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Protein

Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC

Gene

SEC

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

O-linked N-acetylglucosamine transferase (OGT) that mediates O-glycosylation of capsid protein (CP) of virus in case of infection by Plum pox virus. OGTs catalyze the addition of nucleotide-activated sugars directly onto the polypeptide through O-glycosidic linkage with the hydroxyl of serine or threonine. Probably acts by adding O-linked sugars to yet unknown proteins. Its OGT activity has been proved in vitro but not in vivo. Required with SPY for gamete and seed development.1 Publication

Catalytic activityi

UDP-N-acetyl-D-glucosamine + peptide = UDP + N-acetyl-beta-D-glucosaminyl-peptide.1 Publication

Pathwayi: protein glycosylation

This protein is involved in the pathway protein glycosylation, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein glycosylation and in Protein modification.

GO - Molecular functioni

  • transferase activity, transferring glycosyl groups Source: TAIR

GO - Biological processi

  • multicellular organism development Source: UniProtKB-KW
  • protein O-linked glycosylation Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Developmental protein, Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciARA:AT3G04240-MONOMER.
BRENDAi2.4.1.255. 399.
UniPathwayiUPA00378.

Protein family/group databases

CAZyiGT41. Glycosyltransferase Family 41.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC (EC:2.4.1.-)
Alternative name(s):
Protein SECRET AGENT
Gene namesi
Name:SEC
Ordered Locus Names:At3g04240
ORF Names:T6K12.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G04240.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 977977Probable UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SECPRO_0000191782Add
BLAST

Proteomic databases

PaxDbiQ9M8Y0.
PRIDEiQ9M8Y0.

Expressioni

Gene expression databases

ExpressionAtlasiQ9M8Y0. baseline and differential.
GenevisibleiQ9M8Y0. AT.

Interactioni

Protein-protein interaction databases

BioGridi4914. 4 interactions.
IntActiQ9M8Y0. 2 interactions.
MINTiMINT-8060306.
STRINGi3702.AT3G04240.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M8Y0.
SMRiQ9M8Y0. Positions 24-965.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati53 – 8634TPR 1Add
BLAST
Repeati87 – 12034TPR 2Add
BLAST
Repeati121 – 15434TPR 3Add
BLAST
Repeati155 – 18834TPR 4Add
BLAST
Repeati190 – 22233TPR 5Add
BLAST
Repeati223 – 25634TPR 6Add
BLAST
Repeati257 – 29034TPR 7Add
BLAST
Repeati292 – 32433TPR 8Add
BLAST
Repeati325 – 35834TPR 9Add
BLAST
Repeati360 – 39233TPR 10Add
BLAST
Repeati393 – 42634TPR 11Add
BLAST
Repeati428 – 46033TPR 12Add
BLAST
Repeati461 – 49434TPR 13Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni495 – 977483Catalytic regionAdd
BLAST

