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Protein

Protein NRT1/ PTR FAMILY 8.1

Gene

NPF8.1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Peptide transporter. Mediates the transport of di- and tripeptides. High affinity transporter with low selectivity. No transport of amino acids.2 Publications

GO - Molecular functioni

  • dipeptide transporter activity Source: TAIR
  • tripeptide transporter activity Source: TAIR

GO - Biological processi

  • dipeptide transport Source: TAIR
  • nitrogen compound metabolic process Source: TAIR
  • protein transport Source: UniProtKB-KW
  • tripeptide transport Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Enzyme and pathway databases

BRENDAi3.6.3.43. 399.

Protein family/group databases

TCDBi2.A.17.3.7. the proton-dependent oligopeptide transporter (pot/ptr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NRT1/ PTR FAMILY 8.1
Short name:
AtNPF8.1
Alternative name(s):
Peptide transporter PTR1
Gene namesi
Name:NPF8.1
Synonyms:PTR1
Ordered Locus Names:At3g54140
ORF Names:F24B22.100
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G54140.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei99 – 119HelicalSequence analysisAdd BLAST21
Transmembranei140 – 160HelicalSequence analysisAdd BLAST21
Transmembranei182 – 202HelicalSequence analysisAdd BLAST21
Transmembranei210 – 230HelicalSequence analysisAdd BLAST21
Transmembranei329 – 349HelicalSequence analysisAdd BLAST21
Transmembranei377 – 397HelicalSequence analysisAdd BLAST21
Transmembranei414 – 434HelicalSequence analysisAdd BLAST21
Transmembranei454 – 474HelicalSequence analysisAdd BLAST21
Transmembranei494 – 514HelicalSequence analysisAdd BLAST21
Transmembranei537 – 557HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: TAIR
  • plasmodesma Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Disruption phenotypei

Reduced growth and lower N content when cultivated on dipeptides. No effect on germination.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003783221 – 570Protein NRT1/ PTR FAMILY 8.1Add BLAST570

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei98PhosphothreonineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9M390.
PRIDEiQ9M390.

Expressioni

Tissue specificityi

Expressed in cotyledons, hypocotyls, leaves, roots, flowers, pistils and vascular tissue of sepals, anthers, carpels and funiculi. Not detected in seeds.2 Publications

Gene expression databases

GenevisibleiQ9M390. AT.

Interactioni

Protein-protein interaction databases

BioGridi9898. 28 interactors.
STRINGi3702.AT3G54140.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M390.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1237. Eukaryota.
COG3104. LUCA.
HOGENOMiHOG000237400.
InParanoidiQ9M390.
OMAiMWGRYTT.
OrthoDBiEOG093606MH.
PhylomeDBiQ9M390.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 1 hit.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M390-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEKDVYTQD GTVDIHKNPA NKEKTGNWKA CRFILGNECC ERLAYYGMGT
60 70 80 90 100
NLVNYLESRL NQGNATAANN VTNWSGTCYI TPLIGAFIAD AYLGRYWTIA
110 120 130 140 150
TFVFIYVSGM TLLTLSASVP GLKPGNCNAD TCHPNSSQTA VFFVALYMIA
160 170 180 190 200
LGTGGIKPCV SSFGADQFDE NDENEKIKKS SFFNWFYFSI NVGALIAATV
210 220 230 240 250
LVWIQMNVGW GWGFGVPTVA MVIAVCFFFF GSRFYRLQRP GGSPLTRIFQ
260 270 280 290 300
VIVAAFRKIS VKVPEDKSLL FETADDESNI KGSRKLVHTD NLKFFDKAAV
310 320 330 340 350
ESQSDSIKDG EVNPWRLCSV TQVEELKSII TLLPVWATGI VFATVYSQMS
360 370 380 390 400
TMFVLQGNTM DQHMGKNFEI PSASLSLFDT VSVLFWTPVY DQFIIPLARK
410 420 430 440 450
FTRNERGFTQ LQRMGIGLVV SIFAMITAGV LEVVRLDYVK THNAYDQKQI
460 470 480 490 500
HMSIFWQIPQ YLLIGCAEVF TFIGQLEFFY DQAPDAMRSL CSALSLTTVA
510 520 530 540 550
LGNYLSTVLV TVVMKITKKN GKPGWIPDNL NRGHLDYFFY LLATLSFLNF
560 570
LVYLWISKRY KYKKAVGRAH
Length:570
Mass (Da):64,034
Last modified:October 1, 2000 - v1
Checksum:i7366F068DD97B3ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132957 Genomic DNA. Translation: CAB70988.1.
CP002686 Genomic DNA. Translation: AEE79192.1.
AF360155 mRNA. Translation: AAK25865.1.
AY113884 mRNA. Translation: AAM44932.1.
AY084773 mRNA. Translation: AAM61341.1.
PIRiT47573.
RefSeqiNP_190982.1. NM_115274.3.
UniGeneiAt.927.

Genome annotation databases

EnsemblPlantsiAT3G54140.1; AT3G54140.1; AT3G54140.
GeneIDi824581.
GrameneiAT3G54140.1; AT3G54140.1; AT3G54140.
KEGGiath:AT3G54140.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132957 Genomic DNA. Translation: CAB70988.1.
CP002686 Genomic DNA. Translation: AEE79192.1.
AF360155 mRNA. Translation: AAK25865.1.
AY113884 mRNA. Translation: AAM44932.1.
AY084773 mRNA. Translation: AAM61341.1.
PIRiT47573.
RefSeqiNP_190982.1. NM_115274.3.
UniGeneiAt.927.

3D structure databases

ProteinModelPortaliQ9M390.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi9898. 28 interactors.
STRINGi3702.AT3G54140.1.

Protein family/group databases

TCDBi2.A.17.3.7. the proton-dependent oligopeptide transporter (pot/ptr) family.

Proteomic databases

PaxDbiQ9M390.
PRIDEiQ9M390.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G54140.1; AT3G54140.1; AT3G54140.
GeneIDi824581.
GrameneiAT3G54140.1; AT3G54140.1; AT3G54140.
KEGGiath:AT3G54140.

Organism-specific databases

TAIRiAT3G54140.

Phylogenomic databases

eggNOGiKOG1237. Eukaryota.
COG3104. LUCA.
HOGENOMiHOG000237400.
InParanoidiQ9M390.
OMAiMWGRYTT.
OrthoDBiEOG093606MH.
PhylomeDBiQ9M390.

Enzyme and pathway databases

BRENDAi3.6.3.43. 399.

Miscellaneous databases

PROiQ9M390.

Gene expression databases

GenevisibleiQ9M390. AT.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR020846. MFS_dom.
IPR000109. POT_fam.
IPR018456. PTR2_symporter_CS.
[Graphical view]
PANTHERiPTHR11654. PTHR11654. 1 hit.
PfamiPF00854. PTR2. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 2 hits.
PROSITEiPS01022. PTR2_1. 1 hit.
PS01023. PTR2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiPTR1_ARATH
AccessioniPrimary (citable) accession number: Q9M390
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 16, 2009
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.