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Protein

F-box/kelch-repeat protein At3g61590

Gene

At3g61590

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins.By similarity

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

  • animal organ development Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143.

Names & Taxonomyi

Protein namesi
Recommended name:
F-box/kelch-repeat protein At3g61590
Gene namesi
Ordered Locus Names:At3g61590
ORF Names:F2A19.190
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G61590.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 411411F-box/kelch-repeat protein At3g61590PRO_0000283237Add
BLAST

Proteomic databases

PaxDbiQ9M310.
PRIDEiQ9M310.

Expressioni

Gene expression databases

GenevisibleiQ9M310. AT.

Interactioni

Subunit structurei

Part of a SCF (ASK-cullin-F-box) protein ligase complex (By similarity). Interacts with SKP1A/ASK1, SKP1B/ASK2, ASK3, ASK9, ASK11, ASK12, ASK13, ASK14, ASK16 and ASK18.By similarity1 Publication

Protein-protein interaction databases

BioGridi10646. 11 interactions.
IntActiQ9M310. 14 interactions.
STRINGi3702.AT3G61590.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M310.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini37 – 8347F-boxPROSITE-ProRule annotationAdd
BLAST
Repeati81 – 13555Kelch 1Add
BLAST
Repeati137 – 17842Kelch 2Add
BLAST
Repeati196 – 24651Kelch 3Add
BLAST
Repeati251 – 29949Kelch 4Add
BLAST
Repeati302 – 35049Kelch 5Add
BLAST
Repeati352 – 40150Kelch 6Add
BLAST

Domaini

The F-box is necessary for the interaction with ASK proteins.By similarity

Sequence similaritiesi

Contains 1 F-box domain.PROSITE-ProRule annotation
Contains 6 Kelch repeats.Curated

Keywords - Domaini

Kelch repeat, Repeat

Phylogenomic databases

eggNOGiENOG410IVAB. Eukaryota.
ENOG410XPZA. LUCA.
HOGENOMiHOG000238968.
InParanoidiQ9M310.
OMAiCGRLVNL.
OrthoDBiEOG09360AXW.
PhylomeDBiQ9M310.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR001810. F-box_dom.
IPR015915. Kelch-typ_b-propeller.
[Graphical view]
PfamiPF00646. F-box. 1 hit.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
[Graphical view]
SUPFAMiSSF81383. SSF81383. 1 hit.
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9M310-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEAETSWTNY PYSYITYVPE AESYREQSDD EAKVETFSMD SLLPDDLLER
60 70 80 90 100
ILSFLPIASI FRAGTVCKRW NEIVSSRRFL CNFSNNSVSQ RPWYFMFTTT
110 120 130 140 150
DDPSGYAYDP IIRKWYSFDL PCIETSNWFV ASSCGLVCFM DNDCRNKIYV
160 170 180 190 200
SNPITKQWRT LIEPPGHKST DYTAMSTSVN RANQAVNRAN RSYSVSIVKS
210 220 230 240 250
KQVPGNFFQW DLSIHLYSSE TMTWTTLVND VLSGWRGGNE SVICNNVLYF
260 270 280 290 300
MIYSTGGSDH RHGLIASNLS SIGSPSSGIL MRSFIPMPCS LTCGRLMNLR
310 320 330 340 350
ERLVIVGGIG KHDRPEVIKG IGIWVLKGKE WVEMAKMPQR FFQGFGEFDE
360 370 380 390 400
VFASSGTDDL VYIQSYGSPA LLTFDMNLKY WRWSQKCPVT KKFPLQLFTG
410
FCFEPRLEIA P
Length:411
Mass (Da):46,972
Last modified:October 1, 2000 - v1
Checksum:i0F2FEF44CA68ED00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132962 Genomic DNA. Translation: CAB71089.1.
CP002686 Genomic DNA. Translation: AEE80227.1.
CP002686 Genomic DNA. Translation: AEE80228.1.
AF386994 mRNA. Translation: AAK62439.1.
BT000054 mRNA. Translation: AAN15373.1.
PIRiT47951.
RefSeqiNP_001190155.1. NM_001203226.1.
NP_191718.1. NM_116024.2.
UniGeneiAt.951.

Genome annotation databases

EnsemblPlantsiAT3G61590.1; AT3G61590.1; AT3G61590.
AT3G61590.2; AT3G61590.2; AT3G61590.
GeneIDi825332.
GrameneiAT3G61590.1; AT3G61590.1; AT3G61590.
AT3G61590.2; AT3G61590.2; AT3G61590.
KEGGiath:AT3G61590.

Cross-referencesi

Web resourcesi

PlantsUBQ

A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL132962 Genomic DNA. Translation: CAB71089.1.
CP002686 Genomic DNA. Translation: AEE80227.1.
CP002686 Genomic DNA. Translation: AEE80228.1.
AF386994 mRNA. Translation: AAK62439.1.
BT000054 mRNA. Translation: AAN15373.1.
PIRiT47951.
RefSeqiNP_001190155.1. NM_001203226.1.
NP_191718.1. NM_116024.2.
UniGeneiAt.951.

3D structure databases

ProteinModelPortaliQ9M310.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi10646. 11 interactions.
IntActiQ9M310. 14 interactions.
STRINGi3702.AT3G61590.1.

Proteomic databases

PaxDbiQ9M310.
PRIDEiQ9M310.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G61590.1; AT3G61590.1; AT3G61590.
AT3G61590.2; AT3G61590.2; AT3G61590.
GeneIDi825332.
GrameneiAT3G61590.1; AT3G61590.1; AT3G61590.
AT3G61590.2; AT3G61590.2; AT3G61590.
KEGGiath:AT3G61590.

Organism-specific databases

TAIRiAT3G61590.

Phylogenomic databases

eggNOGiENOG410IVAB. Eukaryota.
ENOG410XPZA. LUCA.
HOGENOMiHOG000238968.
InParanoidiQ9M310.
OMAiCGRLVNL.
OrthoDBiEOG09360AXW.
PhylomeDBiQ9M310.

Enzyme and pathway databases

UniPathwayiUPA00143.

Miscellaneous databases

PROiQ9M310.

Gene expression databases

GenevisibleiQ9M310. AT.

Family and domain databases

Gene3Di2.120.10.80. 1 hit.
InterProiIPR001810. F-box_dom.
IPR015915. Kelch-typ_b-propeller.
[Graphical view]
PfamiPF00646. F-box. 1 hit.
[Graphical view]
SMARTiSM00256. FBOX. 1 hit.
[Graphical view]
SUPFAMiSSF81383. SSF81383. 1 hit.
PROSITEiPS50181. FBOX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiFBK77_ARATH
AccessioniPrimary (citable) accession number: Q9M310
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 3, 2007
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.