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Q9NB97

- Q9NB97_DROME

UniProt

Q9NB97 - Q9NB97_DROME

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Protein

Transporter

Gene
DAT, CG8380
Organism
Drosophila melanogaster (Fruit fly)
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. cocaine binding Source: FlyBase
  2. dopamine transmembrane transporter activity Source: FlyBase
  3. neurotransmitter:sodium symporter activity Source: InterPro

GO - Biological processi

  1. circadian sleep/wake cycle Source: FlyBase
  2. dopamine transport Source: FlyBase
  3. sleep Source: FlyBase
Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotationSAAS annotations, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
Gene namesi
Name:DATImported
ORF Names:CG8380Imported
OrganismiDrosophila melanogaster (Fruit fly)Imported
Taxonomic identifieri7227 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora

Organism-specific databases

FlyBaseiFBgn0034136. DAT.

Subcellular locationi

GO - Cellular componenti

  1. integral component of plasma membrane Source: FlyBase
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ9NB97.

Expressioni

Gene expression databases

BgeeiQ9NB97.

Structurei

3D structure databases

ProteinModelPortaliQ9NB97.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

InParanoidiQ9NB97.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR00176. NANEUSMPORT.
PROSITEiPS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9NB97-1 [UniParc]FASTAAdd to Basket

« Hide

MSPTGHISKS KTPTPRDNDN NSISDERETW SGKVDFLLSV IGFAVDLANV    50
WRFPYLCYKN GGGAFLVPYG IMLVVGGIPL FYMELALGQH NRKGAITCWG 100
RLVPLFKGIG YAVVLIAFYV DFYYNVIIAW SLRFFFASFT NSLPWTSCNN 150
IWNTPNCRPF ESQNASRVPV IGNYSDLYAM GNQSLLYNET YMNGSSLDTS 200
AVGHVEGFQS AASEYFNRYI LELNRSEGIH DLGAIKWDMA LCLLIVYLIC 250
YFSLWKGIST SGKVVWFTAL FPYAVLLILL IRGLTLPGSF LGIQYYLTPN 300
FSAIYKAEVW VDAATQVFFS LGPGFGVLLA YASYNKYHNN VYKDALLTSF 350
INSATSFIAG FVIFSVLGYM AHTLGVRIED VATEGPGLVF VVYPAAIATM 400
PASTFWALIF FMMLLTLGLD SSFGGSEAII TALSDEFPKI KRNRELFVAG 450
LFSLYFVVGL ASCTQGGFYF FHLLDRYAAG YSILVAVFFE AIAVSWIYGT 500
NRFSEDIRDM IGFPPGRYWQ VCWRFVAPIF LLFITVYGLI GYEPLTYADY 550
VYPSWANALG WCIAGSSVVM IPAVAIFKLL STPGSLRQRF TILTTPWRDQ 600
QSMAMVLNGV TTEVTVVRLT DTETAKEPVD V 631
Length:631
Mass (Da):70,349
Last modified:October 1, 2000 - v1
Checksum:iABF3B53F5A91ED89
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF260833 mRNA. Translation: AAF76882.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF260833 mRNA. Translation: AAF76882.1 .

3D structure databases

ProteinModelPortali Q9NB97.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9NB97.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

FlyBasei FBgn0034136. DAT.

Phylogenomic databases

InParanoidi Q9NB97.

Gene expression databases

Bgeei Q9NB97.

Family and domain databases

InterProi IPR000175. Na/ntran_symport.
[Graphical view ]
PANTHERi PTHR11616. PTHR11616. 1 hit.
Pfami PF00209. SNF. 1 hit.
[Graphical view ]
PRINTSi PR00176. NANEUSMPORT.
PROSITEi PS00610. NA_NEUROTRAN_SYMP_1. 1 hit.
PS00754. NA_NEUROTRAN_SYMP_2. 1 hit.
PS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of neurotransmitter transporters from Drosophila melanogaster."
    Porzgen P., Sonders M.S., Reed A.I., Ingram S.L., Amara S.G.
    Abstr. - Soc. Neurosci. 25:160-160(1999)
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HeadImported.
  2. "The antidepressant-sensitive dopamine transporter in Drosophila melanogaster: a primordial carrier for catecholamines."
    Porzgen P., Park S.K., Hirsh J., Sonders M.S., Amara S.G.
    Mol. Pharmacol. 59:83-95(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HeadImported.

Entry informationi

Entry nameiQ9NB97_DROME
AccessioniPrimary (citable) accession number: Q9NB97
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: April 16, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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