Reviewed,
UniProtKB/Swiss-Prot Q9M591 (CRD1_ARATH)
Last modified
February 9, 2010.
Version 62.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase EC=1.14.13.81 Alternative name(s): Copper response defect 1 protein Dicarboxylate diiron protein Short name=AtZIP | ||||||||
| Gene names |
| ||||||||
| Organism | Arabidopsis thaliana (Mouse-ear cress) [Complete proteome] | ||||||||
| Taxonomic identifier | 3702 [NCBI] | ||||||||
| Taxonomic lineage | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Arabidopsis |
Protein attributes
| Sequence length | 409 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Function | Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME). Ref.6 |
| Catalytic activity | Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. Ref.6 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. Ref.6 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. Ref.6 |
| Cofactor | Iron By similarity. |
| Pathway | |
| Subcellular location | Plastid › chloroplast inner membrane; Peripheral membrane protein. Plastid › chloroplast thylakoid membrane; Peripheral membrane protein Ref.6. |
| Sequence similarities | Belongs to the acsF family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transit peptide | 1 – 36 | 36 | Chloroplast Potential | ||||||
| Chain | 37 – 409 | 373 | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic | PRO_0000000598 | |||||
Experimental info | |||||||||
| Sequence conflict | 14 | 1 | F → I Ref.1 | ||||||
| Sequence conflict | 157 | 1 | L → S in AAB18942. Ref.1 | ||||||
| Sequence conflict | 216 – 219 | 4 | TYLS → RAAR Ref.5 | ||||||
| Sequence conflict | 299 | 1 | C → W in AAF63476. Ref.2 | ||||||
| Sequence conflict | 310 – 312 | 3 | LNT → FKH Ref.5 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "PNZIP is a novel mesophyll-specific cDNA that is regulated by phytochrome and the circadian rhythm and encodes a protein with a leucine zipper motif." Zheng C.C., Porat R., Lu P., O'Neill S.D. Plant Physiol. 116:27-35(1998) [PubMed: 9449833] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [2] | "The Crd1 gene encodes a putative di-iron enzyme required for photosystem I accumulation in copper deficiency and hypoxia in Chlamydomonas reinhardtii." Moseley J.L., Quinn J., Eriksson M., Merchant S. EMBO J. 19:2139-2151(2000) [PubMed: 10811605] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
| [3] | "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana." Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. Tabata S.Nature 408:820-822(2000) [PubMed: 11130713] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia. |
| [4] | "Cloning and characteristics of AT103 gene promoter." Liu N., Zheng C. Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-76. |
| [5] | "Isolation of molecular markers for salt stress responses in Arabidopsis thaliana." Pih K.T., Jang H.J., Kang S.G., Piao H.L., Hwang I. Mol. Cells 7:567-571(1997) [PubMed: 9339905] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 215-313. Strain: cv. Columbia. |
| [6] | "Arabidopsis CHL27, located in both envelope and thylakoid membranes, is required for the synthesis of protochlorophyllide." Tottey S., Block M.A., Allen M., Westergren T., Albrieux C., Scheller H.V., Merchant S., Jensen P.E. Proc. Natl. Acad. Sci. U.S.A. 100:16119-16124(2003) [PubMed: 14673103] [Abstract] Cited for: FUNCTION, ENZYME ACTIVITY, SUBCELLULAR LOCATION. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U38232 mRNA. Translation: AAB18942.1. Different initiation. AF236101 mRNA. Translation: AAF63476.1. AL138655 Genomic DNA. Translation: CAB72164.1. AY170319 Genomic DNA. Translation: AAO11785.1. U75599 mRNA. Translation: AAB51703.1. |
| IPI | IPI00517126. |
| PIR | T47754. |
| RefSeq | NP_191253.1. |
| UniGene | At.48778 At.70999 Rra.4206 Rsa.6163 |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q9M591. |
Proteomic databases | |
| PRIDE | Q9M591. |
Genome annotation databases | |
| GeneID | 824861. |
| GenomeReviews | Gene locus AT3G56940 in contig BA000014_GR. |
| KEGG | ath:AT3G56940. |
| NMPDR | fig|3702.1.peg.17023. |
Organism-specific databases | |
| TAIR | At3g56940. |
Phylogenomic databases | |
| eggNOG | NOG10633. |
| HOGENOM | HBG284843. |
| InParanoid | Q9M591. |
| OMA | YARYITI. |
Enzyme and pathway databases | |
| BioCyc | MetaCyc:AT3G56940-MONOMER. |
| BRENDA | 1.14.13.81. 302. |
Gene expression databases | |
| Genevestigator | Q9M591. |
| GermOnline | AT3G56940. Arabidopsis thaliana. |
Family and domain databases | |
| InterPro | IPR008434. AcsF. IPR009078. Ferritin/RR-like. IPR003251. Rubrerythrin. [Graphical view] |
| Pfam | PF02915. Rubrerythrin. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR02029. AcsF. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | CRD1_ARATH | ||||||||
| Accession | Primary (citable) accession number: Q9M591 Secondary accession number(s): O04051 Q9M1K4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||
Relevant documents
| Arabidopsis thaliana Arabidopsis thaliana: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


