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Q9N295 (B3GT5_PANTR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-1,3-galactosyltransferase 5

Short name=Beta-1,3-GalTase 5
Short name=Beta3Gal-T5
Short name=Beta3GalT5
Short name=b3Gal-T5
EC=2.4.1.-
Alternative name(s):
Beta-3-Gx-T5
UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 5
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 5
Gene names
Name:B3GALT5
OrganismPan troglodytes (Chimpanzee) [Reference proteome]
Taxonomic identifier9598 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan

Protein attributes

Sequence length297 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of Gal to GlcNAc-based acceptors with a preference for the core3 O-linked glycan GlcNAc(beta1,3)GalNAc structure. Can use glycolipid LC3Cer as an efficient acceptor By similarity.

Pathway

Protein modification; protein glycosylation.

Subcellular location

Golgi apparatus membrane; Single-pass type II membrane protein Potential.

Sequence similarities

Belongs to the glycosyltransferase 31 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – ›297›297Beta-1,3-galactosyltransferase 5
PRO_0000219167

Regions

Topological domain1 – 77Cytoplasmic Potential
Transmembrane8 – 2821Helical; Signal-anchor for type II membrane protein; Potential
Topological domain29 – ›297›269Lumenal Potential

Amino acid modifications

Glycosylation1301N-linked (GlcNAc...) Potential
Glycosylation1741N-linked (GlcNAc...) Potential
Glycosylation2311N-linked (GlcNAc...) Potential

Experimental info

Non-terminal residue2971

Sequences

Sequence LengthMass (Da)Tools
Q9N295 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: BB7963250A837A28

FASTA29734,851
        10         20         30         40         50         60 
MAFPKMRLMY VCLLVLGALC VYFSMYSLNL FKEQSFVYKK DGNFLKLPDT DCRQTPPFLV 

        70         80         90        100        110        120 
LLVTSSHRQL AERMAIRQTW GKERTVKGKQ LKTFFLLGTT SSAAETKEVD QESQRHGDII 

       130        140        150        160        170        180 
QKDFLDVYYN LTLKTMMGIE WVHRFCPQAA FVMKTDSDMF INVDYLTELL LKKNRTTRFF 

       190        200        210        220        230        240 
TGFLKLNEFP IRQPFSKWFV SKSEYPWDRY PPFCSGTGYV FSGDVASQVY NVSESVPYIK 

       250        260        270        280        290 
LEDVFVGLCL ERLNIRLEEL HSQPTFFPGG LRFSVCRFRR IVACHFIKPR TLLDYWQ 

« Hide

References

[1]"Human-specific amino acid changes found in 103 protein-coding genes."
Kitano T., Liu Y.-H., Ueda S., Saitou N.
Mol. Biol. Evol. 21:936-944(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB041414 Genomic DNA. Translation: BAA94499.1.

3D structure databases

ProteinModelPortalQ9N295.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING9598.ENSPTRP00000053952.

Protein family/group databases

CAZyGT31. Glycosyltransferase Family 31.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGNOG293774.
HOGENOMHOG000059604.
HOVERGENHBG101817.
InParanoidQ9N295.

Enzyme and pathway databases

UniPathwayUPA00378.

Family and domain databases

InterProIPR002659. Glyco_trans_31.
[Graphical view]
PANTHERPTHR11214. PTHR11214. 1 hit.
PfamPF01762. Galactosyl_T. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB3GT5_PANTR
AccessionPrimary (citable) accession number: Q9N295
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways