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Protein

Probable protein phosphatase 2C 15

Gene

At1g68410

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi78 – 781Manganese 1By similarity
Metal bindingi78 – 781Manganese 2By similarity
Metal bindingi79 – 791Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi254 – 2541Manganese 2By similarity
Metal bindingi293 – 2931Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G68410-MONOMER.
ARA:GQT-2522-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 15 (EC:3.1.3.16)
Short name:
AtPP2C15
Gene namesi
Ordered Locus Names:At1g68410
ORF Names:T2E12.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 1

Organism-specific databases

TAIRiAT1G68410.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 436436Probable protein phosphatase 2C 15PRO_0000367946Add
BLAST

Proteomic databases

PRIDEiQ9M9C6.

Expressioni

Gene expression databases

ExpressionAtlasiQ9M9C6. baseline and differential.
GenevestigatoriQ9M9C6.

Interactioni

Protein-protein interaction databases

BioGridi28391. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ9M9C6.
SMRiQ9M9C6. Positions 45-304.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini30 – 302273PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000240114.
InParanoidiQ9M9C6.
OMAiCSDCRDK.
PhylomeDBiQ9M9C6.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M9C6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASREGKRRN HNHDDEKLVP LAALISRETK AAKMEKPIVR FGQAAQSRKG
60 70 80 90 100
EDYVLIKTDS LRVPSNSSTA FSVFAVFDGH NGKAAAVYTR ENLLNHVISA
110 120 130 140 150
LPSGLSRDEW LHALPRALVS GFVKTDKEFQ SRGETSGTTA TFVIVDGWTV
160 170 180 190 200
TVACVGDSRC ILDTKGGSVS NLTVDHRLED NTEERERVTA SGGEVGRLSI
210 220 230 240 250
VGGVEIGPLR CWPGGLCLSR SIGDMDVGEF IVPVPFVKQV KLSNLGGRLI
260 270 280 290 300
IASDGIWDAL SSEVAAKTCR GLSAELAARQ VVKEALRRRG LKDDTTCIVV
310 320 330 340 350
DIIPPENFQE PPPSPPKKHN NFFKSLLFRK KSNSSNKLSK KLSTVGIVEE
360 370 380 390 400
LFEEGSAMLA ERLGSGDCSK ESTTGGGIFT CAICQLDLAP SEGISVHAGS
410 420 430
IFSTSLKPWQ GPFLCTDCRD KKDAMEGKRP SGVKVI
Length:436
Mass (Da):47,041
Last modified:September 30, 2000 - v1
Checksum:iF24CE21FBC283252
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015986 Genomic DNA. Translation: AAF26041.1.
CP002684 Genomic DNA. Translation: AEE34790.1.
CP002684 Genomic DNA. Translation: AEE34791.1.
AY050881 mRNA. Translation: AAK92818.1.
AY091295 mRNA. Translation: AAM14234.1.
PIRiA96708.
RefSeqiNP_001031252.1. NM_001036175.1.
NP_177008.1. NM_105512.2.
UniGeneiAt.26552.

Genome annotation databases

EnsemblPlantsiAT1G68410.1; AT1G68410.1; AT1G68410.
AT1G68410.2; AT1G68410.2; AT1G68410.
GeneIDi843170.
KEGGiath:AT1G68410.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC015986 Genomic DNA. Translation: AAF26041.1.
CP002684 Genomic DNA. Translation: AEE34790.1.
CP002684 Genomic DNA. Translation: AEE34791.1.
AY050881 mRNA. Translation: AAK92818.1.
AY091295 mRNA. Translation: AAM14234.1.
PIRiA96708.
RefSeqiNP_001031252.1. NM_001036175.1.
NP_177008.1. NM_105512.2.
UniGeneiAt.26552.

3D structure databases

ProteinModelPortaliQ9M9C6.
SMRiQ9M9C6. Positions 45-304.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi28391. 1 interaction.

Proteomic databases

PRIDEiQ9M9C6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G68410.1; AT1G68410.1; AT1G68410.
AT1G68410.2; AT1G68410.2; AT1G68410.
GeneIDi843170.
KEGGiath:AT1G68410.

Organism-specific databases

TAIRiAT1G68410.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000240114.
InParanoidiQ9M9C6.
OMAiCSDCRDK.
PhylomeDBiQ9M9C6.

Enzyme and pathway databases

BioCyciARA:AT1G68410-MONOMER.
ARA:GQT-2522-MONOMER.

Gene expression databases

ExpressionAtlasiQ9M9C6. baseline and differential.
GenevestigatoriQ9M9C6.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
    Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
    , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
    Nature 408:816-820(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  2. The Arabidopsis Information Resource (TAIR)
    Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  3. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C15_ARATH
AccessioniPrimary (citable) accession number: Q9M9C6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 13, 2009
Last sequence update: September 30, 2000
Last modified: March 31, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.