Q9M4X7 (EXPA6_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Expansin-A6

Alternative name(s):
Alpha-expansin-6
OsEXP6
OsEXPA6
OsaEXPa1.24

Gene names

Name:	EXPA6
Synonyms:	EXP6
Ordered Locus Names:	Os03g0336400, LOC_Os03g21820

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May cause loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found. May be required for rapid internodal elongation in deepwater rice during submergence By similarity.
Subcellular location	Secreted › cell wall By similarity. Membrane; Peripheral membrane protein By similarity.
Tissue specificity	Expressed in panicles and flowers. Ref.4
Developmental stage	Expressed in the growing regions of coleoptiles, internodes and leaves. Ref.1
Induction	By gibberellin (GA3) and wounding. Ref.1
Sequence similarities	Belongs to the expansin family. Expansin A subfamily. Contains 1 expansin-like CBD domain. Contains 1 expansin-like EG45 domain.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Cell wall Membrane Secreted
Domain	Signal
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	plant-type cell wall organization Inferred from electronic annotation. Source: InterPro
Cellular component	cell wall Inferred from electronic annotation. Source: UniProtKB-SubCell extracellular region Inferred from electronic annotation. Source: UniProtKB-KW membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 22	22	Potential
	Chain	23 – 259	237	Expansin-A6		PRO_0000251985
Regions
	Domain	46 – 161	116	Expansin-like EG45
	Domain	171 – 256	86	Expansin-like CBD
Amino acid modifications
	Disulfide bond	49 ↔ 77		By similarity
	Disulfide bond	80 ↔ 156		By similarity
	Disulfide bond	85 ↔ 93		By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9M4X7 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: 2420BE396261940C	FASTA	259	27,138
	10 20 30 40 50 60 MAPPLLLLLA SLLLVAARRA LGLGLGQWQP GHATFYGGGD ASGTMGGACG YGNLYSQGYG 70 80 90 100 110 120 TSTAALSTAL FNRGLSCGSC YELRCAGDHR RSCLPGGATV TVTATNFCPP NYALPSDGGG 130 140 150 160 170 180 WCNPPRRHFD LAEPAFLRIA RHAAGIVPVS FRRVACARKG GVRFTVNGHA YFNLVLVTNV 190 200 210 220 230 240 GGAGDVRSLA VKGSGSGSRV GGRWQPMSRN WGQNWQSNAY LDGKALSFRV TAGDGRSLTC 250 ADVAPAGWQF GQTFEGRQF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression of alpha-expansin and expansin-like genes in deepwater rice." Lee Y., Kende H. Plant Physiol. 130:1396-1405(2002) [PubMed: 12428004] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, INDUCTION.
[2]	"Sequence, annotation, and analysis of synteny between rice chromosome 3 and diverged grass species." The rice chromosome 3 sequencing consortium Buell C.R., Yuan Q., Ouyang S., Liu J., Zhu W., Wang A., Maiti R., Haas B., Wortman J., Pertea M., Jones K.M., Kim M., Overton L., Tsitrin T., Fadrosh D., Bera J., Weaver B., Jin S. , Johri S., Reardon M., Webb K., Hill J., Moffat K., Tallon L., Van Aken S., Lewis M., Utterback T., Feldblyum T., Zismann V., Iobst S., Hsiao J., de Vazeille A.R., Salzberg S.L., White O., Fraser C.M., Yu Y., Kim H., Rambo T., Currie J., Collura K., Kernodle-Thompson S., Wei F., Kudrna K., Ammiraju J.S.S., Luo M., Goicoechea J.L., Wing R.A., Henry D., Oates R., Palmer M., Pries G., Saski C., Simmons J., Soderlund C., Nelson W., de la Bastide M., Spiegel L., Nascimento L., Huang E., Preston R., Zutavern T., Palmer L., O'Shaughnessy A., Dike S., McCombie W.R., Minx P., Cordum H., Wilson R., Jin W., Lee H.R., Jiang J., Jackson S. Genome Res. 15:1284-1291(2005) [PubMed: 16109971] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
[3]	"Nomenclature for members of the expansin superfamily of genes and proteins." Kende H., Bradford K.J., Brummell D.A., Cho H.-T., Cosgrove D.J., Fleming A.J., Gehring C., Lee Y., McQueen-Mason S.J., Rose J.K.C., Voesenek L.A.C. Plant Mol. Biol. 55:311-314(2004) [PubMed: 15604683] [Abstract] Cited for: NOMENCLATURE.
[4]	"Characterization and transcriptional expression of the alpha-expansin gene family in rice." Shin J.-H., Jeong D.-H., Park M.C., An G. Mol. Cells 20:210-218(2005) [PubMed: 16267395] [Abstract] Cited for: TISSUE SPECIFICITY.

Web resources

EXPANSIN homepage

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF247163 mRNA. Translation: AAF62181.1. DP000009 Genomic DNA. Translation: ABF95820.1.
RefSeq	NP_001050041.1. NM_001056576.1.
UniGene	Os.2367.
3D structure databases
HSSP	HSSP built from PDB template 1N10 based on UniProtKB P43213.
ProteinModelPortal	Q9M4X7.
ModBase	Search...
Proteomic databases
PRIDE	Q9M4X7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os03g21820.1; LOC_Os03g21820.1; LOC_Os03g21820.
GeneID	4332763.
KEGG	osa:4332763.
Organism-specific databases
Gramene	Q9M4X7.
Phylogenomic databases
GeneTree	EPGT00070000027927.
OMA	EIRCEND.
PhylomeDB	Q9M4X7.
Family and domain databases
InterPro	IPR014733. Barwin-like_endoglucanase. IPR009009. Barwin-related_endoglucanase. IPR007118. Expan_Lol_pI. IPR007117. Expan_Lol_pI_C. IPR002963. Expansin. IPR007112. Expansin/allergen_DPBB_dom. [Graphical view]
Gene3D	G3DSA:2.40.40.10. Barwin. 1 hit. G3DSA:2.60.40.760. Expan_Lol_pI_C. 1 hit.
Pfam	PF03330. DPBB_1. 1 hit. PF01357. Pollen_allerg_1. 1 hit. [Graphical view]
PRINTS	PR01226. EXPANSIN. PR01225. EXPANSNFAMLY.
SMART	SM00837. DPBB_1. 1 hit. [Graphical view]
SUPFAM	SSF50685. Barwin_like. 1 hit. SSF49590. Expan_Lol_pI_C. 1 hit.
PROSITE	PS50843. EXPANSIN_CBD. 1 hit. PS50842. EXPANSIN_EG45. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EXPA6_ORYSJ

Accession

Primary (citable) accession number: Q9M4X7
Secondary accession number(s): Q10LS8

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 3, 2006
Last sequence update:	October 1, 2000
Last modified:	December 14, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program