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Q9MB40 (CHS3_IPOBA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase LF3

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase LF3
Gene names
Name:CHS-LF3
OrganismIpomoea batatas (Sweet potato) (Convolvulus batatas)
Taxonomic identifier4120 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesConvolvulaceaeIpomoeeaeIpomoea

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 388388Chalcone synthase LF3
PRO_0000215985

Sites

Active site1641 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9MB40 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 7BB7A06EFD184F9A

FASTA38842,011
        10         20         30         40         50         60 
MVTVGEVRKA QRAEGPATIL AIGTATPANC VNQSTYPDYY FRITNSEHKT ELKEKFQRMC 

        70         80         90        100        110        120 
DKSMITKRYM HLTEEILKEN PSFCEYMAPS LDARQDIAVV EVPKLGKEAA QSAIKGWGQP 

       130        140        150        160        170        180 
KSKITHVVFC TTSGVDMPGA DYQLTKLLGL RPSVKRLMMY QQGCFAGGTV LRLAKDLAEN 

       190        200        210        220        230        240 
NKGARVLIVC SEITVVTFRG PSEAHLDSLV GQALFGDGAA AVIVGADPTP AEKPLFQLVS 

       250        260        270        280        290        300 
AAQTLAPDSC GAIDGHLREV GLTFHLLKDV PSVVSNNIEK CLFEAFNPLG ISDWNSVFWI 

       310        320        330        340        350        360 
AHPGGPAILD QVEDKLGLKP EKLRATRHVL SEYGNMSSAC VLFILDEMRK ASSNDGLGTT 

       370        380 
GEGLEWGVLF GFGPGLTIET VVLHSVPT 

« Hide

References

[1]Hsu T.-J., Morita H., Shiokawa K., Noguchi H.
Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AB037389 mRNA. Translation: BAA90328.1.

3D structure databases

ProteinModelPortalQ9MB40.
SMRQ9MB40. Positions 3-386.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHS3_IPOBA
AccessionPrimary (citable) accession number: Q9MB40
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways