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Q9M149

- PI5KB_ARATH

UniProt

Q9M149 - PI5KB_ARATH

Protein

Putative phosphatidylinositol 4-phosphate 5-kinase 11

Gene

PIP5K11

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.

    GO - Molecular functioni

    1. 1-phosphatidylinositol-4-phosphate 5-kinase activity Source: TAIR
    2. ATP binding Source: UniProtKB-KW

    GO - Biological processi

    1. phosphatidylinositol phosphorylation Source: GOC

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciARA:AT4G01190-MONOMER.
    ReactomeiREACT_187642. Synthesis of PIPs at the plasma membrane.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative phosphatidylinositol 4-phosphate 5-kinase 11 (EC:2.7.1.68)
    Short name:
    AtPIP5K11
    Alternative name(s):
    1-phosphatidylinositol 4-phosphate kinase 11
    Diphosphoinositide kinase 11
    PtdIns(4)P-5-kinase 11
    Gene namesi
    Name:PIP5K11
    Ordered Locus Names:At4g01190
    ORF Names:F2N1.9
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 4

    Organism-specific databases

    TAIRiAT4G01190.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Putative phosphatidylinositol 4-phosphate 5-kinase 11PRO_0000185483Add
    BLAST

    Proteomic databases

    PRIDEiQ9M149.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9M149.

    Interactioni

    Protein-protein interaction databases

    BioGridi13357. 4 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9M149.
    SMRiQ9M149. Positions 27-235.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini1 – 390390PIPKPROSITE-ProRule annotationAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni350 – 37122Activation loopBy similarityAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi241 – 29353Ser-richAdd
    BLAST

    Sequence similaritiesi

    Contains 1 PIPK domain.PROSITE-ProRule annotation

    Phylogenomic databases

    eggNOGiCOG5253.
    HOGENOMiHOG000193875.
    InParanoidiQ9M149.
    KOiK00889.
    OMAiNRIRYST.
    PhylomeDBiQ9M149.

    Family and domain databases

    Gene3Di3.30.800.10. 1 hit.
    3.30.810.10. 2 hits.
    InterProiIPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view]
    PANTHERiPTHR23086. PTHR23086. 1 hit.
    PfamiPF01504. PIP5K. 1 hit.
    [Graphical view]
    SMARTiSM00330. PIPKc. 1 hit.
    [Graphical view]
    PROSITEiPS51455. PIPK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9M149-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELRATVENR IRYSTKHIKH LPPGSITEFD WKDYCPVGFG LIQELEGIDH    50
    DDYLLSICTD ETLKKISSGK IGNVFHISND NRFLIKILRK SEIKVTLEML 100
    PRYYRHINYH RSSLFTRIFG AHSVKPLGGV KTYFAVMSNM LHSTIFVNKL 150
    YDLKGSPKGR SNKKIEVRNT TVLKDIDFDF CFYVDPLARQ RIIKQTKLDC 200
    ELLEEEGIMD YSLLVGLQSK GSCQGSLDGL NPVYGSFAPP SSFKSNSTKS 250
    MKTASSSPDR SSVAMYSCSP DRDSVENEMS MTIQSVTSNS ASSETNILAT 300
    TLSDLFHNSS NINFGMKIPA RARRVTRETG EEEWYNVVLY IGIVDTFQDY 350
    GMKKRIEHCY KSIQYNSNSI STVHPKIYSS RFQDFVSNIF LPHDDDLSSK 400
    Y 401
    Length:401
    Mass (Da):45,659
    Last modified:October 1, 2000 - v1
    Checksum:i8A12D10DA2DED4CA
    GO

    Sequence cautioni

    The sequence AAB61030.1 differs from that shown. Reason: Erroneous gene model prediction.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF007269 Genomic DNA. Translation: AAB61030.1. Sequence problems.
    AL161491 Genomic DNA. Translation: CAB80928.1.
    CP002687 Genomic DNA. Translation: AEE81992.1.
    PIRiF85015.
    T01723.
    RefSeqiNP_192028.1. NM_116349.1.
    UniGeneiAt.54072.

    Genome annotation databases

    EnsemblPlantsiAT4G01190.1; AT4G01190.1; AT4G01190.
    GeneIDi828066.
    KEGGiath:AT4G01190.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF007269 Genomic DNA. Translation: AAB61030.1 . Sequence problems.
    AL161491 Genomic DNA. Translation: CAB80928.1 .
    CP002687 Genomic DNA. Translation: AEE81992.1 .
    PIRi F85015.
    T01723.
    RefSeqi NP_192028.1. NM_116349.1.
    UniGenei At.54072.

    3D structure databases

    ProteinModelPortali Q9M149.
    SMRi Q9M149. Positions 27-235.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 13357. 4 interactions.

    Proteomic databases

    PRIDEi Q9M149.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT4G01190.1 ; AT4G01190.1 ; AT4G01190 .
    GeneIDi 828066.
    KEGGi ath:AT4G01190.

    Organism-specific databases

    TAIRi AT4G01190.

    Phylogenomic databases

    eggNOGi COG5253.
    HOGENOMi HOG000193875.
    InParanoidi Q9M149.
    KOi K00889.
    OMAi NRIRYST.
    PhylomeDBi Q9M149.

    Enzyme and pathway databases

    BioCyci ARA:AT4G01190-MONOMER.
    Reactomei REACT_187642. Synthesis of PIPs at the plasma membrane.

    Miscellaneous databases

    PROi Q9M149.

    Gene expression databases

    Genevestigatori Q9M149.

    Family and domain databases

    Gene3Di 3.30.800.10. 1 hit.
    3.30.810.10. 2 hits.
    InterProi IPR023610. PInositol-4-P-5-kinase.
    IPR027483. PInositol-4-P-5-kinase_C.
    IPR002498. PInositol-4-P-5-kinase_core.
    IPR027484. PInositol-4-P-5-kinase_N.
    IPR016034. PInositol-4P-5-kinase_core_sub.
    [Graphical view ]
    PANTHERi PTHR23086. PTHR23086. 1 hit.
    Pfami PF01504. PIP5K. 1 hit.
    [Graphical view ]
    SMARTi SM00330. PIPKc. 1 hit.
    [Graphical view ]
    PROSITEi PS51455. PIPK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana."
      Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B.
      , Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.
      Nature 402:769-777(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C."
      Mueller-Roeber B., Pical C.
      Plant Physiol. 130:22-46(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiPI5KB_ARATH
    AccessioniPrimary (citable) accession number: Q9M149
    Secondary accession number(s): O04613
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 25, 2005
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 85 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3