Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Vesicle-associated membrane protein 727

Gene

VAMP727

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in the targeting and/or fusion of transport vesicles to their target membrane.By similarity

GO - Molecular functioni

GO - Biological processi

  • exocytosis Source: GO_Central
  • protein targeting to vacuole Source: TAIR
  • vacuole organization Source: TAIR
  • vesicle fusion Source: GO_Central
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-associated membrane protein 727
Short name:
AtVAMP727
Gene namesi
Name:VAMP727
Ordered Locus Names:At3g54300
ORF Names:F24B22.260
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G54300.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 215215CytoplasmicSequence analysisAdd
BLAST
Transmembranei216 – 23621Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini237 – 2404VesicularSequence analysis

GO - Cellular componenti

  • early endosome membrane Source: UniProtKB-SubCell
  • endosome Source: TAIR
  • integral component of membrane Source: UniProtKB-KW
  • SNARE complex Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Endosome, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 240240Vesicle-associated membrane protein 727PRO_0000206760Add
BLAST

Proteomic databases

PaxDbiQ9M376.
PRIDEiQ9M376.

PTM databases

iPTMnetiQ9M376.

Expressioni

Tissue specificityi

Highly expressed in flowers. Detected in leaves, stems and roots.1 Publication

Gene expression databases

GenevisibleiQ9M376. AT.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi9914. 3 interactions.
STRINGi3702.AT3G54300.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M376.
SMRiQ9M376. Positions 5-207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini6 – 133128LonginPROSITE-ProRule annotationAdd
BLAST
Domaini149 – 20961v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated
Contains 1 longin domain.PROSITE-ProRule annotation
Contains 1 v-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9M376.
KOiK08511.
OMAiIACGGFK.
OrthoDBiEOG09360NHL.
PhylomeDBiQ9M376.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M376-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQKGLIYSF VAKGTVVLAE HTPYSGNFST IAVQCLQKLP TNSSKYTYSC
60 70 80 90 100
DGHTFNFLVD NGFVFLVVAD ESTGRSVPFV FLERVKEDFK KRYEASIKND
110 120 130 140 150
ERHPLADEDE DDDLFGDRFS VAYNLDREFG PILKEHMQYC MSHPEEMSKL
160 170 180 190 200
SKLKAQITEV KGIMMDNIEK VLDRGEKIEL LVDKTENLQF QADSFQRQGR
210 220 230 240
QLRRKMWLQS LQMKLMVAGA VFSFILIVWV VACGGFKCSS
Length:240
Mass (Da):27,460
Last modified:October 1, 2000 - v1
Checksum:i4805B9406E95D47B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132957 Genomic DNA. Translation: CAB71004.1.
CP002686 Genomic DNA. Translation: AEE79210.1.
CP002686 Genomic DNA. Translation: AEE79211.1.
BT011606 mRNA. Translation: AAS47612.1.
BT012242 mRNA. Translation: AAS76729.1.
AK229117 mRNA. Translation: BAF00993.1.
PIRiT47589.
RefSeqiNP_001078283.1. NM_001084814.2.
NP_190998.1. NM_115290.4.
UniGeneiAt.35121.

Genome annotation databases

EnsemblPlantsiAT3G54300.1; AT3G54300.1; AT3G54300.
AT3G54300.2; AT3G54300.2; AT3G54300.
GeneIDi824597.
GrameneiAT3G54300.1; AT3G54300.1; AT3G54300.
AT3G54300.2; AT3G54300.2; AT3G54300.
KEGGiath:AT3G54300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132957 Genomic DNA. Translation: CAB71004.1.
CP002686 Genomic DNA. Translation: AEE79210.1.
CP002686 Genomic DNA. Translation: AEE79211.1.
BT011606 mRNA. Translation: AAS47612.1.
BT012242 mRNA. Translation: AAS76729.1.
AK229117 mRNA. Translation: BAF00993.1.
PIRiT47589.
RefSeqiNP_001078283.1. NM_001084814.2.
NP_190998.1. NM_115290.4.
UniGeneiAt.35121.

3D structure databases

ProteinModelPortaliQ9M376.
SMRiQ9M376. Positions 5-207.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi9914. 3 interactions.
STRINGi3702.AT3G54300.1.

PTM databases

iPTMnetiQ9M376.

Proteomic databases

PaxDbiQ9M376.
PRIDEiQ9M376.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G54300.1; AT3G54300.1; AT3G54300.
AT3G54300.2; AT3G54300.2; AT3G54300.
GeneIDi824597.
GrameneiAT3G54300.1; AT3G54300.1; AT3G54300.
AT3G54300.2; AT3G54300.2; AT3G54300.
KEGGiath:AT3G54300.

Organism-specific databases

TAIRiAT3G54300.

Phylogenomic databases

eggNOGiKOG0859. Eukaryota.
COG5143. LUCA.
HOGENOMiHOG000042712.
InParanoidiQ9M376.
KOiK08511.
OMAiIACGGFK.
OrthoDBiEOG09360NHL.
PhylomeDBiQ9M376.

Miscellaneous databases

PROiQ9M376.

Gene expression databases

GenevisibleiQ9M376. AT.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
3.30.450.50. 1 hit.
InterProiIPR011012. Longin-like_dom.
IPR010908. Longin_dom.
IPR001388. Synaptobrevin.
[Graphical view]
PfamiPF13774. Longin. 1 hit.
PF00957. Synaptobrevin. 1 hit.
[Graphical view]
PRINTSiPR00219. SYNAPTOBREVN.
SMARTiSM01270. Longin. 1 hit.
[Graphical view]
SUPFAMiSSF64356. SSF64356. 1 hit.
PROSITEiPS50859. LONGIN. 1 hit.
PS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiVA727_ARATH
AccessioniPrimary (citable) accession number: Q9M376
Secondary accession number(s): Q53XE0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 106 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.