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Q9M5X6 (NLTP_PYRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Non-specific lipid-transfer protein

Short name=LTP
Alternative name(s):
Allergen=Pyr c 3
OrganismPyrus communis (Pear) (Pyrus domestica)
Taxonomic identifier23211 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsRosalesRosaceaeMaloideaeMaleaePyrus

Protein attributes

Sequence length115 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plant non-specific lipid-transfer proteins transfer phospholipids as well as galactolipids across membranes. May play a role in wax or cutin deposition in the cell walls of expanding epidermal cells and certain secretory tissues By similarity.

Allergenic properties

Causes an allergic reaction in human.

Sequence similarities

Belongs to the plant LTP family.

Ontologies

Keywords
   Biological processTransport
   DiseaseAllergen
   DomainSignal
   LigandLipid-binding
   PTMDisulfide bond
Gene Ontology (GO)
   Biological_processlipid transport

Inferred from electronic annotation. Source: InterPro

   Molecular_functionlipid binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2424 Potential
Chain25 – 11591Non-specific lipid-transfer protein
PRO_0000018404

Amino acid modifications

Disulfide bond27 ↔ 74 By similarity
Disulfide bond37 ↔ 51 By similarity
Disulfide bond52 ↔ 97 By similarity
Disulfide bond72 ↔ 111 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9M5X6 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 90543BD036AA8D65

FASTA11511,463
        10         20         30         40         50         60 
MASSAVIKLA LVVALCMAVS VAHAITCSQV SANLAPCINY VRSGGAVPPA CCNGIKTING 

        70         80         90        100        110 
LAKTTPDRQA ACNCLKNLAG SVSGVNPGNA ESLPGKCGVN VPYKISTSTN CATVK 

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References

[1]"Cloning of a cDNA encoding a lipid transfer protein as a potential allergen from Pyrus communis."
Scheurer S., Wangorsch A., Haustein D., Vieths S.
Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF221503 mRNA. Translation: AAF26451.1.

3D structure databases

ProteinModelPortalQ9M5X6.
SMRQ9M5X6. Positions 25-115.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome1066. Pyr c 3.
3458. Pyr c 3.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR016140. Bifunc_inhib/LTP/seed_store.
IPR000528. Plant_LTP.
[Graphical view]
PfamPF00234. Tryp_alpha_amyl. 1 hit.
[Graphical view]
PRINTSPR00382. LIPIDTRNSFER.
SMARTSM00499. AAI. 1 hit.
[Graphical view]
SUPFAMSSF47699. SSF47699. 1 hit.
PROSITEPS00597. PLANT_LTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNLTP_PYRCO
AccessionPrimary (citable) accession number: Q9M5X6
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2001
Last sequence update: October 1, 2000
Last modified: February 19, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Allergens

Nomenclature of allergens and list of entries