Reviewed, UniProtKB/Swiss-Prot Q9M4G4 (PGMC_SOLTU)

Names and origin

Protein names

Recommended name:
    Phosphoglucomutase, cytoplasmic
      Short name=PGM
    EC=5.4.2.2
Alternative name(s):
    Glucose phosphomutase

Gene names

Name:	PGM1
Synonyms:	PGM I

Organism

Solanum tuberosum (Potato)

Taxonomic identifier

4113 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › asterids › lamiids › Solanales › Solanaceae › Solanoideae › Solaneae › Solanum

Protein attributes

Sequence length	583 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	This enzyme participates in both the breakdown and synthesis of glucose By similarity.
Catalytic activity	Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glucose metabolism
Cellular component	Cytoplasm
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Gene Ontology (GO)
Biological process	glucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucomutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 583	583	Phosphoglucomutase, cytoplasmic		PRO_0000147806
Sites
	Active site	124	1	Phosphoserine intermediate By similarity
	Metal binding	124	1	Magnesium; via phosphate group By similarity
	Metal binding	300	1	Magnesium By similarity
	Metal binding	302	1	Magnesium By similarity
	Metal binding	304	1	Magnesium By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9M4G4-1 [UniParc]. Last modified October 1, 2000. Version 1. Checksum: DF3E24B9972C7CCA	FASTA	583	63,470
	10 20 30 40 50 60 MANFKVSRVE TTPFEGQKPG TSGLRKKVKV FIQPHYLQNF VQATFNALGA DRVEGATLVV 70 80 90 100 110 120 SGDGRYYSKD AIQIITKMAA ANGVRRVWIG QNGLLSTPAV SAVVRERVGA DGSKATGAFI 130 140 150 160 170 180 LTASHNPGGP HEDFGIKYNM ENGGPAPEGI TNKIYENTTT IKEYLIAEGL PDVDISTTGV 190 200 210 220 230 240 SSFEGPKGKF DVDVFDSTSD YLKLLKSIFD FPAIQKLLSS PKFSFCYDAL HGVAGVHAKR 250 260 270 280 290 300 IFVEELGANE SSLVNCVPKE DFGGGHPDPN LTYAKELVAR MGLSKTHSEP NPPEFGAAAD 310 320 330 340 350 360 GDGDRNMVLG KRFFVTPSDS VAIIAANAVQ AIPYFSGGLK GVARSMPTSA ALDIVAKHLN 370 380 390 400 410 420 LKFFEVPTGW KFFGNLMDAG MCSICGEESF GTGSDHIREK DGIWAVLAWL SILAYKNKDN 430 440 450 460 470 480 LGEGNLVSVE DIVRQHWAIY GRHYYTRYDY ENVNADGAKD LMAHLVKLQS SIDEVNKLIK 490 500 510 520 530 540 GIRSDVSNVV HADEFEYKDP VDGSVSKHQG IRYLFEDGSR LVFRLSGTGS EGATIRLYIE 550 560 570 580 QYEKDSSKIG RDSQEALAPL VEVALKLSKM QEYTSRSAPT VIT

References

[1]	Tauberger E. Thesis (1999), Freie Universitaet Berlin, Germany Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Tuber.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AJ240054 mRNA. Translation: CAB93681.1.
3D structure databases
HSSP	HSSP built from PDB template 3PMG based on UniProtKB P00949.
ModBase	Search...
Enzyme and pathway databases
BRENDA	5.4.2.2. 296.
Family and domain databases
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PGMC_SOLTU

Accession

Primary (citable) accession number: Q9M4G4

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 24, 2001
Last sequence update:	October 1, 2000
Last modified:	June 16, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)