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Q9M4T8 (PSA5_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Proteasome subunit alpha type-5

EC=3.4.25.1
Alternative name(s):
20S proteasome alpha subunit E
20S proteasome subunit alpha-5
Gene names
Name:PAE1
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.

Catalytic activity

Cleavage of peptide bonds with very broad specificity.

Subunit structure

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits. The 20S proteasome core is composed of 28 subunits that are arranged in four stacked rings, resulting in a barrel-shaped structure. The two end rings are each formed by seven alpha subunits, and the two central rings are each formed by seven beta subunits. The catalytic chamber with the active sites is on the inside of the barrel By similarity.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the peptidase T1A family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Proteasome subunit alpha type-5
PRO_0000124127

Sequences

Sequence LengthMass (Da)Tools
Q9M4T8 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: ADEB685608400F67

FASTA23725,980
        10         20         30         40         50         60 
MFLTRTEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGL KTKEGVVLAV EKRITSPLLE 

        70         80         90        100        110        120 
PSSVEKIMEI DEHIGCAMSG LIADARTLVE HARVETQNHR FSYGEPMTVE STTQALCDLA 

       130        140        150        160        170        180 
LRFGEGDEES MSRPFGVSLL IAGHDENGPS LYYTDPSGTF WQCNGKAIGS GSEGADSSLQ 

       190        200        210        220        230 
EQFNKDLTLQ EAETIALSIL KQVMEEKVTP NNVDIAKVAP TYHLYTPSEV EAVISRL 

« Hide

References

[1]"Isolation of a cDNA encoding 20S proteasome subunit from soybean."
Choi J., Bhoo S.H., Park P.B.
Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF255338 mRNA. Translation: AAF70292.1.
RefSeqNP_001235159.1. NM_001248230.1.
UniGeneGma.55189.

3D structure databases

ProteinModelPortalQ9M4T8.
SMRQ9M4T8. Positions 8-234.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ9M4T8.
ProMEXQ9M4T8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID547598.
KEGGgmx:547598.

Phylogenomic databases

KOK02729.

Gene expression databases

GenevestigatorQ9M4T8.

Family and domain databases

Gene3D3.60.20.10. 1 hit.
InterProIPR029055. Ntn_hydrolases_N.
IPR000426. Proteasome_asu_N.
IPR023332. Proteasome_suA-type.
IPR001353. Proteasome_sua/b.
[Graphical view]
PfamPF00227. Proteasome. 1 hit.
PF10584. Proteasome_A_N. 1 hit.
[Graphical view]
SMARTSM00948. Proteasome_A_N. 1 hit.
[Graphical view]
SUPFAMSSF56235. SSF56235. 1 hit.
PROSITEPS00388. PROTEASOME_ALPHA_1. 1 hit.
PS51475. PROTEASOME_ALPHA_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePSA5_SOYBN
AccessionPrimary (citable) accession number: Q9M4T8
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: October 1, 2000
Last modified: June 11, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Peptidase families

Classification of peptidase families and list of entries