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Q9M5M0 (CHS7_PICMA) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase 7

EC=2.3.1.74
Alternative name(s):
Naregenin-chalcone synthase 7
Gene names
Name:CSF7
OrganismPicea mariana (Black spruce) (Abies mariana)
Taxonomic identifier3335 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaPinidaePinalesPinaceaePicea

Protein attributes

Sequence length395 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 395395Chalcone synthase 7
PRO_0000216040

Sites

Active site1691 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9M5M0 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 622A09497800ADED

FASTA39543,175
        10         20         30         40         50         60 
MAGGLMADLE AFRKAQRADG PATILAIGTA TPPNAVDQST YPDYYFKITN SEHMTELKEK 

        70         80         90        100        110        120 
FQRMCDKSAI KKRYMYLTDE ILKENPNVCE YMAPSLDARQ DMVVVEVPRL GKEAATKAIK 

       130        140        150        160        170        180 
EWGQPKSKIT HVIFCTTSGV DMPGADYQLT KLLGLRPSVK RVMMYQQGCF AGGTVLRVAK 

       190        200        210        220        230        240 
DLAENNRGAR VLVVCSEITA VTFRGPSDTH LDSMVGQALF GDGAAALIVG ADPIPQVEKP 

       250        260        270        280        290        300 
CFELMWTAQT ILPDSDGAID GHLREVGLTF HLLKDVPGLI SKNIEKSLVE AFQQFGISDW 

       310        320        330        340        350        360 
NQLFWIAHPG GPAILDQVEA KLNLDPKKLR ATRQVLSEYG NMSSACVHFI LDEMRKSSNE 

       370        380        390 
KGCSTTGEGL DVGVLFGFGP GLTVETVVLK SVPLQ 

« Hide

References

[1]"Characterization of the black spruce chalcone gene family."
Xue B.G., Rutledge R.G.
Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Cone.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF227627 mRNA. Translation: AAF35890.1.

3D structure databases

ProteinModelPortalQ9M5M0.
SMRQ9M5M0. Positions 13-394.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHS7_PICMA
AccessionPrimary (citable) accession number: Q9M5M0
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: March 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways