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Q9M9H6 (CK1_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable choline kinase 1

Short name=AtCK1
EC=2.7.1.32
Gene names
Name:CK1
Synonyms:CK
Ordered Locus Names:At1g71697
ORF Names:F14O23.8, F26A9.3
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length346 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Involved in phospholipid biosynthesis. Catalyzes the first step in phosphatidylcholine biosynthesis By similarity.

Catalytic activity

ATP + choline = ADP + phosphocholine.

Pathway

Phospholipid metabolism; phosphatidylcholine biosynthesis; phosphocholine from choline: step 1/1.

Tissue specificity

Expressed in roots. Expressed at low levels in cauline leaves and flowers. Ref.5

Induction

By wounding, and salt and osmotic stresses. Ref.5 Ref.6

Sequence similarities

Belongs to the choline/ethanolamine kinase family.

Sequence caution

The sequence AAG51828.1 differs from that shown. Reason: Erroneous gene model prediction.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 346346Probable choline kinase 1
PRO_0000423346

Sites

Binding site731ATP By similarity
Binding site2101ATP By similarity
Binding site2271ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9M9H6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 3FABBAAAB09B5597

FASTA34640,016
        10         20         30         40         50         60 
MAIKTKTSLI PSCSSPEDLK RVLQTLGSSW GDVVEDLERL EVVPLKGAMT NEVYQINWPT 

        70         80         90        100        110        120 
LNGEDVHRKV LVRIYGDGVD LFFNRGDEIK TFECMSHHGY GPKLLGRFSD GRLEEFIHAR 

       130        140        150        160        170        180 
TLSADDLRVA ETSDFIAAKL REFHKLDMPG PKNVLLWERL RTWLKEAKNL ASPIEMDKYR 

       190        200        210        220        230        240 
LEGLENEINL LEERLTRDDQ EIGFCHNDLQ YGNVMIDEVT NAITIIDYEY SSFNPIAYDI 

       250        260        270        280        290        300 
ANHFCEMAAN YHSDTPHVLD YTLYPGEGER RRFISTYLGS TGNATSDKEV ERLLKDAESY 

       310        320        330        340 
TLANHIFWGL WGIISGHVNK IEFDYMEYAR QRFEQYWLRK PLLLEG 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. expand/collapse author list , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Empirical analysis of transcriptional activity in the Arabidopsis genome."
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. expand/collapse author list , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[5]"Jasmonic acid-dependent and -independent signaling pathways control wound-induced gene activation in Arabidopsis thaliana."
Titarenko E., Rojo E., Leon J., Sanchez-Serrano J.J.
Plant Physiol. 115:817-826(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: TISSUE SPECIFICITY, INDUCTION BY WOUNDING.
[6]"Regulation of phosphatidylcholine biosynthesis under salt stress involves choline kinases in Arabidopsis thaliana."
Tasseva G., Richard L., Zachowski A.
FEBS Lett. 566:115-120(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: INDUCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC012654 Genomic DNA. Translation: AAF43223.1.
AC016163 Genomic DNA. Translation: AAG51828.1. Sequence problems.
CP002684 Genomic DNA. Translation: AEE35220.1.
BT008311 mRNA. Translation: AAP37670.1.
AK229787 mRNA. Translation: BAF01619.1.
AK230407 mRNA. Translation: BAF02205.1.
PIRC96739.
RefSeqNP_177315.1. NM_105828.3.
UniGeneAt.43278.

3D structure databases

ProteinModelPortalQ9M9H6.
SMRQ9M9H6. Positions 24-340.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT1G71697.1-P.

Proteomic databases

PRIDEQ9M9H6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT1G71697.1; AT1G71697.1; AT1G71697.
GeneID843500.
KEGGath:AT1G71697.

Organism-specific databases

TAIRAT1G71697.

Phylogenomic databases

HOGENOMHOG000041274.
InParanoidQ9M9H6.
KOK14156.
OMAEFDYMEY.
PhylomeDBQ9M9H6.

Enzyme and pathway databases

BioCycARA:AT1G71697-MONOMER.
UniPathwayUPA00753; UER00737.

Gene expression databases

ArrayExpressQ9M9H6.
GenevestigatorQ9M9H6.

Family and domain databases

InterProIPR026712. Cho/Etha_kinase.
IPR007521. Choline_kin_N.
IPR011009. Kinase-like_dom.
[Graphical view]
PANTHERPTHR22603:SF32. PTHR22603:SF32. 1 hit.
PfamPF04428. Choline_kin_N. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCK1_ARATH
AccessionPrimary (citable) accession number: Q9M9H6
Secondary accession number(s): Q9C9J3
Entry history
Integrated into UniProtKB/Swiss-Prot: September 18, 2013
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names