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Protein

Mitochondrial carrier homolog 2

Gene

MTCH2

Organism
Bos taurus (Bovine)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

The substrate transported is not yet known. Induces mitochondrial depolarization (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial carrier homolog 2
Gene namesi
Name:MTCH2
OrganismiBos taurus (Bovine)
Taxonomic identifieri9913 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaRuminantiaPecoraBovidaeBovinaeBos
Proteomesi
  • UP000009136 Componenti: Unplaced

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei8 – 28HelicalSequence analysisAdd BLAST21
Transmembranei175 – 195HelicalSequence analysisAdd BLAST21
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000906362 – 303Mitochondrial carrier homolog 2Add BLAST302

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9N285.
PRIDEiQ9N285.

Interactioni

Protein-protein interaction databases

STRINGi9913.ENSBTAP00000024956.

Structurei

3D structure databases

ProteinModelPortaliQ9N285.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati2 – 98Solcar 1Add BLAST97
Repeati118 – 206Solcar 2Add BLAST89

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG2745. Eukaryota.
ENOG410XSXF. LUCA.
HOGENOMiHOG000231394.
HOVERGENiHBG058632.
InParanoidiQ9N285.

Family and domain databases

Gene3Di1.50.40.10. 1 hit.
InterProiView protein in InterPro
IPR018108. Mitochondrial_sb/sol_carrier.
IPR023395. Mt_carrier_dom.
PfamiView protein in Pfam
PF00153. Mito_carr. 1 hit.
SUPFAMiSSF103506. SSF103506. 1 hit.
PROSITEiView protein in PROSITE
PS50920. SOLCAR. 2 hits.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9N285-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADAASQVLL GSGLTILSQP LMYVKVLIQV GYEPLAPTVG RNIFGRQVCQ
60 70 80 90 100
LPGLFCYAQH IASIDGKRGL FTGLTPRLCS GILGTVVHGK VLQHYQECDK
110 120 130 140 150
AEESGSGNVQ KEVSSSFDRV IKETTREMMA RSAATLITHP FHVITLRSMV
160 170 180 190 200
QFIGRESKYC GLCDSIATIY REEGILGFFA GLIPRLLGDI ISLWLCNSLA
210 220 230 240 250
YLVNTYALDS GVSTMNEMKS YSQAVTGFFA SMLTYPFVLV SNLMAVNNCG
260 270 280 290 300
LAGGCPPYAP IYSSWIDCWC MLQKEGNMSR GNSLFFRKVP FGKTYCCDLR

MLI
Length:303
Mass (Da):33,294
Last modified:June 7, 2005 - v2
Checksum:i4DCC992C2265BD9F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti82I → V in BAA95942 (Ref. 1) Curated1
Sequence conflicti165S → F in BAA95942 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB042815 mRNA. Translation: BAA95942.1.
BT020931 mRNA. Translation: AAX08948.1.
UniGeneiBt.65563.

Similar proteinsi

Entry informationi

Entry nameiMTCH2_BOVIN
AccessioniPrimary (citable) accession number: Q9N285
Secondary accession number(s): Q5E9I9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: June 7, 2005
Last modified: February 15, 2017
This is version 88 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families