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Q9MUR4 (ODPB_MESVI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Pyruvate dehydrogenase E1 component subunit beta

EC=1.2.4.1
Gene names
Name:pdhB
Synonyms:odpB
Encoded onPlastid; Chloroplast
OrganismMesostigma viride (Green alga)
Taxonomic identifier41882 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaMesostigmatophyceaeMesostigmatalesMesostigmataceaeMesostigma

Protein attributes

Sequence length327 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.

Catalytic activity

Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.

Cofactor

Thiamine pyrophosphate.

Subunit structure

Heterodimer of an alpha and a beta chain By similarity.

Subcellular location

Plastidchloroplast.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentChloroplast
Plastid
   LigandPyruvate
Thiamine pyrophosphate
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentchloroplast

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionpyruvate dehydrogenase (acetyl-transferring) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 327327Pyruvate dehydrogenase E1 component subunit beta
PRO_0000162218

Sites

Binding site601Thiamine pyrophosphate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9MUR4 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 8E8D7CD1ADD64E5A

FASTA32736,005
        10         20         30         40         50         60 
MTVRFLFEAL NMAIDEEMAR NDKVALLGED IGHYGGSYKV TQNLYAKYGE HRVIDTPIAE 

        70         80         90        100        110        120 
NSFVGAAIGA AMTGLVTVVE GMNMGFILLA FSQISNNMGM LSATSGGHYH IPIVLRGPGG 

       130        140        150        160        170        180 
VGKQLGAEHS QRLECYFQSV PGLQIVACST PYNAKGLLKS AIRSKNPIFF LEHVLLYNLK 

       190        200        210        220        230        240 
AEVPDNDYVL PLEKAEIVRQ GNDITILTYS RMRYNVIQAV KVLVEKGYDP EIIDLISLKP 

       250        260        270        280        290        300 
FDIETIGKSI QKTHKVLIVE ESMMTGGISN VLQSLILENF FDDLDNRPMC LSSPNVPTPY 

       310        320 
SGPLEEVSIV QTADIIESVE QILTNKM 

« Hide

References

[1]"Ancestral chloroplast genome in Mesostigma viride reveals an early branch of green plant evolution."
Lemieux C., Otis C., Turmel M.
Nature 403:649-652(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: NIES-296.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF166114 Genomic DNA. Translation: AAF43837.1.
RefSeqNP_038396.1. NC_002186.1.

3D structure databases

ProteinModelPortalQ9MUR4.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID800962.

Family and domain databases

Gene3D3.40.50.920. 1 hit.
3.40.50.970. 1 hit.
InterProIPR029061. THDP-binding.
IPR009014. Transketo_C/Pyr-ferredox_oxred.
IPR005475. Transketolase-like_Pyr-bd.
IPR005476. Transketolase_C.
[Graphical view]
PfamPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
[Graphical view]
SMARTSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMSSF52518. SSF52518. 1 hit.
SSF52922. SSF52922. 1 hit.
ProtoNetSearch...

Entry information

Entry nameODPB_MESVI
AccessionPrimary (citable) accession number: Q9MUR4
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program