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Protein

Fatty-acid-binding protein 1

Gene

FAP1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Fatty-acid-binding protein. Interacts preferentially with saturated fatty acid. May be involved in alpha-linolenic (C18:3) metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei103Fatty acid1
Binding sitei116Fatty acid1
Binding sitei183Fatty acid1

GO - Molecular functioni

  • fatty acid binding Source: TAIR
  • intramolecular lyase activity Source: InterPro

GO - Biological processi

  • fatty acid metabolic process Source: TAIR

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty-acid-binding protein 1
Short name:
AtFAP1
Alternative name(s):
Chalcone-flavanone isomerase family protein 1
Gene namesi
Name:FAP1
Ordered Locus Names:At3g63170
ORF Names:F16M2.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

AraportiAT3G63170
TAIRilocus:2077229 AT3G63170

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chloroplast, Plastid

Pathology & Biotechi

Disruption phenotypei

No visible phenotype during vegetative growth, but shorter siliques containing a reduced number of viable seeds. Elevated total fatty-acid levels in leaves and seeds of plants grown at 15 and 22 degrees Celsius.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004220771 – 279Fatty-acid-binding protein 1Add BLAST279

Proteomic databases

PaxDbiQ9M1X2
PRIDEiQ9M1X2

PTM databases

iPTMnetiQ9M1X2

Expressioni

Tissue specificityi

Expressed in developing cotyledons, young seedlings, roots, seeds, embryos, macrospores, preanthesis and tapetum. Restricted to developing and reproductive tissues.1 Publication

Gene expression databases

ExpressionAtlasiQ9M1X2 baseline and differential
GenevisibleiQ9M1X2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G63170.1

Structurei

Secondary structure

1279
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni81 – 83Combined sources3
Beta strandi89 – 91Combined sources3
Turni92 – 94Combined sources3
Beta strandi95 – 106Combined sources12
Beta strandi112 – 123Combined sources12
Helixi124 – 134Combined sources11
Helixi140 – 144Combined sources5
Helixi149 – 155Combined sources7
Beta strandi160 – 166Combined sources7
Helixi173 – 191Combined sources19
Helixi197 – 204Combined sources8
Helixi205 – 207Combined sources3
Beta strandi218 – 224Combined sources7
Turni225 – 227Combined sources3
Beta strandi228 – 233Combined sources6
Beta strandi236 – 242Combined sources7
Helixi244 – 255Combined sources12
Beta strandi256 – 258Combined sources3
Helixi262 – 275Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DOOX-ray1.90A/B74-278[»]
ProteinModelPortaliQ9M1X2
SMRiQ9M1X2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone isomerase family.Curated

Phylogenomic databases

eggNOGiENOG410IH7M Eukaryota
ENOG410Y0PD LUCA
HOGENOMiHOG000242388
InParanoidiQ9M1X2
OMAiPWGSITL
OrthoDBiEOG09360M5K
PhylomeDBiQ9M1X2

Family and domain databases

Gene3Di1.10.890.20, 2 hits
InterProiView protein in InterPro
IPR016087 Chalcone_isomerase
IPR016089 Chalcone_isomerase_bundle_sf
IPR036298 Chalcone_isomerase_sf
PfamiView protein in Pfam
PF16035 Chalcone_2, 1 hit
SUPFAMiSSF54626 SSF54626, 1 hit

Sequencei

Sequence statusi: Complete.

Q9M1X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSFRFPFSF SQPPRATTSF SGFSISAVAV SVTVGAAAAG AAIAASRNPS
60 70 80 90 100
HPILEWAFSS HRSSLSPWGS ITLADESVVE PKTGFSFPAS IGDSRRLLGV
110 120 130 140 150
GLRKKSLLGL KNIDVYAFGV YADCDDVKKL VGDKYANLPA SEIRGNKSFM
160 170 180 190 200
DDLMEADIKM TIRLQIVYGK LNIRSVRNAF QESVGNRLKK FGGSDNDELL
210 220 230 240 250
QSFTSLFKDE YKIPRNSTID LTKDPGHVLS VAIEGNHVGS VKSHLLCRSI
260 270
LDLYIGEEPF DKNAREDFLD NAASLAFDN
Length:279
Mass (Da):30,394
Last modified:October 1, 2000 - v1
Checksum:iF7AECC580FD805D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA Translation: CAB86418.1
CP002686 Genomic DNA Translation: AEE80443.1
AY065149 mRNA Translation: AAL38325.1
AY081626 mRNA Translation: AAM10188.1
AY088229 mRNA Translation: AAM65770.1
PIRiT48106
RefSeqiNP_567140.1, NM_116182.5
UniGeneiAt.28579
At.48805

Genome annotation databases

EnsemblPlantsiAT3G63170.1; AT3G63170.1; AT3G63170
GeneIDi825492
GrameneiAT3G63170.1; AT3G63170.1; AT3G63170
KEGGiath:AT3G63170

Similar proteinsi

Entry informationi

Entry nameiFAP1_ARATH
AccessioniPrimary (citable) accession number: Q9M1X2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: October 1, 2000
Last modified: May 23, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

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