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Protein

Fatty-acid-binding protein 1

Gene

FAP1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Fatty-acid-binding protein. Interacts preferentially with saturated fatty acid. May be involved in alpha-linolenic (C18:3) metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei103Fatty acid1
Binding sitei116Fatty acid1
Binding sitei183Fatty acid1

GO - Molecular functioni

  • chalcone isomerase activity Source: InterPro
  • fatty acid binding Source: TAIR

GO - Biological processi

  • fatty acid metabolic process Source: TAIR
  • flavonoid biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty-acid-binding protein 1
Short name:
AtFAP1
Alternative name(s):
Chalcone-flavanone isomerase family protein 1
Gene namesi
Name:FAP1
Ordered Locus Names:At3g63170
ORF Names:F16M2.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G63170.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: TAIR
  • chloroplast envelope Source: TAIR
  • chloroplast stroma Source: TAIR
  • mitochondrion Source: TAIR
  • plastid Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

Pathology & Biotechi

Disruption phenotypei

No visible phenotype during vegetative growth, but shorter siliques containing a reduced number of viable seeds. Elevated total fatty-acid levels in leaves and seeds of plants grown at 15 and 22 degrees Celsius.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004220771 – 279Fatty-acid-binding protein 1Add BLAST279

Proteomic databases

PaxDbiQ9M1X2.

PTM databases

iPTMnetiQ9M1X2.

Expressioni

Tissue specificityi

Expressed in developing cotyledons, young seedlings, roots, seeds, embryos, macrospores, preanthesis and tapetum. Restricted to developing and reproductive tissues.1 Publication

Gene expression databases

GenevisibleiQ9M1X2. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G63170.1.

Structurei

Secondary structure

1279
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni81 – 83Combined sources3
Beta strandi89 – 91Combined sources3
Turni92 – 94Combined sources3
Beta strandi95 – 106Combined sources12
Beta strandi112 – 123Combined sources12
Helixi124 – 134Combined sources11
Helixi140 – 144Combined sources5
Helixi149 – 155Combined sources7
Beta strandi160 – 166Combined sources7
Helixi173 – 191Combined sources19
Helixi197 – 204Combined sources8
Helixi205 – 207Combined sources3
Beta strandi218 – 224Combined sources7
Turni225 – 227Combined sources3
Beta strandi228 – 233Combined sources6
Beta strandi236 – 242Combined sources7
Helixi244 – 255Combined sources12
Beta strandi256 – 258Combined sources3
Helixi262 – 275Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DOOX-ray1.90A/B74-278[»]
ProteinModelPortaliQ9M1X2.
SMRiQ9M1X2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone isomerase family.Curated

Phylogenomic databases

eggNOGiENOG410IH7M. Eukaryota.
ENOG410Y0PD. LUCA.
HOGENOMiHOG000242388.
InParanoidiQ9M1X2.
OMAiQFKDEYK.
OrthoDBiEOG09360M5K.
PhylomeDBiQ9M1X2.

Family and domain databases

Gene3Di3.50.70.10. 1 hit.
InterProiIPR016087. Chalcone_isomerase.
IPR016088. Chalcone_isomerase_3-sand.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9M1X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSFRFPFSF SQPPRATTSF SGFSISAVAV SVTVGAAAAG AAIAASRNPS
60 70 80 90 100
HPILEWAFSS HRSSLSPWGS ITLADESVVE PKTGFSFPAS IGDSRRLLGV
110 120 130 140 150
GLRKKSLLGL KNIDVYAFGV YADCDDVKKL VGDKYANLPA SEIRGNKSFM
160 170 180 190 200
DDLMEADIKM TIRLQIVYGK LNIRSVRNAF QESVGNRLKK FGGSDNDELL
210 220 230 240 250
QSFTSLFKDE YKIPRNSTID LTKDPGHVLS VAIEGNHVGS VKSHLLCRSI
260 270
LDLYIGEEPF DKNAREDFLD NAASLAFDN
Length:279
Mass (Da):30,394
Last modified:October 1, 2000 - v1
Checksum:iF7AECC580FD805D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86418.1.
CP002686 Genomic DNA. Translation: AEE80443.1.
AY065149 mRNA. Translation: AAL38325.1.
AY081626 mRNA. Translation: AAM10188.1.
AY088229 mRNA. Translation: AAM65770.1.
PIRiT48106.
RefSeqiNP_567140.1. NM_116182.5.
UniGeneiAt.28579.
At.48805.

Genome annotation databases

EnsemblPlantsiAT3G63170.1; AT3G63170.1; AT3G63170.
GeneIDi825492.
GrameneiAT3G63170.1; AT3G63170.1; AT3G63170.
KEGGiath:AT3G63170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86418.1.
CP002686 Genomic DNA. Translation: AEE80443.1.
AY065149 mRNA. Translation: AAL38325.1.
AY081626 mRNA. Translation: AAM10188.1.
AY088229 mRNA. Translation: AAM65770.1.
PIRiT48106.
RefSeqiNP_567140.1. NM_116182.5.
UniGeneiAt.28579.
At.48805.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4DOOX-ray1.90A/B74-278[»]
ProteinModelPortaliQ9M1X2.
SMRiQ9M1X2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G63170.1.

PTM databases

iPTMnetiQ9M1X2.

Proteomic databases

PaxDbiQ9M1X2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G63170.1; AT3G63170.1; AT3G63170.
GeneIDi825492.
GrameneiAT3G63170.1; AT3G63170.1; AT3G63170.
KEGGiath:AT3G63170.

Organism-specific databases

TAIRiAT3G63170.

Phylogenomic databases

eggNOGiENOG410IH7M. Eukaryota.
ENOG410Y0PD. LUCA.
HOGENOMiHOG000242388.
InParanoidiQ9M1X2.
OMAiQFKDEYK.
OrthoDBiEOG09360M5K.
PhylomeDBiQ9M1X2.

Miscellaneous databases

PROiQ9M1X2.

Gene expression databases

GenevisibleiQ9M1X2. AT.

Family and domain databases

Gene3Di3.50.70.10. 1 hit.
InterProiIPR016087. Chalcone_isomerase.
IPR016088. Chalcone_isomerase_3-sand.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFAP1_ARATH
AccessioniPrimary (citable) accession number: Q9M1X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.