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Q9MBB1 (CHSY_EQUAR) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase
Gene names
Name:CHS
OrganismEquisetum arvense (Field horsetail) (Common horsetail)
Taxonomic identifier3258 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaMoniliformopsesEquisetopsidaEquisetalesEquisetaceaeEquisetum

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Chalcone synthase
PRO_0000215975

Sites

Active site1701 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9MBB1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: F20F5701381813A5

FASTA40544,216
        10         20         30         40         50         60 
MTVLEESADA SSRRLAQRAN GPATVLAIGT ANPANVFEQS SYPDFYFDIT NSQHMTELKL 

        70         80         90        100        110        120 
KFSRMCQKSG IKKRYMHLNS EILKANPSLC AYWEKSLDVR QDIAVVEVPK LGKEASLKAI 

       130        140        150        160        170        180 
KEWGQPKSKI THLVFCTTSG VDMPGADWAL TKLLGLRPSV KRLMMYQQGC FAGGTVLRVA 

       190        200        210        220        230        240 
KDVAENNKGA RVLVVCSEIT CVTFRGPSET HLDSLVGQAL FGDGAAAVIL GSDPLPEENP 

       250        260        270        280        290        300 
CFELHWSGSN ILPDSDGAID GHLREVGLTF HLMKDVPGII SKNIGKVLND AFRSAFDESG 

       310        320        330        340        350        360 
NAEDRPASVN DIFWIAHPGG PAILDQVEEK MKLAPEKMRA TRDVLSEYGN MSSACVLFIM 

       370        380        390        400 
DHMRRMSAQN KLQTTGEGLD WGVLLGFGPG LTVETVLLKS IRLAC 

« Hide

References

[1]Yamazaki Y., Sankawa U.
Submitted (JUL-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB030004 mRNA. Translation: BAA89501.1.

3D structure databases

ProteinModelPortalQ9MBB1.
SMRQ9MBB1. Positions 11-403.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHSY_EQUAR
AccessionPrimary (citable) accession number: Q9MBB1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: October 16, 2013
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways