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Protein

Cycloeucalenol cycloisomerase

Gene

CPI1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Converts pentacyclic cyclopropyl sterols to tetracyclic sterols.

Catalytic activityi

Cycloeucalenol = obtusifoliol.

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciARA:AT5G50375-MONOMER.
ARA:GQT-272-MONOMER.
MetaCyc:AT5G50375-MONOMER.
BRENDAi5.5.1.9. 399.

Names & Taxonomyi

Protein namesi
Recommended name:
Cycloeucalenol cycloisomerase (EC:5.5.1.9)
Alternative name(s):
Cycloeucalenol--obtusifoliol isomerase
Cyclopropyl sterol isomerase
Gene namesi
Name:CPI1
Ordered Locus Names:At5g50375
ORF Names:MXI22.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

TAIRiAT5G50375.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei22 – 4221HelicalSequence analysisAdd
BLAST
Transmembranei53 – 7321HelicalSequence analysisAdd
BLAST
Transmembranei89 – 10921HelicalSequence analysisAdd
BLAST
Transmembranei167 – 18721HelicalSequence analysisAdd
BLAST
Transmembranei201 – 22121HelicalSequence analysisAdd
BLAST
Transmembranei244 – 26421HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 280280Cycloeucalenol cycloisomerasePRO_0000089422Add
BLAST

Proteomic databases

PaxDbiQ9M643.
PRIDEiQ9M643.

PTM databases

iPTMnetiQ9M643.

Expressioni

Gene expression databases

ExpressionAtlasiQ9M643. baseline and differential.
GenevisibleiQ9M643. AT.

Interactioni

Protein-protein interaction databases

BioGridi20351. 6 interactions.
STRINGi3702.AT5G50375.2.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IHJA. Eukaryota.
ENOG410YNGH. LUCA.
HOGENOMiHOG000243779.
InParanoidiQ9M643.
OMAiQSGLPWF.
PhylomeDBiQ9M643.

Family and domain databases

InterProiIPR020532. Cycloeucalenol_cycloisomerase.
[Graphical view]
ProDomiPD317471. Cycloeucalenol_cycloisomerase. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

This entry describes 1 isoform i produced by alternative splicing. AlignAdd to basket

Note: A number of isoforms are produced. According to EST sequences.

Isoform 1 (identifier: Q9M643-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSGSSSPSLW LAPNPSKRWG ELFFLFYTPF WLTLCLGIVV PYKLYETFTE
60 70 80 90 100
LEYLLLALVS AVPAFVIPML LVGKADRSLC WKDRYWVKAN LWIIVFSYVG
110 120 130 140 150
NYFWTHYFFK VLGASYTFPS WKMNNVPHTT FFLTHVCFLF YHVASNITLR
160 170 180 190 200
RLRHSTADLP DSLKWCFEAA WILALSYFIA YLETIAIANF PYYEFVDRSA
210 220 230 240 250
MYRVGCLFYA IYFIVSFPMF FRMDEKSTDE WDLSRVAVDA LGAAMLVTII
260 270 280
LDLWRLFLGP IVPLPEGQNC LQSGLPWFSN
Length:280
Mass (Da):32,644
Last modified:October 1, 2000 - v1
Checksum:iB51959FE356C48E1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF216756 mRNA. Translation: AAF67863.1.
AB012248 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED95935.1.
RefSeqiNP_568727.1. NM_124419.4. [Q9M643-1]
UniGeneiAt.14737.

Genome annotation databases

EnsemblPlantsiAT5G50375.1; AT5G50375.1; AT5G50375. [Q9M643-1]
GeneIDi835105.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF216756 mRNA. Translation: AAF67863.1.
AB012248 Genomic DNA. No translation available.
CP002688 Genomic DNA. Translation: AED95935.1.
RefSeqiNP_568727.1. NM_124419.4. [Q9M643-1]
UniGeneiAt.14737.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi20351. 6 interactions.
STRINGi3702.AT5G50375.2.

PTM databases

iPTMnetiQ9M643.

Proteomic databases

PaxDbiQ9M643.
PRIDEiQ9M643.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G50375.1; AT5G50375.1; AT5G50375. [Q9M643-1]
GeneIDi835105.

Organism-specific databases

TAIRiAT5G50375.

Phylogenomic databases

eggNOGiENOG410IHJA. Eukaryota.
ENOG410YNGH. LUCA.
HOGENOMiHOG000243779.
InParanoidiQ9M643.
OMAiQSGLPWF.
PhylomeDBiQ9M643.

Enzyme and pathway databases

BioCyciARA:AT5G50375-MONOMER.
ARA:GQT-272-MONOMER.
MetaCyc:AT5G50375-MONOMER.
BRENDAi5.5.1.9. 399.

Miscellaneous databases

PROiQ9M643.

Gene expression databases

ExpressionAtlasiQ9M643. baseline and differential.
GenevisibleiQ9M643. AT.

Family and domain databases

InterProiIPR020532. Cycloeucalenol_cycloisomerase.
[Graphical view]
ProDomiPD317471. Cycloeucalenol_cycloisomerase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Functional cloning of an Arabidopsis thaliana cDNA encoding cycloeucalenol cycloisomerase."
    Lovato M.A., Hart E.A., Segura M.J.R., Giner J.-L., Matsuda S.P.T.
    J. Biol. Chem. 275:13394-13397(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence features of the regions of 1,367,185 bp covered by 19 physically assigned P1 and TAC clones."
    Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N., Tabata S.
    DNA Res. 5:203-216(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.

Entry informationi

Entry nameiCCI1_ARATH
AccessioniPrimary (citable) accession number: Q9M643
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: October 1, 2000
Last modified: May 11, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.