Q9NBK6 (Q9NBK6_DROME) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Toll-3 EMBL AAF86229.1

Gene names

Name:	MstProx FlyBase FBgn0015770
ORF Names:	CG1149 FlyBase FBgn0015770

Organism

Drosophila melanogaster (Fruit fly) EMBL AAF86229.1

Taxonomic identifier

7227 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length	785 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 TIR domain. SAAS SAAS000157

Ontologies

Keywords
Cellular component	Membrane
Domain	Repeat SAAS SAAS000157 Transmembrane Transmembrane helix SAAS SAAS000157
Gene Ontology (GO)
Biological process	innate immune response Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	transmembrane signaling receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL AAF86229.1

Sequences

	Sequence		Length	Mass (Da)
	Q9NBK6 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: C8EFA786D7CA9525	FASTA	785	91,898
	10 20 30 40 50 60 SHLRSLTFIG FQIENLSTKP FAQFINLKRM VLTNCTVRNL TFLRTLQKSL EHLELDIDNE 70 80 90 100 110 120 VDLKYFTNFS SLKFMKVRNY IPNKNFTALI CTHKNCNFIR GINGLECPKL CQCLYIIDDL 130 140 150 160 170 180 ELNIDCSNLG LLQIPPLPIP IYGDVKLNFS NNSLSQLPTM TLPGYKLVKR LDVSRNRLTN 190 200 210 220 230 240 LSINHLPAKL DYLDVSFNEI INMGNDVIKY LRTVPIFKQT GNQWTIHCDD KPLLNFFRHL 250 260 270 280 290 300 KLIIRMKSAE MKPMFLHSLT ELPKGFLKFL GKHFIWLGVR KQEYYLINEE QLLQSMHRKL 310 320 330 340 350 360 NNLNTIMSIY KYMEWLHRKL IFVNREYDLF YIRQMAAPCP HKCECCYSRD SLILKIDCRN 370 380 390 400 410 420 KFVYNFPDIV ARNSRLMRKQ NMSSPMELHL SKNNISNITI AMLPKELRFL DLRFNNLVTL 430 440 450 460 470 480 DDKVLSYLKK NSIKTKLSGN PWNCDCKSRS VLSILRDHEP LEYDVTLKRC NISPTDCPDV 490 500 510 520 530 540 CVCCLDNLTW PSFIVDCRGE GLLQMPSLSS RVTYVDLRNN NLTALSQKNR SSIENRSLKL 550 560 570 580 590 600 HLLDNPWSCS CNDIEKINFM KSVSSSIVDF TEIKCSNGEK LVSINQHIVC PSDLFYYLAL 610 620 630 640 650 660 AISLVATIIA LNFLIWFRQP VLVWFYEHGV CLSLAAKREL DKDKRFDAFL AFTHKDEALL 670 680 690 700 710 720 EEFVDRLERG RPRFQLCFYL RDWLAGESIP DCIGQSIKDS RRIIVLMTEN FMNSTWGRLE 730 740 750 760 770 780 FRLALHATSR DRCKRLIVVL YPNVKNFDSL DSELRTYMAF NTYLERSHPN FWNKLIYSMP HTKLR

References

[1]	"Toll-related receptors and the control of antimicrobial peptide expression in Drosophila." Tauszig S., Jouanguy E., Hoffmann J.A., Imler J.L. Proc. Natl. Acad. Sci. U.S.A. 97:10520-10525(2000) [PubMed: 10973475] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF247769 mRNA. Translation: AAF86229.1.
3D structure databases
HSSP	HSSP built from PDB template 1O77 based on UniProtKB O60603.
ProteinModelPortal	Q9NBK6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q9NBK6.
Proteomic databases
PRIDE	Q9NBK6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
FlyBase	FBgn0015770. MstProx.
Phylogenomic databases
InParanoid	Q9NBK6.
Gene expression databases
ArrayExpress	Q9NBK6.
Bgee	Q9NBK6.
Family and domain databases
InterPro	IPR004075. IL1_rcpt_1. IPR000372. LRR-contain_N. IPR000157. TIR_dom. [Graphical view]
Pfam	PF01582. TIR. 1 hit. [Graphical view]
PRINTS	PR01537. INTRLKN1R1F.
SMART	SM00013. LRRNT. 3 hits. SM00255. TIR. 1 hit. [Graphical view]
SUPFAM	SSF52200. TIR. 1 hit.
PROSITE	PS50104. TIR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q9NBK6_DROME

Accession

Primary (citable) accession number: Q9NBK6

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2000
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)