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Protein

40S ribosomal protein S4

Gene

rps-4

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-CEL-72702. Ribosomal scanning and start codon recognition.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S4
Gene namesi
Name:rps-4
ORF Names:Y43B11AR.4
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome IV

Organism-specific databases

WormBaseiY43B11AR.4; CE24278; WBGene00004473; rps-4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001308301 – 25940S ribosomal protein S4Add BLAST259

Proteomic databases

EPDiQ9N3X2.
PaxDbiQ9N3X2.
PeptideAtlasiQ9N3X2.
PRIDEiQ9N3X2.

PTM databases

iPTMnetiQ9N3X2.

Expressioni

Gene expression databases

BgeeiWBGene00004473.

Interactioni

Protein-protein interaction databases

BioGridi42600. 3 interactors.
DIPiDIP-24988N.
IntActiQ9N3X2. 2 interactors.
MINTiMINT-1080839.
STRINGi6239.Y43B11AR.4.1.

Structurei

3D structure databases

ProteinModelPortaliQ9N3X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 100S4 RNA-bindingAdd BLAST60

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS4 family.Sequence analysis

Phylogenomic databases

eggNOGiKOG0378. Eukaryota.
COG1471. LUCA.
GeneTreeiENSGT00390000005569.
HOGENOMiHOG000231325.
InParanoidiQ9N3X2.
KOiK02987.
OMAiRKDYKFP.
OrthoDBiEOG091G0MYF.
PhylomeDBiQ9N3X2.

Family and domain databases

Gene3Di3.10.290.10. 1 hit.
HAMAPiMF_00485. Ribosomal_S4e. 1 hit.
InterProiView protein in InterPro
IPR032277. 40S_S4_C.
IPR000876. Ribosomal_S4e.
IPR013845. Ribosomal_S4e_central_region.
IPR013843. Ribosomal_S4e_N.
IPR018199. Ribosomal_S4e_N_CS.
IPR036986. S4_RNA-bd_sf.
PANTHERiPTHR11581. PTHR11581. 1 hit.
PfamiView protein in Pfam
PF16121. 40S_S4_C. 1 hit.
PF00900. Ribosomal_S4e. 1 hit.
PF08071. RS4NT. 1 hit.
PIRSFiPIRSF002116. Ribosomal_S4. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD002667. Ribosomal_S4e_central. 1 hit.
PROSITEiView protein in PROSITE
PS00528. RIBOSOMAL_S4E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9N3X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGPKKHLKR LAAPSHWMLD KLGGVFAVRP NPGPHKLRES LPLSLFLRNR
60 70 80 90 100
LKYALNYTEA KKILTQRVVR VDGKVRTCHK FPTGFMDVVA IERTNEYFRM
110 120 130 140 150
LYDTKGRYVV HRIQAAEADF KLCKVKSVRT VNKGVPVLTT TDGRTIRYPD
160 170 180 190 200
PHVKVNDTIV FNISTQKITD SVKFEPGNLA YVTGGRNVGR VGIIGHRERL
210 220 230 240 250
PGASDIIHIK DSAGHSFATR ISNVFVIGKG NKALVSLPTG AGIRLSIAEE

RDKRMAQKH
Length:259
Mass (Da):29,044
Last modified:October 1, 2000 - v1
Checksum:i2A5CA98C640284E7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FO081794 Genomic DNA. Translation: CCD74049.1.
RefSeqiNP_501103.1. NM_068702.4.
UniGeneiCel.11997.

Genome annotation databases

EnsemblMetazoaiY43B11AR.4; Y43B11AR.4; WBGene00004473.
GeneIDi177481.
KEGGicel:CELE_Y43B11AR.4.
UCSCiY43B11AR.4.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiRS4_CAEEL
AccessioniPrimary (citable) accession number: Q9N3X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 1, 2000
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families