Sequence similaritiesi

Contains 13 TPR repeats.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

eggNOGiENOG410IRRE. Eukaryota.
COG3914. LUCA.
HOGENOMiHOG000003765.
InParanoidiQ9M8Y0.
KOiK09667.
OMAiKLAYMPN.
OrthoDBiEOG093601AY.
PhylomeDBiQ9M8Y0.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
InterProiIPR029489. OGT/SEC/SPY_C.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF13844. Glyco_transf_41. 2 hits.
PF00515. TPR_1. 2 hits.
PF13414. TPR_11. 1 hit.
PF13176. TPR_7. 1 hit.
PF13181. TPR_8. 2 hits.
[Graphical view]
SMARTiSM00028. TPR. 13 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS50005. TPR. 13 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M8Y0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISSKNGAAM ISRPVFLSDR VDEVFSRKLD LSVSSSSSSS LLQQFNKTHE
60 70 80 90 100
GDDDARLALA HQLYKGGDFK QALEHSNMVY QRNPLRTDNL LLIGAIYYQL
110 120 130 140 150
QEYDMCIARN EEALRIQPQF AECYGNMANA WKEKGDTDRA IRYYLIAIEL
160 170 180 190 200
RPNFADAWSN LASAYMRKGR LSEATQCCQQ ALSLNPLLVD AHSNLGNLMK
210 220 230 240 250
AQGLIHEAYS CYLEAVRIQP TFAIAWSNLA GLFMESGDLN RALQYYKEAV
260 270 280 290 300
KLKPAFPDAY LNLGNVYKAL GRPTEAIMCY QHALQMRPNS AMAFGNIASI
310 320 330 340 350
YYEQGQLDLA IRHYKQALSR DPRFLEAYNN LGNALKDIGR VDEAVRCYNQ
360 370 380 390 400
CLALQPNHPQ AMANLGNIYM EWNMMGPASS LFKATLAVTT GLSAPFNNLA
410 420 430 440 450
IIYKQQGNYS DAISCYNEVL RIDPLAADAL VNRGNTYKEI GRVTEAIQDY
460 470 480 490 500
MHAINFRPTM AEAHANLASA YKDSGHVEAA ITSYKQALLL RPDFPEATCN
510 520 530 540 550
LLHTLQCVCC WEDRSKMFAE VESIIRRQIN MSVLPSVQPF HAIAYPIDPI
560 570 580 590 600
LALEISRKYA AHCSIIASRF GLPPFTHPAG LPVKREGGFK RLRIGYVSSD
610 620 630 640 650
FGNHPLSHLM GSVFGMHNRE NVEVFCYALS ANDNTEWRQR IQSEAEHFLD
660 670 680 690 700
VSAMSSDAIA KIINQDKIQI LINLNGYTKG ARNEIFAMQP APIQVSYMGF
710 720 730 740 750
PGTTGATYID YLVTDEFVSP LQYAHIYSEK LVHLPHCYFV NDYKQKNQDV
760 770 780 790 800
LDPNSKPKRS DYGLPEDKFI FACFNQLYKM DPEIVNTWCN ILKRVPNSAL
810 820 830 840 850
WLLRFPAAGE MRFRTYAAAQ GVQPDQIIFT DVAMKSEHIR RSVLADVILD
860 870 880 890 900
TPLCNGHTTG TDVLWAGVPM ITLPLEKMAT RVAGSLCLAT GLGHGMIVNS
910 920 930 940 950
LEEYEEKAVS LALNKPKLQA LTKELRASRL TCPLFDTMRW VKNLERSYFK
960 970
MWNLHCSGQQ PQHFKVLEND LEFPHDR
Length:977
Mass (Da):110,114
Last modified:October 1, 2000 - v1
Checksum:i2AC617CB4B6D5409
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF441079 mRNA. Translation: AAL60196.1.
AC016829 Genomic DNA. Translation: AAF26789.1.
CP002686 Genomic DNA. Translation: AEE74056.1.
AY090938 mRNA. Translation: AAM13988.1.
AY117340 mRNA. Translation: AAM51415.1.
RefSeqiNP_187074.1. NM_111295.3.
UniGeneiAt.27850.
At.71305.

Genome annotation databases

EnsemblPlantsiAT3G04240.1; AT3G04240.1; AT3G04240.
GeneIDi819579.
GrameneiAT3G04240.1; AT3G04240.1; AT3G04240.
KEGGiath:AT3G04240.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF441079 mRNA. Translation: AAL60196.1.
AC016829 Genomic DNA. Translation: AAF26789.1.
CP002686 Genomic DNA. Translation: AEE74056.1.
AY090938 mRNA. Translation: AAM13988.1.
AY117340 mRNA. Translation: AAM51415.1.
RefSeqiNP_187074.1. NM_111295.3.
UniGeneiAt.27850.
At.71305.

3D structure databases

ProteinModelPortaliQ9M8Y0.
SMRiQ9M8Y0. Positions 24-965.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4914. 4 interactions.
IntActiQ9M8Y0. 2 interactions.
MINTiMINT-8060306.
STRINGi3702.AT3G04240.1.

Protein family/group databases

CAZyiGT41. Glycosyltransferase Family 41.

Proteomic databases

PaxDbiQ9M8Y0.
PRIDEiQ9M8Y0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G04240.1; AT3G04240.1; AT3G04240.
GeneIDi819579.
GrameneiAT3G04240.1; AT3G04240.1; AT3G04240.
KEGGiath:AT3G04240.

Organism-specific databases

TAIRiAT3G04240.

Phylogenomic databases

eggNOGiENOG410IRRE. Eukaryota.
COG3914. LUCA.
HOGENOMiHOG000003765.
InParanoidiQ9M8Y0.
KOiK09667.
OMAiKLAYMPN.
OrthoDBiEOG093601AY.
PhylomeDBiQ9M8Y0.

Enzyme and pathway databases

UniPathwayiUPA00378.
BioCyciARA:AT3G04240-MONOMER.
BRENDAi2.4.1.255. 399.

Miscellaneous databases

PROiQ9M8Y0.

Gene expression databases

ExpressionAtlasiQ9M8Y0. baseline and differential.
GenevisibleiQ9M8Y0. AT.

Family and domain databases

Gene3Di1.25.40.10. 4 hits.
InterProiIPR029489. OGT/SEC/SPY_C.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom.
IPR001440. TPR_1.
IPR019734. TPR_repeat.
[Graphical view]
PfamiPF13844. Glyco_transf_41. 2 hits.
PF00515. TPR_1. 2 hits.
PF13414. TPR_11. 1 hit.
PF13176. TPR_7. 1 hit.
PF13181. TPR_8. 2 hits.
[Graphical view]
SMARTiSM00028. TPR. 13 hits.
[Graphical view]
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiPS50005. TPR. 13 hits.
PS50293. TPR_REGION. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiSEC_ARATH
AccessioniPrimary (citable) accession number: Q9M8Y0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.