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Protein

Translationally-controlled tumor protein homolog

Gene

TCTP

Organism
Hordeum vulgare (Barley)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in calcium binding and microtubule stabilization.By similarity

Keywords - Ligandi

Calcium

Names & Taxonomyi

Protein namesi
Recommended name:
Translationally-controlled tumor protein homolog
Short name:
TCTP
Alternative name(s):
HTP
Gene namesi
Name:TCTP
OrganismiHordeum vulgare (Barley)
Taxonomic identifieri4513 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaeBOP cladePooideaeTriticodaeTriticeaeHordeinaeHordeum

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002113021 – 168Translationally-controlled tumor protein homologAdd BLAST168

Proteomic databases

PRIDEiQ9M5G3.

Interactioni

Protein-protein interaction databases

STRINGi4513.MLOC_77840.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M5G3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 168TCTPPROSITE-ProRule annotationAdd BLAST168

Sequence similaritiesi

Belongs to the TCTP family.PROSITE-ProRule annotation
Contains 1 TCTP domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M5G3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLVYQDKLSG DELLSDSFPY RELENGVLWE VDGHWVVQGA VDVDIGANPS
60 70 80 90 100
AEGGGEDEGV DDQAVKVVDI VDTFRLQEQP AFDKKQFIAY IKRYIKNLTA
110 120 130 140 150
KLEGEELDAF KKNVESATKY LLSKLKDLQF FVGESMHDDG SVVFAYYREG
160
AADPTFLYFA HGLKEVKC
Length:168
Mass (Da):18,884
Last modified:January 23, 2002 - v2
Checksum:i67E7D0375B2C4D1E
GO

Sequence cautioni

The sequence AAF61933 differs from that shown. Reason: Frameshift at position 145.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230786 mRNA. Translation: AAF61933.1. Frameshift.
UniGeneiHv.22789.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF230786 mRNA. Translation: AAF61933.1. Frameshift.
UniGeneiHv.22789.

3D structure databases

ProteinModelPortaliQ9M5G3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi4513.MLOC_77840.1.

Proteomic databases

PRIDEiQ9M5G3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1727. Eukaryota.
ENOG4111FVP. LUCA.

Family and domain databases

Gene3Di2.170.150.10. 1 hit.
InterProiIPR011057. Mss4-like.
IPR011323. Mss4/transl-control_tumor.
IPR018103. Translation_control_tumour_CS.
IPR018105. Translational_control_tumour_p.
[Graphical view]
PANTHERiPTHR11991. PTHR11991. 1 hit.
PfamiPF00838. TCTP. 1 hit.
[Graphical view]
PRINTSiPR01653. TCTPROTEIN.
SUPFAMiSSF51316. SSF51316. 1 hit.
PROSITEiPS01002. TCTP_1. 1 hit.
PS01003. TCTP_2. 1 hit.
PS51797. TCTP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTCTP_HORVU
AccessioniPrimary (citable) accession number: Q9M5G3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: January 23, 2002
Last modified: July 6, 2016
This is version 66 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.