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Protein

T-complex protein 1 subunit zeta 1

Gene

CCT6A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.Curated

GO - Molecular functioni

GO - Biological processi

  • 'de novo' protein folding Source: GO_Central
  • chaperone-mediated protein folding Source: GO_Central
  • response to cadmium ion Source: TAIR
  • response to zinc ion Source: TAIR

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-390471 Association of TriC/CCT with target proteins during biosynthesis
R-ATH-6814122 Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Names & Taxonomyi

Protein namesi
Recommended name:
T-complex protein 1 subunit zeta 11 Publication
Short name:
TCP-1-zeta 11 Publication
Alternative name(s):
CCT-zeta 11 Publication
Chaperonin CCT6ACurated
Gene namesi
Name:CCT6ACurated
Ordered Locus Names:At3g02530Imported
ORF Names:F16B3.16Imported
OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G02530
TAIRilocus:2076924 AT3G02530

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004316621 – 535T-complex protein 1 subunit zeta 1Add BLAST535

Proteomic databases

PaxDbiQ9M888
PRIDEiQ9M888

Expressioni

Gene expression databases

ExpressionAtlasiQ9M888 baseline and differential
GenevisibleiQ9M888 AT

Interactioni

Subunit structurei

Heterooligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

STRINGi3702.AT3G02530.1

Structurei

3D structure databases

ProteinModelPortaliQ9M888
SMRiQ9M888
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0359 Eukaryota
ENOG410XQ3Q LUCA
HOGENOMiHOG000226733
InParanoidiQ9M888
KOiK09498
OMAiRQFIEDR
OrthoDBiEOG0936070N
PhylomeDBiQ9M888

Family and domain databases

CDDicd03342 TCP1_zeta, 1 hit
Gene3Di1.10.560.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR012722 Chap_CCT_zeta
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
PANTHERiPTHR11353 PTHR11353, 1 hit
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02347 chap_CCT_zeta, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9M888-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVRVLNPNA EVLNKSAALH MTINAAKGLQ DVLKSNLGPK GTIKMLVGGS
60 70 80 90 100
GDIKLTKDGN TLLKEMQIQN PTAIMIARTA VAQDDISGDG TTSTVIFIGE
110 120 130 140 150
LMKQSERCID EGMHPRVLVD GFEIAKRATL QFLDTFKTPV VMGDEPDKEI
160 170 180 190 200
LKMVARTTLR TKLYEGLADQ LTDIVVNSVL CIRKPQEPID LFMVEIMHMR
210 220 230 240 250
HKFDVDTRLV EGLVLDHGSR HPDMKRRAEN CHILTCNVSL EYEKSEINAG
260 270 280 290 300
FFYSNAEQRE AMVTAERRSV DERVQKIIEL KNKVCAGNDN SFVILNQKGI
310 320 330 340 350
DPPSLDLLAR EGIIALRRAK RRNMERLVLA CGGEAVNSVD DLTPDCLGWA
360 370 380 390 400
GLVYEHVLGE EKYTFVEQVK NPHSCTILIK GPNDHTIAQI KDAVRDGLRS
410 420 430 440 450
VKNTLEDECV VLGAGAFEVA ARQHLINEVK KTVQGRAQLG VEAFANALLV
460 470 480 490 500
VPKTLAENAG LDTQDVIISL TSEHDKGNIV GLDLQDGEPV DPQLAGIFDN
510 520 530
YSVKRQLINS GPVIASQLLL VDEVIRAGRN MRKPT
Length:535
Mass (Da):58,950
Last modified:October 1, 2000 - v1
Checksum:iCE624E390DD399E8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti17A → T in AAK62448 (PubMed:14593172).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC021640 Genomic DNA Translation: AAF32460.1
CP002686 Genomic DNA Translation: AEE73823.1
AY062729 mRNA Translation: AAL32807.1
AY114652 mRNA Translation: AAM47971.1
BT001156 mRNA Translation: AAN65043.1
AF387003 mRNA Translation: AAK62448.1
AY084739 mRNA Translation: AAM61312.1
RefSeqiNP_186902.1, NM_111120.3
UniGeneiAt.20380
At.67357

Genome annotation databases

EnsemblPlantsiAT3G02530.1; AT3G02530.1; AT3G02530
GeneIDi821160
GrameneiAT3G02530.1; AT3G02530.1; AT3G02530
KEGGiath:AT3G02530

Similar proteinsi

Entry informationi

Entry nameiTCPZA_ARATH
AccessioniPrimary (citable) accession number: Q9M888
Secondary accession number(s): Q8LFN3, Q94EZ9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 7, 2015
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 142 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health