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Q9MBB1

- CHSY_EQUAR

UniProt

Q9MBB1 - CHSY_EQUAR

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Protein

Chalcone synthase

Gene

CHS

Organism
Equisetum arvense (Field horsetail) (Common horsetail)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei170 – 1701PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase
Gene namesi
Name:CHS
OrganismiEquisetum arvense (Field horsetail) (Common horsetail)
Taxonomic identifieri3258 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaMoniliformopsesEquisetidaeEquisetalesEquisetaceaeEquisetum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 405405Chalcone synthasePRO_0000215975Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9MBB1.
SMRiQ9MBB1. Positions 11-403.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9MBB1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTVLEESADA SSRRLAQRAN GPATVLAIGT ANPANVFEQS SYPDFYFDIT
60 70 80 90 100
NSQHMTELKL KFSRMCQKSG IKKRYMHLNS EILKANPSLC AYWEKSLDVR
110 120 130 140 150
QDIAVVEVPK LGKEASLKAI KEWGQPKSKI THLVFCTTSG VDMPGADWAL
160 170 180 190 200
TKLLGLRPSV KRLMMYQQGC FAGGTVLRVA KDVAENNKGA RVLVVCSEIT
210 220 230 240 250
CVTFRGPSET HLDSLVGQAL FGDGAAAVIL GSDPLPEENP CFELHWSGSN
260 270 280 290 300
ILPDSDGAID GHLREVGLTF HLMKDVPGII SKNIGKVLND AFRSAFDESG
310 320 330 340 350
NAEDRPASVN DIFWIAHPGG PAILDQVEEK MKLAPEKMRA TRDVLSEYGN
360 370 380 390 400
MSSACVLFIM DHMRRMSAQN KLQTTGEGLD WGVLLGFGPG LTVETVLLKS

IRLAC
Length:405
Mass (Da):44,216
Last modified:October 1, 2000 - v1
Checksum:iF20F5701381813A5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030004 mRNA. Translation: BAA89501.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB030004 mRNA. Translation: BAA89501.1 .

3D structure databases

ProteinModelPortali Q9MBB1.
SMRi Q9MBB1. Positions 11-403.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Yamazaki Y., Sankawa U.
    Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiCHSY_EQUAR
AccessioniPrimary (citable) accession number: Q9MBB1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: October 1, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3