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Protein

Alcohol dehydrogenase

Gene

ADH

Organism
Bactrocera oleae (Olive fruit fly) (Dacus oleae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

An alcohol + NAD+ = an aldehyde or ketone + NADH.PROSITE-ProRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei137SubstrateBy similarity1
Active sitei150Proton acceptorPROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi9 – 33NADBy similarityAdd BLAST25

GO - Molecular functioni

  • alcohol dehydrogenase (NAD) activity Source: UniProtKB

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Alcohol dehydrogenase (EC:1.1.1.1)
Gene namesi
Name:ADH
OrganismiBactrocera oleae (Olive fruit fly) (Dacus oleae)
Taxonomic identifieri104688 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaTephritoideaTephritidaeBactroceraDaculus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000544501 – 258Alcohol dehydrogenaseAdd BLAST258

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9NAR7.
SMRiQ9NAR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

InterProiView protein in InterPro
IPR002426. ADH_Ceratitis-type.
IPR002424. ADH_insect.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
PfamiView protein in Pfam
PF00106. adh_short. 1 hit.
PRINTSiPR01169. CERATITISADH.
PR01167. INSADHFAMILY.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiView protein in PROSITE
PS00061. ADH_SHORT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9NAR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSGKNVVF VGGLGFIGYE ACKQIMTKNV ASFFVFDVLE NAENIKALQA
60 70 80 90 100
INPKTKVYYT KFDITNKASI KSAFADVIAK VQYIDVLVNG AGILTDPNVE
110 120 130 140 150
LTMNINLIGL INTTLEAIPL MDKNKKGRGG LIVNIASVLG LEPAPPAAIY
160 170 180 190 200
CASKFGVMGF SRSISDPYYY NLTGIAVATF CPGLTETPLK NNIATKYTFE
210 220 230 240 250
YSKVIGDKLN NTKTQKPEAC GAHLAQVLDT AENGGIYISN QGTLSKVTPT

VYWQPTFN
Length:258
Mass (Da):27,830
Last modified:October 1, 2000 - v1
Checksum:i033592FD0968EADB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250007 mRNA. Translation: CAB94710.1.
RefSeqiNP_001302558.1. NM_001315629.1.

Genome annotation databases

GeneIDi106621041.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiADH_BACOL
AccessioniPrimary (citable) accession number: Q9NAR7
Secondary accession number(s): P82461
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 4, 2001
Last sequence update: October 1, 2000
Last modified: May 10, 2017
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families