene3Di1.25.40.10. 1 hit.
    3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR013235. PPP_dom.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    IPR011236. Ser/Thr_PPase_5.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR001440. TPR_1.
    IPR019734. TPR_repeat.
    [Graphical view]
    PANTHERiPTHR11668:SF12. PTHR11668:SF12. 1 hit.
    PfamiPF00149. Metallophos. 1 hit.
    PF08321. PPP5. 1 hit.
    PF00515. TPR_1. 1 hit.
    [Graphical view]
    PIRSFiPIRSF033096. PPPtase_5. 1 hit.
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS50005. TPR. 2 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9NES8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAATITDDIV ATVLESIEEK SYEDEKEKAG MIKDEANQFF KDQVYDVAAD    50
    LYSVAIEIHP TAVLYGNRAQ AYLKKELYGS ALEDADNAIA IDPSYVKGFY 100
    RRATANMALG RFKKALTDYQ AVVKVCPNDK DARAKFDECS KIVRRQKFEA 150
    AISTDHDKKT VAETLDINAM AIEDSYDGPR LEDKITKEFV LQLIKTFKNQ 200
    QKLHKKYAFK MLLEFYNYVK SLPTMVEITV PTGKKFTICG DVHGQFYDLC 250
    NIFEINGYPS ETNPYLFNGD FVDRGSFSVE TIFTMIGFKL LYPNHFFMSR 300
    GNHESDVMNK MYGFEGEVKA KYTQQMCDMF TETFCWLPLC HLINEKIFVC 350
    HGGLFKEDGV TLEDIRKTDR NRQPPDEGIM CDLLWSDPQP INGRSPSKRG 400
    VGCQFGPDVT SKWCETNGIE YVVRSHEVKP EGYEMHHNGQ CFTVFSAPNY 450
    CDQMNNKGAF ITITGDNLTP RFTPFDAVPH PKLPPMAYAN SLFGFN 496
    Length:496
    Mass (Da):56,462
    Last modified:September 13, 2004 - v2
    Checksum:i2C872FF1700384EE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL132948 Genomic DNA. Translation: CAC51076.2.
    PIRiT45058.
    RefSeqiNP_001256849.1. NM_001269920.1.
    UniGeneiCel.1820.

    Genome annotation databases

    EnsemblMetazoaiY39B6A.2a; Y39B6A.2a; WBGene00012665.
    GeneIDi180263.
    KEGGicel:CELE_Y39B6A.2.
    UCSCiY39B6A.2. c. elegans.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL132948 Genomic DNA. Translation: CAC51076.2 .
    PIRi T45058.
    RefSeqi NP_001256849.1. NM_001269920.1.
    UniGenei Cel.1820.

    3D structure databases

    ProteinModelPortali Q9NES8.
    SMRi Q9NES8. Positions 27-493.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-25900N.
    IntActi Q9NES8. 3 interactions.
    MINTi MINT-1080507.
    STRINGi 6239.Y39B6A.2.

    Proteomic databases

    PaxDbi Q9NES8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblMetazoai Y39B6A.2a ; Y39B6A.2a ; WBGene00012665 .
    GeneIDi 180263.
    KEGGi cel:CELE_Y39B6A.2.
    UCSCi Y39B6A.2. c. elegans.

    Organism-specific databases

    CTDi 180263.
    WormBasei Y39B6A.2a ; CE36619 ; WBGene00012665 ; pph-5.

    Phylogenomic databases

    eggNOGi COG0639.
    GeneTreei ENSGT00530000063173.
    HOGENOMi HOG000172698.
    InParanoidi Q9NES8.
    KOi K04460.
    OMAi FKLLYPN.
    PhylomeDBi Q9NES8.

    Miscellaneous databases

    NextBioi 908634.
    PROi Q9NES8.

    Family and domain databases

    Gene3Di 1.25.40.10. 1 hit.
    3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR013235. PPP_dom.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    IPR011236. Ser/Thr_PPase_5.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR001440. TPR_1.
    IPR019734. TPR_repeat.
    [Graphical view ]
    PANTHERi PTHR11668:SF12. PTHR11668:SF12. 1 hit.
    Pfami PF00149. Metallophos. 1 hit.
    PF08321. PPP5. 1 hit.
    PF00515. TPR_1. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF033096. PPPtase_5. 1 hit.
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS50005. TPR. 2 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
      The C. elegans sequencing consortium
      Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Bristol N2Imported.

    Entry informationi

    Entry nameiQ9NES8_CAEEL
    AccessioniPrimary (citable) accession number: Q9NES8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: October 1, 2000
    Last sequence update: September 13, 2004
    Last modified: October 1, 2014
    This is version 106 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3