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Q9M1K2 (PI5K4_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 4-phosphate 5-kinase 4
Short name=AtPIP5K4
EC=2.7.1.68
Alternative name(s):
1-phosphatidylinositol 4-phosphate kinase 4
Diphosphoinositide kinase 4
PtdIns(4)P-5-kinase 4
Gene names
Name:PIP5K4
Ordered Locus Names:At3g56960
ORF Names:F24I3.40
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length779 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

Sequence similarities

Contains 8 MORN repeats.

Contains 1 PIPK domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 779779Phosphatidylinositol 4-phosphate 5-kinase 4
PRO_0000185476

Regions

Repeat77 – 9923MORN 1
Repeat100 – 12223MORN 2
Repeat123 – 14523MORN 3
Repeat146 – 16823MORN 4
Repeat169 – 19123MORN 5
Repeat192 – 21423MORN 6
Repeat215 – 23723MORN 7
Repeat238 – 25922MORN 8
Domain382 – 775394PIPK
Region735 – 75622Activation loop By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9M1K2 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: FAEB3BF1603C18B0

FASTA77989,238
        10         20         30         40         50         60 
MSKEQSCVLK AWEVTVRKTQ QAKKRANSIF GTVSVAPQTD DDATTTTEEN DDETSTNRSS 

        70         80         90        100        110        120 
IGELYHAERI LPNGDYYTGQ WYDSFPHGHG KYLWTDGCMY IGDWYNGKTM GRGKFGWPSG 

       130        140        150        160        170        180 
ATYEGEFKSG YMDGVGLYTG PSGDTYKGQW VMNLKHGHGI KRFANGDVYD GEWRRGLQEA 

       190        200        210        220        230        240 
QGKYQWRDGS YYMGEWKNAT ICGKGTFIWT DGNRYDGFWD DGFPRGNGTF KWADGSFYVG 

       250        260        270        280        290        300 
HWSNDPEEMN GTYYPSGDDG SPEWDPKDVF TNLSEYKICS GERVPVLPSQ KKLSVWNSSK 

       310        320        330        340        350        360 
RVEKPRRMSV DGRVSVGVDR AFEKMNMWGT ESGEGAADID STTRRDLDAE MMRLEAEGFI 

       370        380        390        400        410        420 
QSLRPSPAPM RLPRAGRKQG ETISKGHRNY ELMLNLQLGI RHAVGKQAPV VSLDLKHSAF 

       430        440        450        460        470        480 
DPKEKVWTRF PPEGTKYTPP HQSSEFKWKD YCPLVFRSLR KLFKVDPADY MLSICGNDAL 

       490        500        510        520        530        540 
RELSSPGKSG SFFYLTNDDR YMIKTMKKSE TKVLLRMLAA YYNHVRAFEN TLVIRFYGLH 

       550        560        570        580        590        600 
CVKLTGPIQK KVRFVIMGNL FCSEYSIHRR FDLKGSSLGR TTDKPESEIN SNTILKDLDL 

       610        620        630        640        650        660 
NFIFRLQKAW YQEFIRQVDK DCEFLEQERI MDYSLLVGIH FREASVAGEL IPSGARTPIG 

       670        680        690        700        710        720 
EFEDESAPRL SRADVDQLLS DPTRWASIRL GGNMPARAER TMRRSDCEFQ LVGEPTGEYY 

       730        740        750        760        770 
EVVMIFGIID ILQDYDISKK LEHAYKSIQY DPTSISAVDP RLYSRRFRDF IFKVFTEDN

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana."
Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B., Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M., Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V., Choisne N., Artiguenave F. expand/collapse author list , Robert C., Brottier P., Wincker P., Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H., Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H., Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A., Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H., Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J., Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B., Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D., de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E., Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G., Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X., Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M., Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B., Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J., Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C., Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y., Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K., Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
Nature 408:820-822(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
Mueller-Roeber B., Pical C.
Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: GENE FAMILY, NOMENCLATURE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL138655 Genomic DNA. Translation: CAB72166.1.
CP002686 Genomic DNA. Translation: AEE79593.1.
IPIIPI00523818.
PIRT47756.
RefSeqNP_191255.1. NM_115555.1.
UniGeneAt.53961.

3D structure databases

ProteinModelPortalQ9M1K2.
SMRQ9M1K2. Positions 396-640.
ModBaseSearch...

Protein-protein interaction databases

MINTMINT-8069801.
STRING3702.AT3G56960.1-P.

Proteomic databases

PaxDbQ9M1K2.
PRIDEQ9M1K2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT3G56960.1; AT3G56960.1; AT3G56960.
GeneID824863.
KEGGath:AT3G56960.

Organism-specific databases

TAIRAt3g56960.

Phylogenomic databases

eggNOGCOG4642.
HOGENOMHOG000193875.
InParanoidQ9M1K2.
KOK00889.
OMAGKTMGRG.
PhylomeDBQ9M1K2.
ProtClustDBCLSN2683759.

Gene expression databases

GenevestigatorQ9M1K2.
GermOnlineAT3G56960. Arabidopsis thaliana.

Family and domain databases

Gene3D3.30.800.10. 1 hit.
3.30.810.10. 2 hits.
InterProIPR003409. MORN.
IPR017163. PIno-4-P-5_kinase_pln.
IPR023610. PInositol-4-P-5-kinase.
IPR027483. PInositol-4-P-5-kinase_C.
IPR002498. PInositol-4-P-5-kinase_core.
IPR027484. PInositol-4-P-5-kinase_N.
IPR016034. PInositol-4P-5-kinase_core_sub.
[Graphical view]
PANTHERPTHR23086. PTHR23086. 1 hit.
PfamPF02493. MORN. 8 hits.
PF01504. PIP5K. 1 hit.
[Graphical view]
PIRSFPIRSF037274. PIP5K_plant_prd. 1 hit.
SMARTSM00698. MORN. 7 hits.
SM00330. PIPKc. 1 hit.
[Graphical view]
PROSITEPS51455. PIPK. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI5K4_ARATH
AccessionPrimary (citable) accession number: Q9M1K2
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: October 1, 2000
Last modified: May 29, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents