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Q9M4T8

- PSA5_SOYBN

UniProt

Q9M4T8 - PSA5_SOYBN

Protein

Proteasome subunit alpha type-5

Gene

PAE1

Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

    Catalytic activityi

    Cleavage of peptide bonds with very broad specificity.PROSITE-ProRule annotation

    GO - Molecular functioni

    1. ribonuclease activity Source: EnsemblPlants/Gramene
    2. threonine-type endopeptidase activity Source: UniProtKB-KW

    GO - Biological processi

    1. response to cadmium ion Source: EnsemblPlants/Gramene
    2. ubiquitin-dependent protein catabolic process Source: InterPro

    Keywords - Molecular functioni

    Hydrolase, Protease, Threonine protease

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Proteasome subunit alpha type-5 (EC:3.4.25.1)
    Alternative name(s):
    20S proteasome alpha subunit E
    20S proteasome subunit alpha-5
    Gene namesi
    Name:PAE1
    OrganismiGlycine max (Soybean) (Glycine hispida)
    Taxonomic identifieri3847 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
    ProteomesiUP000008827: Unplaced

    Subcellular locationi

    Cytoplasm By similarity. Nucleus By similarity

    GO - Cellular componenti

    1. cytosolic ribosome Source: EnsemblPlants/Gramene
    2. nucleus Source: UniProtKB-SubCell
    3. plasma membrane Source: EnsemblPlants/Gramene
    4. proteasome core complex, alpha-subunit complex Source: InterPro
    5. vacuolar membrane Source: EnsemblPlants/Gramene

    Keywords - Cellular componenti

    Cytoplasm, Nucleus, Proteasome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 237237Proteasome subunit alpha type-5PRO_0000124127Add
    BLAST

    Proteomic databases

    PRIDEiQ9M4T8.
    ProMEXiQ9M4T8.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9M4T8.

    Interactioni

    Subunit structurei

    The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9M4T8.
    SMRiQ9M4T8. Positions 8-234.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the peptidase T1A family.PROSITE-ProRule annotation

    Phylogenomic databases

    KOiK02729.

    Family and domain databases

    Gene3Di3.60.20.10. 1 hit.
    InterProiIPR029055. Ntn_hydrolases_N.
    IPR000426. Proteasome_asu_N.
    IPR023332. Proteasome_suA-type.
    IPR001353. Proteasome_sua/b.
    [Graphical view]
    PfamiPF00227. Proteasome. 1 hit.
    PF10584. Proteasome_A_N. 1 hit.
    [Graphical view]
    SMARTiSM00948. Proteasome_A_N. 1 hit.
    [Graphical view]
    SUPFAMiSSF56235. SSF56235. 1 hit.
    PROSITEiPS00388. PROTEASOME_ALPHA_1. 1 hit.
    PS51475. PROTEASOME_ALPHA_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9M4T8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFLTRTEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGL KTKEGVVLAV    50
    EKRITSPLLE PSSVEKIMEI DEHIGCAMSG LIADARTLVE HARVETQNHR 100
    FSYGEPMTVE STTQALCDLA LRFGEGDEES MSRPFGVSLL IAGHDENGPS 150
    LYYTDPSGTF WQCNGKAIGS GSEGADSSLQ EQFNKDLTLQ EAETIALSIL 200
    KQVMEEKVTP NNVDIAKVAP TYHLYTPSEV EAVISRL 237
    Length:237
    Mass (Da):25,980
    Last modified:October 1, 2000 - v1
    Checksum:iADEB685608400F67
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF255338 mRNA. Translation: AAF70292.1.
    RefSeqiNP_001235159.1. NM_001248230.1.
    UniGeneiGma.55189.

    Genome annotation databases

    GeneIDi547598.
    KEGGigmx:547598.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF255338 mRNA. Translation: AAF70292.1 .
    RefSeqi NP_001235159.1. NM_001248230.1.
    UniGenei Gma.55189.

    3D structure databases

    ProteinModelPortali Q9M4T8.
    SMRi Q9M4T8. Positions 8-234.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9M4T8.
    ProMEXi Q9M4T8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 547598.
    KEGGi gmx:547598.

    Phylogenomic databases

    KOi K02729.

    Gene expression databases

    Genevestigatori Q9M4T8.

    Family and domain databases

    Gene3Di 3.60.20.10. 1 hit.
    InterProi IPR029055. Ntn_hydrolases_N.
    IPR000426. Proteasome_asu_N.
    IPR023332. Proteasome_suA-type.
    IPR001353. Proteasome_sua/b.
    [Graphical view ]
    Pfami PF00227. Proteasome. 1 hit.
    PF10584. Proteasome_A_N. 1 hit.
    [Graphical view ]
    SMARTi SM00948. Proteasome_A_N. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56235. SSF56235. 1 hit.
    PROSITEi PS00388. PROTEASOME_ALPHA_1. 1 hit.
    PS51475. PROTEASOME_ALPHA_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of a cDNA encoding 20S proteasome subunit from soybean."
      Choi J., Bhoo S.H., Park P.B.
      Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPSA5_SOYBN
    AccessioniPrimary (citable) accession number: Q9M4T8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 8, 2000
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Peptidase families
      Classification of peptidase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3