Q9MUR4 (ODPB_MESVI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Pyruvate dehydrogenase E1 component subunit beta
EC=1.2.4.1

Gene names

Name:	pdhB
Synonyms:	odpB

Encoded on

Plastid; Chloroplast

Organism

Mesostigma viride

Taxonomic identifier

41882 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Streptophyta › Mesostigmatophyceae › Mesostigmatales › Mesostigmataceae › Mesostigma

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3) By similarity.
Catalytic activity	Pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2.
Cofactor	Thiamine pyrophosphate.
Subunit structure	Heterodimer of an alpha and a beta chain By similarity.
Subcellular location	Plastid › chloroplast.

Ontologies

Keywords
Biological process	Glycolysis
Cellular component	Chloroplast Plastid
Ligand	Pyruvate Thiamine pyrophosphate
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	chloroplast Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	pyruvate dehydrogenase (acetyl-transferring) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Pyruvate dehydrogenase E1 component subunit beta		PRO_0000162218
Sites
	Binding site	60	1	Thiamine pyrophosphate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9MUR4 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 8E8D7CD1ADD64E5A	FASTA	327	36,005
	10 20 30 40 50 60 MTVRFLFEAL NMAIDEEMAR NDKVALLGED IGHYGGSYKV TQNLYAKYGE HRVIDTPIAE 70 80 90 100 110 120 NSFVGAAIGA AMTGLVTVVE GMNMGFILLA FSQISNNMGM LSATSGGHYH IPIVLRGPGG 130 140 150 160 170 180 VGKQLGAEHS QRLECYFQSV PGLQIVACST PYNAKGLLKS AIRSKNPIFF LEHVLLYNLK 190 200 210 220 230 240 AEVPDNDYVL PLEKAEIVRQ GNDITILTYS RMRYNVIQAV KVLVEKGYDP EIIDLISLKP 250 260 270 280 290 300 FDIETIGKSI QKTHKVLIVE ESMMTGGISN VLQSLILENF FDDLDNRPMC LSSPNVPTPY 310 320 SGPLEEVSIV QTADIIESVE QILTNKM

References

[1]	"Ancestral chloroplast genome in Mesostigma viride reveals an early branch of green plant evolution." Lemieux C., Otis C., Turmel M. Nature 403:649-652(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NIES-296.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF166114 Genomic DNA. Translation: AAF43837.1.
RefSeq	NP_038396.1. NC_002186.1.
3D structure databases
ProteinModelPortal	Q9MUR4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	800962.
Phylogenomic databases
ProtClustDB	CHL00144.
Family and domain databases
Gene3D	3.40.50.920. 1 hit.
InterPro	IPR009014. Transketo_C/Pyr-ferredox_oxred. IPR015941. Transketolase-like_C. IPR005475. Transketolase-like_Pyr-bd. IPR005476. Transketolase_C. [Graphical view]
Pfam	PF02779. Transket_pyr. 1 hit. PF02780. Transketolase_C. 1 hit. [Graphical view]
SMART	SM00861. Transket_pyr. 1 hit. [Graphical view]
SUPFAM	SSF52922. Transketo_C_like. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ODPB_MESVI

Accession

Primary (citable) accession number: Q9MUR4

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
Last sequence update:	October 1, 2000
Last modified:	April 3, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program