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Q9MB40

- CHS3_IPOBA

UniProt

Q9MB40 - CHS3_IPOBA

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Protein

Chalcone synthase LF3

Gene

CHS-LF3

Organism
Ipomoea batatas (Sweet potato) (Convolvulus batatas)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase LF3 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase LF3
Gene namesi
Name:CHS-LF3
OrganismiIpomoea batatas (Sweet potato) (Convolvulus batatas)
Taxonomic identifieri4120 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 388388Chalcone synthase LF3PRO_0000215985Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9MB40.
SMRiQ9MB40. Positions 3-386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9MB40-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVTVGEVRKA QRAEGPATIL AIGTATPANC VNQSTYPDYY FRITNSEHKT
60 70 80 90 100
ELKEKFQRMC DKSMITKRYM HLTEEILKEN PSFCEYMAPS LDARQDIAVV
110 120 130 140 150
EVPKLGKEAA QSAIKGWGQP KSKITHVVFC TTSGVDMPGA DYQLTKLLGL
160 170 180 190 200
RPSVKRLMMY QQGCFAGGTV LRLAKDLAEN NKGARVLIVC SEITVVTFRG
210 220 230 240 250
PSEAHLDSLV GQALFGDGAA AVIVGADPTP AEKPLFQLVS AAQTLAPDSC
260 270 280 290 300
GAIDGHLREV GLTFHLLKDV PSVVSNNIEK CLFEAFNPLG ISDWNSVFWI
310 320 330 340 350
AHPGGPAILD QVEDKLGLKP EKLRATRHVL SEYGNMSSAC VLFILDEMRK
360 370 380
ASSNDGLGTT GEGLEWGVLF GFGPGLTIET VVLHSVPT
Length:388
Mass (Da):42,011
Last modified:October 1, 2000 - v1
Checksum:i7BB7A06EFD184F9A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB037389 mRNA. Translation: BAA90328.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB037389 mRNA. Translation: BAA90328.1 .

3D structure databases

ProteinModelPortali Q9MB40.
SMRi Q9MB40. Positions 3-386.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Hsu T.-J., Morita H., Shiokawa K., Noguchi H.
    Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiCHS3_IPOBA
AccessioniPrimary (citable) accession number: Q9MB40
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: October 1, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3