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Protein

Putative vesicle-associated membrane protein 726

Gene

VAMP726

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-8856825. Cargo recognition for clathrin-mediated endocytosis.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative vesicle-associated membrane protein 726
Short name:
AtVAMP726
Gene namesi
Name:VAMP726
Ordered Locus Names:At1g04760
ORF Names:F13M7.25
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRilocus:2010627. AT1G04760.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 196CytoplasmicSequence analysisAdd BLAST196
Transmembranei197 – 217Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST21
Topological domaini218 – 220VesicularSequence analysis3

GO - Cellular componenti

  • chloroplast Source: TAIR
  • early endosome membrane Source: UniProtKB-SubCell
  • endosome Source: TAIR
  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
  • SNARE complex Source: GO_Central

Keywords - Cellular componenti

Cell membrane, Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002067591 – 220Putative vesicle-associated membrane protein 726Add BLAST220

Proteomic databases

PaxDbiQ9MAS5.

Expressioni

Tissue specificityi

Expressed in flowers, leaves, stems and roots.1 Publication

Gene expression databases

GenevisibleiQ9MAS5. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi24659. 3 interactors.
STRINGi3702.AT1G04760.1.

Structurei

3D structure databases

ProteinModelPortaliQ9MAS5.
SMRiQ9MAS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 114LonginPROSITE-ProRule annotationAdd BLAST105
Domaini130 – 190v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9MAS5.
KOiK08511.
OMAiIEKTIHR.
OrthoDBiEOG09360NHL.
PhylomeDBiQ9MAS5.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiView protein in InterPro
IPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
PfamiView protein in Pfam
PF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiView protein in SMART
SM01270. Longin. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9MAS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGQQSLIYSF VARGTVILAE YTEFKGNFTS VAAQCLQKLP SSNNKFTYNC
60 70 80 90 100
DGHTFNYLAD NGFTYCVVVI ESAGRQIPMA FLERVKEDFN KRYGGGKAST
110 120 130 140 150
AKANSLNKEF GSKLKEHMQY CADHPEEISK LSKVKAQVTE VKGVMMENIE
160 170 180 190 200
KVLDRGEKIE LLVDKTENLR SQAQDFRTQG TKMKRKLWFE NMKIKLIVFG
210 220
IIVALILIII LSVCHGFKCT
Length:220
Mass (Da):24,873
Last modified:May 10, 2005 - v2
Checksum:iF8D984AC0F118548
GO

Sequence cautioni

The sequence AAF40460 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004809 Genomic DNA. Translation: AAF40460.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27740.1.
PIRiF86180.
RefSeqiNP_001323352.1. NM_001331501.1.
NP_171968.1. NM_100354.2.

Genome annotation databases

EnsemblPlantsiAT1G04760.1; AT1G04760.1; AT1G04760.
AT1G04760.2; AT1G04760.2; AT1G04760.
GeneIDi839424.
GrameneiAT1G04760.1; AT1G04760.1; AT1G04760.
AT1G04760.2; AT1G04760.2; AT1G04760.
KEGGiath:AT1G04760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004809 Genomic DNA. Translation: AAF40460.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE27740.1.
PIRiF86180.
RefSeqiNP_001323352.1. NM_001331501.1.
NP_171968.1. NM_100354.2.

3D structure databases

ProteinModelPortaliQ9MAS5.
SMRiQ9MAS5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi24659. 3 interactors.
STRINGi3702.AT1G04760.1.

Proteomic databases

PaxDbiQ9MAS5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G04760.1; AT1G04760.1; AT1G04760.
AT1G04760.2; AT1G04760.2; AT1G04760.
GeneIDi839424.
GrameneiAT1G04760.1; AT1G04760.1; AT1G04760.
AT1G04760.2; AT1G04760.2; AT1G04760.
KEGGiath:AT1G04760.

Organism-specific databases

AraportiAT1G04760.
TAIRilocus:2010627. AT1G04760.

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9MAS5.
KOiK08511.
OMAiIEKTIHR.
OrthoDBiEOG09360NHL.
PhylomeDBiQ9MAS5.

Enzyme and pathway databases

ReactomeiR-ATH-8856825. Cargo recognition for clathrin-mediated endocytosis.

Miscellaneous databases

PROiQ9MAS5.

Gene expression databases

GenevisibleiQ9MAS5. AT.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiView protein in InterPro
IPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
PfamiView protein in Pfam
PF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiView protein in SMART
SM01270. Longin. 1 hit.
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiView protein in PROSITE
PS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiVA726_ARATH
AccessioniPrimary (citable) accession number: Q9MAS5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: May 10, 2005
Last modified: March 15, 2017
This is version 114 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.