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Protein

Probable protein phosphatase 2C 34

Gene

At3g05640

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi98Manganese 1By similarity1
Metal bindingi98Manganese 2By similarity1
Metal bindingi99Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi294Manganese 2By similarity1
Metal bindingi340Manganese 2By similarity1

GO - Molecular functioni

GO - Biological processi

  • negative regulation of growth Source: TAIR
  • protein dephosphorylation Source: TAIR
  • regulation of microtubule binding Source: TAIR
  • response to water deprivation Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Enzyme and pathway databases

ReactomeiR-ATH-70895 Branched-chain amino acid catabolism

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 34 (EC:3.1.3.16)
Short name:
AtPP2C34
Gene namesi
Ordered Locus Names:At3g05640
ORF Names:F18C1.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G05640
TAIRilocus:2078117 AT3G05640

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679611 – 358Probable protein phosphatase 2C 34Add BLAST358

Proteomic databases

PaxDbiQ9M9W9

Expressioni

Gene expression databases

ExpressionAtlasiQ9M9W9 baseline and differential
GenevisibleiQ9M9W9 AT

Interactioni

Protein-protein interaction databases

BioGridi5066, 4 interactors
IntActiQ9M9W9, 5 interactors
MINTiQ9M9W9
STRINGi3702.AT3G05640.1

Structurei

3D structure databases

ProteinModelPortaliQ9M9W9
SMRiQ9M9W9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini62 – 349PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST288

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi351 – 357Poly-Ser7

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233897
InParanoidiQ9M9W9
OMAiRHISIRD
OrthoDBiEOG09360GNF
PhylomeDBiQ9M9W9

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9M9W9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGHFSSMFNG IARSFSIKKA KNINSSKSYA KEATDEMARE AKKKELILRS
60 70 80 90 100
SGCINADGSN NLASVFSRRG EKGVNQDCAI VWEGYGCQED MIFCGIFDGH
110 120 130 140 150
GPWGHFVSKQ VRNSMPISLL CNWKETLSQT TIAEPDKELQ RFAIWKYSFL
160 170 180 190 200
KTCEAVDLEL EHHRKIDSFN SGTTALTIVR QGDVIYIANV GDSRAVLATV
210 220 230 240 250
SDEGSLVAVQ LTVDFKPNLP QEEERIIGCN GRVFCLQDEP GVHRVWQPVD
260 270 280 290 300
ESPGLAMSRA FGDYCIKDYG LVSVPEVTQR HISIRDQFII LATDGVWDVI
310 320 330 340 350
SNQEAIDIVS STAERAKAAK RLVQQAVRAW NRKRRGIAMD DISAVCLFFH

SSSSSPSL
Length:358
Mass (Da):39,780
Last modified:October 1, 2000 - v1
Checksum:i3B11400CD38E254A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC011620 Genomic DNA Translation: AAF26133.1
CP002686 Genomic DNA Translation: AEE74270.1
CP002686 Genomic DNA Translation: AEE74271.1
CP002686 Genomic DNA Translation: ANM64837.1
AY050388 mRNA Translation: AAK91405.1
AY093799 mRNA Translation: AAM10415.1
AK316795 mRNA Translation: BAH19512.1
RefSeqiNP_001326841.1, NM_001337595.1
NP_187215.1, NM_111437.3
NP_974230.1, NM_202501.3
UniGeneiAt.26583
At.70680

Genome annotation databases

EnsemblPlantsiAT3G05640.1; AT3G05640.1; AT3G05640
AT3G05640.2; AT3G05640.2; AT3G05640
AT3G05640.3; AT3G05640.3; AT3G05640
GeneIDi819731
GrameneiAT3G05640.1; AT3G05640.1; AT3G05640
AT3G05640.2; AT3G05640.2; AT3G05640
AT3G05640.3; AT3G05640.3; AT3G05640
KEGGiath:AT3G05640

Similar proteinsi

Entry informationi

Entry nameiP2C34_ARATH
AccessioniPrimary (citable) accession number: Q9M9W9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health