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Q9MAQ3 (UBP11_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative ubiquitin carboxyl-terminal hydrolase 11

EC=3.4.19.12
Alternative name(s):
Deubiquitinating enzyme 11
Short name=AtUBP11
Ubiquitin thioesterase 11
Ubiquitin-specific-processing protease 11
Gene names
Name:UBP11
Ordered Locus Names:At1g32850
ORF Names:F9L11.5
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length892 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins By similarity.

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).

Sequence similarities

Belongs to the peptidase C19 family.

Contains 1 DUSP domain.

Contains 1 USP domain.

Sequence caution

The sequence AAF31287.1 differs from that shown. Reason: Erroneous gene model prediction.

Ontologies

Keywords
   Biological processUbl conjugation pathway
   Molecular functionHydrolase
Protease
Thiol protease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processubiquitin-dependent protein catabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionubiquitin-specific protease activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 892892Putative ubiquitin carboxyl-terminal hydrolase 11
PRO_0000313038

Regions

Domain17 – 132116DUSP
Domain301 – 880580USP

Sites

Active site3101Nucleophile By similarity
Active site8381Proton acceptor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9MAQ3 [UniParc].

Last modified January 15, 2008. Version 2.
Checksum: 8377D6A44BD26A67

FASTA892101,175
        10         20         30         40         50         60 
MTLITDSESI GVCESSYTPE EERRIVTELN NEAEADLKEG NLYFVISNRW YTRWQRFVGL 

        70         80         90        100        110        120 
LTEEFRSGEP SEVTRPGPID NHDIIDSESD ASDPQLRMML EEGVDYTLVQ QEVWRKLVKW 

       130        140        150        160        170        180 
YKGGPPVPRK LISQGFYTKS FSVEVYLLCL TLTDSRDEST TIIRLSKQAS IGQLYEMVCA 

       190        200        210        220        230        240 
GKGVAKEKAR IWDYFEKKKS VLLDPSSEQS VEEAGLQFNQ DILLEVDGSA SSQFVMSLAE 

       250        260        270        280        290        300 
NELAMVPLEP MRSDAMDIVR GGGTLSNGHS NGFKFSFFGR NTFKDDVSSR TFGKGEKRGL 

       310        320        330        340        350        360 
GGLQNLGNTC FMNSTLQCLA HTPPIVEYFL QDYRSDINAK NPLGMRGELA IAFGELLRKL 

       370        380        390        400        410        420 
WSSGQNTVAP RAFKTKLARF APQFSGYNQH DSQEMLAFLL DGLHEDLNKV KRKPYIEAKD 

       430        440        450        460        470        480 
SDGRPDDEVA EEKWKYHKAR NDSVIVDVFQ GQYKSTLVCP DCGKISITFD PFMYLSLPLP 

       490        500        510        520        530        540 
SSRTRSMTVT VFYGDGSHLP MPYTVTVPKD GSCRDLSNAL GTACCLDNDE SLLLAEVYDH 

       550        560        570        580        590        600 
KVFKYYENPR ELLNGIKDNE HIVAYRFKQM HKGPGKVKLE ILHGEQEKSS DRGPKCFGTP 

       610        620        630        640        650        660 
LVTYINKEPL SGTDIATSIS GLLSPLRRVH MSCVVNSGNE NGHVPDESSR SILSRDTETE 

       670        680        690        700        710        720 
DNDRELSLSL LRDYYSFNLQ PLESDSVVNP GSVTKVLVKW NEKEHEKYDS SYLNDLPKVH 

       730        740        750        760        770        780 
KNVLAKKTMQ EGISLFSCLE AFLAEEPLGP DDMWYCPGCK EHRQANKKLD LWKLPDILVF 

       790        800        810        820        830        840 
HLKRFTYSRY FKNKIDTLVN FHIHDLDLSK YVKNEDGQSY LYELYAISNH YGGLGGGHYT 

       850        860        870        880        890 
AYAKLMDETK WYNFDDSRVS AVNESEIKTS AAYVLFYQRV KSDSETSDMK MD 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"The ubiquitin-specific protease family from Arabidopsis. AtUBP1 and 2 are required for the resistance to the amino acid analog canavanine."
Yan N., Doelling J.H., Falbel T.G., Durski A.M., Vierstra R.D.
Plant Physiol. 124:1828-1843(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY ORGANIZATION, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC006424 Genomic DNA. Translation: AAF31287.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE31532.1.
PIRC86453.
RefSeqNP_174562.2. NM_103019.2.
UniGeneAt.51891.

3D structure databases

ProteinModelPortalQ9MAQ3.
SMRQ9MAQ3. Positions 27-225, 299-480, 626-885.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G32850.1-P.

Protein family/group databases

MEROPSC19.A04.

Proteomic databases

PRIDEQ9MAQ3.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G32850.1; AT1G32850.1; AT1G32850.
GeneID840179.
KEGGath:AT1G32850.

Organism-specific databases

TAIRAT1G32850.

Phylogenomic databases

eggNOGCOG5560.
HOGENOMHOG000264375.
InParanoidQ9MAQ3.
KOK11835.
OMARDTETED.
PhylomeDBQ9MAQ3.

Enzyme and pathway databases

BioCycARA:AT1G32850-MONOMER.

Gene expression databases

GenevestigatorQ9MAQ3.

Family and domain databases

Gene3D3.30.2230.10. 1 hit.
InterProIPR006615. Pept_C19_DUSP.
IPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR028889. UCH/PAN2.
[Graphical view]
PfamPF06337. DUSP. 1 hit.
PF00443. UCH. 1 hit.
[Graphical view]
SMARTSM00695. DUSP. 1 hit.
[Graphical view]
SUPFAMSSF143791. SSF143791. 1 hit.
PROSITEPS51283. DUSP. 1 hit.
PS00972. USP_1. 1 hit.
PS00973. USP_2. 1 hit.
PS50235. USP_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBP11_ARATH
AccessionPrimary (citable) accession number: Q9MAQ3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: January 15, 2008
Last modified: June 11, 2014
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names