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Reviewed, UniProtKB/Swiss-Prot Q9MB95 (1A11_PRUMU)

Last modified February 9, 2010. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    1-aminocyclopropane-1-carboxylate synthase 1
      Short name=ACC synthase 1
    EC=4.4.1.14
Alternative name(s):
    S-adenosyl-L-methionine methylthioadenosine-lyase
Gene names
Name: ACS1
OrganismPrunus mume (Japanese flowering apricot)
Taxonomic identifier102107 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidsfabidsRosalesRosaceaeAmygdaloideaePrunus

Protein attributes

Sequence length492 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

General annotation (Comments)

Function

Catalyzes the formation of 1-aminocyclopropane-1-carboxylate, a direct precursor of ethylene in higher plants.

Catalytic activity

S-adenosyl-L-methionine = 1-aminocyclopropane-1-carboxylate + methylthioadenosine.

Cofactor

Pyridoxal phosphate.

Pathway

Alkene biosynthesis; ethylene biosynthesis via S-adenosyl-L-methionine; ethylene from S-adenosyl-L-methionine: step 1/2.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4924921-aminocyclopropane-1-carboxylate synthase 1
PRO_0000123918

Amino acid modifications

Modified residue2771N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9MB95-1 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 2002047AF2B43D89

FASTA49255,066
        10         20         30         40         50         60 
MGSSSATANR FLLSKIATSE GHGENSPYFD GWKAYDRNPF HPTKNPEGVI QMGLAENQLS 

        70         80         90        100        110        120 
FDSIEDWIKK NPKASICTPE GVEEFKNVAI FQDYHGFPEF RKAVAMFMSK ARGGRVTFDP 

       130        140        150        160        170        180 
NRVVMSGGAT GANELVMFCL ADPGDAFLVP SPYYPAFFRD LGWRTGVQIV PVDCDSSNNF 

       190        200        210        220        230        240 
KITKEALEAA YEKAQKNNIN VKGLIITNPS NPLGTTLDRN TLESLVEFIN QKNIHLVCDE 

       250        260        270        280        290        300 
IYAATVFSSP TFTCISEVIQ NMNCNPNLIH IVYSLSKDMG LPGLRVGIVY SYNDDVVNIG 

       310        320        330        340        350        360 
RKMSSFGLVS SQTQHMLPSM LLDEEFVARF LETSPKRLAK RHGVFTKGLE EVGINCLKSN 

       370        380        390        400        410        420 
AGLFCWMDLR RLLEDQTFDG EMVLWRVIVN EVGPNVSPGS SFKCVEPGWF RVCFANMDDE 

       430        440        450        460        470        480 
TLEVALKRIR TFVRQGKKAQ DQVVQVKSPK RWKSNLRLSF SSSSTRRFDQ ESVNVLSPHM 

       490 
MSPHSPLVRA KT 

« Hide

References

[1]"Expression of ACC synthase is enhanced earlier than that of ACC oxidase during fruit ripening of mume (Prunus mume)."
Mita S., Kirita C., Kato M., Hyodo H.
Physiol. Plantarum 107:319-328(1999)
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB031026 mRNA. Translation: BAA90549.1.

3D structure databases

SMRQ9MB95. Positions 12-433.
ModBaseSearch...

Enzyme and pathway databases

BRENDA4.4.1.14. 278032.

Family and domain databases

InterProIPR001176. ACC_synthase.
IPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase_major_dom.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
Gene3DG3DSA:3.40.640.10. PyrdxlP-dep_Trfase_major_sub1. 1 hit.
G3DSA:3.90.1150.10. PyrdxlP-dep_Trfase_major_sub2. 1 hit.
PfamPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
PRINTSPR00753. ACCSYNTHASE.
PROSITEPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry name1A11_PRUMU
AccessionPrimary (citable) accession number: Q9MB95
Entry history
Integrated into UniProtKB/Swiss-Prot: November 2, 2001
Last sequence update: October 1, 2000
Last modified: February 9, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents