true
2012-03-21
2024-01-24
133
DUS1B_ARATH
Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.
Salanoubat M.
Lemcke K.
Rieger M.
Ansorge W.
Unseld M.
Fartmann B.
Valle G.
Bloecker H.
Perez-Alonso M.
Obermaier B.
Delseny M.
Boutry M.
Grivell L.A.
Mache R.
Puigdomenech P.
De Simone V.
Choisne N.
Artiguenave F.
Robert C.
Brottier P.
Wincker P.
Cattolico L.
Weissenbach J.
Saurin W.
Quetier F.
Schaefer M.
Mueller-Auer S.
Gabel C.
Fuchs M.
Benes V.
Wurmbach E.
Drzonek H.
Erfle H.
Jordan N.
Bangert S.
Wiedelmann R.
Kranz H.
Voss H.
Holland R.
Brandt P.
Nyakatura G.
Vezzi A.
D'Angelo M.
Pallavicini A.
Toppo S.
Simionati B.
Conrad A.
Hornischer K.
Kauer G.
Loehnert T.-H.
Nordsiek G.
Reichelt J.
Scharfe M.
Schoen O.
Bargues M.
Terol J.
Climent J.
Navarro P.
Collado C.
Perez-Perez A.
Ottenwaelder B.
Duchemin D.
Cooke R.
Laudie M.
Berger-Llauro C.
Purnelle B.
Masuy D.
de Haan M.
Maarse A.C.
Alcaraz J.-P.
Cottet A.
Casacuberta E.
Monfort A.
Argiriou A.
Flores M.
Liguori R.
Vitale D.
Mannhaupt G.
Haase D.
Schoof H.
Rudd S.
Zaccaria P.
Mewes H.-W.
Mayer K.F.X.
Kaul S.
Town C.D.
Koo H.L.
Tallon L.J.
Jenkins J.
Rooney T.
Rizzo M.
Walts A.
Utterback T.
Fujii C.Y.
Shea T.P.
Creasy T.H.
Haas B.
Maiti R.
Wu D.
Peterson J.
Van Aken S.
Pai G.
Militscher J.
Sellers P.
Gill J.E.
Feldblyum T.V.
Preuss D.
Lin X.
Nierman W.C.
Salzberg S.L.
White O.
Venter J.C.
Fraser C.M.
Kaneko T.
Nakamura Y.
Sato S.
Kato T.
Asamizu E.
Sasamoto S.
Kimura T.
Idesawa K.
Kawashima K.
Kishida Y.
Kiyokawa C.
Kohara M.
Matsumoto M.
Matsuno A.
Muraki A.
Nakayama S.
Nakazaki N.
Shinpo S.
Takeuchi C.
Wada T.
Watanabe A.
Yamada M.
Yasuda M.
Tabata S.
doi:10.1038/35048706
2000
Nature
408
820-822
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
cv. Columbia
Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.
Cheng C.Y.
Krishnakumar V.
Chan A.P.
Thibaud-Nissen F.
Schobel S.
Town C.D.
doi:10.1111/tpj.13415
2017
Plant J.
89
789-804
GENOME REANNOTATION
Functional annotation of a full-length Arabidopsis cDNA collection.
Seki M.
Narusaka M.
Kamiya A.
Ishida J.
Satou M.
Sakurai T.
Nakajima M.
Enju A.
Akiyama K.
Oono Y.
Muramatsu M.
Hayashizaki Y.
Kawai J.
Carninci P.
Itoh M.
Ishii Y.
Arakawa T.
Shibata K.
Shinagawa A.
Shinozaki K.
doi:10.1126/science.1071006
2002
Science
296
141-145
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Yamada K.
Lim J.
Dale J.M.
Chen H.
Shinn P.
Palm C.J.
Southwick A.M.
Wu H.C.
Kim C.J.
Nguyen M.
Pham P.K.
Cheuk R.F.
Karlin-Newmann G.
Liu S.X.
Lam B.
Sakano H.
Wu T.
Yu G.
Miranda M.
Quach H.L.
Tripp M.
Chang C.H.
Lee J.M.
Toriumi M.J.
Chan M.M.
Tang C.C.
Onodera C.S.
Deng J.M.
Akiyama K.
Ansari Y.
Arakawa T.
Banh J.
Banno F.
Bowser L.
Brooks S.Y.
Carninci P.
Chao Q.
Choy N.
Enju A.
Goldsmith A.D.
Gurjal M.
Hansen N.F.
Hayashizaki Y.
Johnson-Hopson C.
Hsuan V.W.
Iida K.
Karnes M.
Khan S.
Koesema E.
Ishida J.
Jiang P.X.
Jones T.
Kawai J.
Kamiya A.
Meyers C.
Nakajima M.
Narusaka M.
Seki M.
Sakurai T.
Satou M.
Tamse R.
Vaysberg M.
Wallender E.K.
Wong C.
Yamamura Y.
Yuan S.
Shinozaki K.
Davis R.W.
Theologis A.
Ecker J.R.
doi:10.1126/science.1088305
2003
Science
302
842-846
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
Full-length cDNA from Arabidopsis thaliana.
Brover V.V.
Troukhan M.E.
Alexandrov N.A.
