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Protein

Fatty-acid-binding protein 1

Gene

FAP1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

Fatty-acid-binding protein. Interacts preferentially with saturated fatty acid. May be involved in alpha-linolenic (C18:3) metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei103 – 1031Fatty acid
Binding sitei116 – 1161Fatty acid
Binding sitei183 – 1831Fatty acid

GO - Molecular functioni

  • chalcone isomerase activity Source: InterPro
  • fatty acid binding Source: TAIR

GO - Biological processi

  • fatty acid metabolic process Source: TAIR
  • flavonoid biosynthetic process Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Fatty-acid-binding protein 1
Short name:
AtFAP1
Alternative name(s):
Chalcone-flavanone isomerase family protein 1
Gene namesi
Name:FAP1
Ordered Locus Names:At3g63170
ORF Names:F16M2.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G63170.

Subcellular locationi

GO - Cellular componenti

  • chloroplast Source: TAIR
  • chloroplast envelope Source: TAIR
  • chloroplast stroma Source: TAIR
  • mitochondrion Source: TAIR
  • plastid Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

Pathology & Biotechi

Disruption phenotypei

No visible phenotype during vegetative growth, but shorter siliques containing a reduced number of viable seeds. Elevated total fatty-acid levels in leaves and seeds of plants grown at 15 and 22 degrees Celsius.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 279279Fatty-acid-binding protein 1PRO_0000422077Add
BLAST

Proteomic databases

PaxDbiQ9M1X2.
PRIDEiQ9M1X2.

PTM databases

iPTMnetiQ9M1X2.

Expressioni

Tissue specificityi

Expressed in developing cotyledons, young seedlings, roots, seeds, embryos, macrospores, preanthesis and tapetum. Restricted to developing and reproductive tissues.1 Publication

Gene expression databases

GenevisibleiQ9M1X2. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT3G63170.1.

Structurei

Secondary structure

1
279
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Turni81 – 833Combined sources
Beta strandi89 – 913Combined sources
Turni92 – 943Combined sources
Beta strandi95 – 10612Combined sources
Beta strandi112 – 12312Combined sources
Helixi124 – 13411Combined sources
Helixi140 – 1445Combined sources
Helixi149 – 1557Combined sources
Beta strandi160 – 1667Combined sources
Helixi173 – 19119Combined sources
Helixi197 – 2048Combined sources
Helixi205 – 2073Combined sources
Beta strandi218 – 2247Combined sources
Turni225 – 2273Combined sources
Beta strandi228 – 2336Combined sources
Beta strandi236 – 2427Combined sources
Helixi244 – 25512Combined sources
Beta strandi256 – 2583Combined sources
Helixi262 – 27514Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DOOX-ray1.90A/B74-278[»]
ProteinModelPortaliQ9M1X2.
SMRiQ9M1X2. Positions 76-278.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone isomerase family.Curated

Phylogenomic databases

eggNOGiENOG410IH7M. Eukaryota.
ENOG410Y0PD. LUCA.
HOGENOMiHOG000242388.
InParanoidiQ9M1X2.
OMAiQFKDEYK.
OrthoDBiEOG09360M5K.
PhylomeDBiQ9M1X2.

Family and domain databases

Gene3Di3.50.70.10. 1 hit.
InterProiIPR016087. Chalcone_isomerase.
IPR016088. Chalcone_isomerase_3-sand.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9M1X2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSFRFPFSF SQPPRATTSF SGFSISAVAV SVTVGAAAAG AAIAASRNPS
60 70 80 90 100
HPILEWAFSS HRSSLSPWGS ITLADESVVE PKTGFSFPAS IGDSRRLLGV
110 120 130 140 150
GLRKKSLLGL KNIDVYAFGV YADCDDVKKL VGDKYANLPA SEIRGNKSFM
160 170 180 190 200
DDLMEADIKM TIRLQIVYGK LNIRSVRNAF QESVGNRLKK FGGSDNDELL
210 220 230 240 250
QSFTSLFKDE YKIPRNSTID LTKDPGHVLS VAIEGNHVGS VKSHLLCRSI
260 270
LDLYIGEEPF DKNAREDFLD NAASLAFDN
Length:279
Mass (Da):30,394
Last modified:October 1, 2000 - v1
Checksum:iF7AECC580FD805D1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86418.1.
CP002686 Genomic DNA. Translation: AEE80443.1.
AY065149 mRNA. Translation: AAL38325.1.
AY081626 mRNA. Translation: AAM10188.1.
AY088229 mRNA. Translation: AAM65770.1.
PIRiT48106.
RefSeqiNP_567140.1. NM_116182.4.
UniGeneiAt.28579.
At.48805.

Genome annotation databases

EnsemblPlantsiAT3G63170.1; AT3G63170.1; AT3G63170.
GeneIDi825492.
GrameneiAT3G63170.1; AT3G63170.1; AT3G63170.
KEGGiath:AT3G63170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138648 Genomic DNA. Translation: CAB86418.1.
CP002686 Genomic DNA. Translation: AEE80443.1.
AY065149 mRNA. Translation: AAL38325.1.
AY081626 mRNA. Translation: AAM10188.1.
AY088229 mRNA. Translation: AAM65770.1.
PIRiT48106.
RefSeqiNP_567140.1. NM_116182.4.
UniGeneiAt.28579.
At.48805.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4DOOX-ray1.90A/B74-278[»]
ProteinModelPortaliQ9M1X2.
SMRiQ9M1X2. Positions 76-278.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT3G63170.1.

PTM databases

iPTMnetiQ9M1X2.

Proteomic databases

PaxDbiQ9M1X2.
PRIDEiQ9M1X2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G63170.1; AT3G63170.1; AT3G63170.
GeneIDi825492.
GrameneiAT3G63170.1; AT3G63170.1; AT3G63170.
KEGGiath:AT3G63170.

Organism-specific databases

TAIRiAT3G63170.

Phylogenomic databases

eggNOGiENOG410IH7M. Eukaryota.
ENOG410Y0PD. LUCA.
HOGENOMiHOG000242388.
InParanoidiQ9M1X2.
OMAiQFKDEYK.
OrthoDBiEOG09360M5K.
PhylomeDBiQ9M1X2.

Miscellaneous databases

PROiQ9M1X2.

Gene expression databases

GenevisibleiQ9M1X2. AT.

Family and domain databases

Gene3Di3.50.70.10. 1 hit.
InterProiIPR016087. Chalcone_isomerase.
IPR016088. Chalcone_isomerase_3-sand.
[Graphical view]
PfamiPF16035. Chalcone_2. 1 hit.
[Graphical view]
SUPFAMiSSF54626. SSF54626. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFAP1_ARATH
AccessioniPrimary (citable) accession number: Q9M1X2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2013
Last sequence update: October 1, 2000
Last modified: September 7, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.