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Protein
Submitted name:

Interleukin-1 receptor type II

Gene

IL-1RII

Organism
Equus caballus (Horse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor type IIImported
Gene namesi
Name:IL-1RIIImported
OrganismiEquus caballus (Horse)Imported
Taxonomic identifieri9796 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaPerissodactylaEquidaeEquus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei347 – 368HelicalSequence analysisAdd BLAST22

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
ChainiPRO_500433072919 – 403Sequence analysisAdd BLAST385

Proteomic databases

PaxDbiQ9N2H5.

Interactioni

Protein-protein interaction databases

STRINGi9796.ENSECAP00000000293.

Structurei

3D structure databases

ProteinModelPortaliQ9N2H5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 124Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST113
Domaini150 – 225Ig-like (immunoglobulin-like)InterPro annotationAdd BLAST76

Keywords - Domaini

Immunoglobulin domainSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJCQ. Eukaryota.
ENOG410YQDP. LUCA.
HOGENOMiHOG000113036.
HOVERGENiHBG052104.
KOiK04387.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR004074. IL-1_rcpt_I/II-typ.
IPR004077. IL-1_rcpt_II-typ.
IPR013151. Immunoglobulin.
[Graphical view]
PfamiPF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01539. INTRLEUKN1R2.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9N2H5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPILYMLILG VPAFTIQPEE RTVTAGNCQF LGKHFKTDLM VEREPVVLRC
60 70 80 90 100
PQAWYRWLDS ASSHVNVTWR KNDSTRMVPE EEETRMWVQD NALWILPALQ
110 120 130 140 150
GDSGTYICTV RNASYCYEMS TELRVFEKTE AALTYISYPQ ILTLSTSGLL
160 170 180 190 200
VCPELSEFTR NKTDVEVQWY KDSVLLDQDN EKFLSVAGPP RLLVQNVSME
210 220 230 240 250
DAGYYSCVMT LIHNGTRVNI TRNIELRVQK RREETVPVIV SPRQTILASL
260 270 280 290 300
GSRLIIPCKV FLGAGTQWTT DLWWMANNTN IDIAYRGGRV TEGQRQEYSE
310 320 330 340 350
NNENYIEVPL IFDPVIREDL NTDFKCVTYN TRSFQTLHTT VKEAATFPWG
360 370 380 390 400
TVLAPLLLVF LVLGGIWMRN RCKHRRGKAY GLTALKIERQ VFQSYPSKIK

EIK
Length:403
Mass (Da):46,361
Last modified:October 1, 2000 - v1
Checksum:i79115D80D187180C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033415 mRNA. Translation: BAA94382.1.
RefSeqiNP_001075285.1. NM_001081816.1.
UniGeneiEca.12589.

Genome annotation databases

GeneIDi100033831.
KEGGiecb:100033831.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB033415 mRNA. Translation: BAA94382.1.
RefSeqiNP_001075285.1. NM_001081816.1.
UniGeneiEca.12589.

3D structure databases

ProteinModelPortaliQ9N2H5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9796.ENSECAP00000000293.

Proteomic databases

PaxDbiQ9N2H5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100033831.
KEGGiecb:100033831.

Organism-specific databases

CTDi7850.

Phylogenomic databases

eggNOGiENOG410IJCQ. Eukaryota.
ENOG410YQDP. LUCA.
HOGENOMiHOG000113036.
HOVERGENiHBG052104.
KOiK04387.

Family and domain databases

Gene3Di2.60.40.10. 2 hits.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR004074. IL-1_rcpt_I/II-typ.
IPR004077. IL-1_rcpt_II-typ.
IPR013151. Immunoglobulin.
[Graphical view]
PfamiPF00047. ig. 1 hit.
[Graphical view]
PRINTSiPR01539. INTRLEUKN1R2.
PR01536. INTRLKN1R12F.
SMARTiSM00409. IG. 3 hits.
SM00408. IGc2. 2 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 3 hits.
PROSITEiPS50835. IG_LIKE. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9N2H5_HORSE
AccessioniPrimary (citable) accession number: Q9N2H5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 1, 2000
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.