Lu Y.-P.
Flavell R.B.
Feldmann K.A.
2002-03
EMBL/GenBank/DDBJ
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
Arabidopsis MAPK phosphatase 2 (MKP2) positively regulates oxidative stress tolerance and inactivates the MPK3 and MPK6 MAPKs.
Lee J.S.
Ellis B.E.
doi:10.1074/jbc.m701888200
2007
J. Biol. Chem.
282
25020-25029
FUNCTION AS PHOSPHATASE
SUBCELLULAR LOCATION
MUTAGENESIS OF CYS-109
MAPK phosphatase MKP2 mediates disease responses in Arabidopsis and functionally interacts with MPK3 and MPK6.
Lumbreras V.
Vilela B.
Irar S.
Sole M.
Capellades M.
Valls M.
Coca M.
Pages M.
doi:10.1111/j.1365-313x.2010.04297.x
2010
Plant J.
63
1017-1030
FUNCTION IN DEFENSE RESPONSE
INTERACTION WITH MPK3 AND MPK6
SUBCELLULAR LOCATION
TISSUE SPECIFICITY
DEVELOPMENTAL STAGE
DISRUPTION PHENOTYPE
Regulation of MAPK signaling and cell death by MAPK phosphatase MKP2.
Vilela B.
Pages M.
Lumbreras V.
doi:10.4161/psb.5.11.13645
2010
Plant Signal. Behav.
5
1497-1500
FUNCTION
INTERACTION WITH MPK6
MUTAGENESIS OF CYS-109
INDUCTION BY STRESS CONDITIONS
2
MKP2
Eukaryota
baseline and differential
DSP
Protein tyrosine phosphatase superfamily
Dual-sp_phosphatase_cat-dom
Prot-tyrosine_phosphatase-like
Tyr_Pase_dom
TYR_PHOSPHATASE_DUAL_dom
DUAL SPECIFICITY PROTEIN PHOSPHATASE
DUAL SPECIFICITY PROTEIN PHOSPHATASE 1B
DSPc
DSPc
(Phosphotyrosine protein) phosphatases II
TYR_PHOSPHATASE_2
TYR_PHOSPHATASE_DUAL
AT
Dual specificity protein phosphatase 1B
AtDsPTP1B
3.1.3.16
3.1.3.48
MAPK phosphatase 2
AtMKP2
DSPTP1B
MKP2
At3g06110
F28L1.5
Has a dual specificity toward Ser/Thr and Tyr-containing proteins. Prevents biotic and abiotic stress responses, including ozone, oxidative stress and pathogen attacks; represses MAPK activities during hypersensitive response to limit the spread of the HR response after infection by necrotrophic pathogen such as Botrytis cinerea. May be also involved in ABA and salt responses. Dephosphorylates MPK3 and MPK6.
Associates with MPK3 and MPK6. Interacts with MPK6 is promoted during HR-like responses triggered by fungal elicitors, whereas interaction with MPK3 in repressed.
Upon fungal elicitation, relocalizes surrounding spherical structures that could correspond to epiplasts.
Expressed in flowers, seedlings, roots, leaves, and seeds. Present in stomata and meristematic cells.
In flowers, expressed in stigmatic papillae, anthers, pollen grains and floral abscission zones. As flowers mature, progressively restricted to the abscission zones and the septum of the siliques. During seed development Mainly detected in seeds endosperm layer until the fourth day after germination. In young seedlings, confined to the cotyledons. Later observed in roots, especially in vascular organs and at branching points of lateral roots. In adult leaves, particularly localized in vascular tissues and hydathodes; mostly present in both young and senescent leaves, tissues undergoing developmental transitions.
Accumulates in response to stress conditions caused by abscisic acid (ABA) or salt treatment.
Delayed wilting symptoms in response to Ralstonia solanacearum and, by contrast, acceleration of disease progression during Botrytis cinerea infection, suggesting that this phosphatase plays differential functions in biotrophic versus necrotrophic pathogen-induced responses. Prolonged MPK3 and MPK6 activation during ozone treatment.
Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.
Dual specificity protein phosphatase 1B
18431
1
167
Tyrosine-protein phosphatase
24
165
Phosphocysteine intermediate
109
In isoform 2.
77
86
Loss of phosphatase activity.
S
2000-10-01
1
18431
180b93535443bfee36be25b262e9e6f3
1
MEKVVDLFGVGEANSQKLLEGGKDLSEIQQGLFIGSVAEANNKDFLKSSNITHVLTVAVALAPPYPDDFVYKVIEVVDRSETDLTVYFDECYSFIDQAIQSGGGVLVHCFMGMSRSVTIVVAYLMKKHGMGFSKAMELVRSRRHQAYPNPGFISQLQQFEKSIQGNA
2
MEKVVDLFGVGEANSQKLLEGGKDLSEIQQGLFIGSVAEANNKDFLKSSNITHVLTVAVALAPPYPDDFVYKVIEVYFDECYSFIDQAIQSGGGVLVHCFMGMSRSVTIVVAYLMKKHGMGFSKAMELVRSRRHQAYPNPGFISQLQQFEKSIQGNA
true
true
true
true
true
true
true
true
true
true
true
true