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Protein

T-complex protein 1 subunit zeta 1

Gene

CCT6A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.Curated

GO - Molecular functioni

GO - Biological processi

  • protein folding Source: InterPro
  • response to cadmium ion Source: TAIR
  • response to zinc ion Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-ATH-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit zeta 11 Publication
Short name:
TCP-1-zeta 11 Publication
Alternative name(s):
CCT-zeta 11 Publication
Chaperonin CCT6ACurated
Gene namesi
Name:CCT6ACurated
Ordered Locus Names:At3g02530Imported
ORF Names:F16B3.16Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G02530.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: TAIR
  • cytosol Source: TAIR
  • membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004316621 – 535T-complex protein 1 subunit zeta 1Add BLAST535

Proteomic databases

PaxDbiQ9M888.
PRIDEiQ9M888.

Expressioni

Gene expression databases

GenevisibleiQ9M888. AT.

Interactioni

Subunit structurei

Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.1 Publication

Protein-protein interaction databases

STRINGi3702.AT3G02530.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M888.
SMRiQ9M888.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0359. Eukaryota.
ENOG410XQ3Q. LUCA.
HOGENOMiHOG000226733.
InParanoidiQ9M888.
KOiK09498.
OMAiNDNSFVI.
OrthoDBiEOG0936070N.
PhylomeDBiQ9M888.

Family and domain databases

CDDicd03342. TCP1_zeta. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012722. Chap_CCT_zeta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PANTHERiPTHR11353:SF21. PTHR11353:SF21. 1 hit.
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02347. chap_CCT_zeta. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M888-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVRVLNPNA EVLNKSAALH MTINAAKGLQ DVLKSNLGPK GTIKMLVGGS
60 70 80 90 100
GDIKLTKDGN TLLKEMQIQN PTAIMIARTA VAQDDISGDG TTSTVIFIGE
110 120 130 140 150
LMKQSERCID EGMHPRVLVD GFEIAKRATL QFLDTFKTPV VMGDEPDKEI
160 170 180 190 200
LKMVARTTLR TKLYEGLADQ LTDIVVNSVL CIRKPQEPID LFMVEIMHMR
210 220 230 240 250
HKFDVDTRLV EGLVLDHGSR HPDMKRRAEN CHILTCNVSL EYEKSEINAG
260 270 280 290 300
FFYSNAEQRE AMVTAERRSV DERVQKIIEL KNKVCAGNDN SFVILNQKGI
310 320 330 340 350
DPPSLDLLAR EGIIALRRAK RRNMERLVLA CGGEAVNSVD DLTPDCLGWA
360 370 380 390 400
GLVYEHVLGE EKYTFVEQVK NPHSCTILIK GPNDHTIAQI KDAVRDGLRS
410 420 430 440 450
VKNTLEDECV VLGAGAFEVA ARQHLINEVK KTVQGRAQLG VEAFANALLV
460 470 480 490 500
VPKTLAENAG LDTQDVIISL TSEHDKGNIV GLDLQDGEPV DPQLAGIFDN
510 520 530
YSVKRQLINS GPVIASQLLL VDEVIRAGRN MRKPT
Length:535
Mass (Da):58,950
Last modified:October 1, 2000 - v1
Checksum:iCE624E390DD399E8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti17A → T in AAK62448 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021640 Genomic DNA. Translation: AAF32460.1.
CP002686 Genomic DNA. Translation: AEE73823.1.
AY062729 mRNA. Translation: AAL32807.1.
AY114652 mRNA. Translation: AAM47971.1.
BT001156 mRNA. Translation: AAN65043.1.
AF387003 mRNA. Translation: AAK62448.1.
AY084739 mRNA. Translation: AAM61312.1.
RefSeqiNP_186902.1. NM_111120.3.
UniGeneiAt.20380.
At.67357.

Genome annotation databases

EnsemblPlantsiAT3G02530.1; AT3G02530.1; AT3G02530.
GeneIDi821160.
GrameneiAT3G02530.1; AT3G02530.1; AT3G02530.
KEGGiath:AT3G02530.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021640 Genomic DNA. Translation: AAF32460.1.
CP002686 Genomic DNA. Translation: AEE73823.1.
AY062729 mRNA. Translation: AAL32807.1.
AY114652 mRNA. Translation: AAM47971.1.
BT001156 mRNA. Translation: AAN65043.1.
AF387003 mRNA. Translation: AAK62448.1.
AY084739 mRNA. Translation: AAM61312.1.
RefSeqiNP_186902.1. NM_111120.3.
UniGeneiAt.20380.
At.67357.

3D structure databases

ProteinModelPortaliQ9M888.
SMRiQ9M888.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G02530.1.

Proteomic databases

PaxDbiQ9M888.
PRIDEiQ9M888.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G02530.1; AT3G02530.1; AT3G02530.
GeneIDi821160.
GrameneiAT3G02530.1; AT3G02530.1; AT3G02530.
KEGGiath:AT3G02530.

Organism-specific databases

TAIRiAT3G02530.

Phylogenomic databases

eggNOGiKOG0359. Eukaryota.
ENOG410XQ3Q. LUCA.
HOGENOMiHOG000226733.
InParanoidiQ9M888.
KOiK09498.
OMAiNDNSFVI.
OrthoDBiEOG0936070N.
PhylomeDBiQ9M888.

Enzyme and pathway databases

ReactomeiR-ATH-390471. Association of TriC/CCT with target proteins during biosynthesis.
R-ATH-6814122. Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding.

Miscellaneous databases

PROiQ9M888.

Gene expression databases

GenevisibleiQ9M888. AT.

Family and domain databases

CDDicd03342. TCP1_zeta. 1 hit.
Gene3Di1.10.560.10. 2 hits.
3.30.260.10. 2 hits.
3.50.7.10. 1 hit.
InterProiIPR012722. Chap_CCT_zeta.
IPR017998. Chaperone_TCP-1.
IPR002194. Chaperonin_TCP-1_CS.
IPR002423. Cpn60/TCP-1.
IPR027409. GroEL-like_apical_dom.
IPR027413. GROEL-like_equatorial.
IPR027410. TCP-1-like_intermed.
[Graphical view]
PANTHERiPTHR11353:SF21. PTHR11353:SF21. 1 hit.
PfamiPF00118. Cpn60_TCP1. 1 hit.
[Graphical view]
PRINTSiPR00304. TCOMPLEXTCP1.
SUPFAMiSSF52029. SSF52029. 1 hit.
TIGRFAMsiTIGR02347. chap_CCT_zeta. 1 hit.
PROSITEiPS00750. TCP1_1. 1 hit.
PS00751. TCP1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTCPZA_ARATH
AccessioniPrimary (citable) accession number: Q9M888
Secondary accession number(s): Q8LFN3, Q94EZ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 7, 2015
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 132 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.