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Protein

ABC transporter B family member 9

Gene

ABCB9

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi390 – 397ATPPROSITE-ProRule annotation8
Nucleotide bindingi1028 – 1035ATPPROSITE-ProRule annotation8

GO - Molecular functioni

Keywordsi

Biological processTransport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-159418 Recycling of bile acids and salts
R-ATH-193368 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
R-ATH-382556 ABC-family proteins mediated transport

Names & Taxonomyi

Protein namesi
Recommended name:
ABC transporter B family member 9
Short name:
ABC transporter ABCB.9
Short name:
AtABCB9
Alternative name(s):
Multidrug resistance protein 9
P-glycoprotein 9
Gene namesi
Name:ABCB9
Synonyms:MDR9, PGP9
Ordered Locus Names:At4g18050
ORF Names:F15J5.20
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G18050
TAIRilocus:2117656 AT4G18050

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei38 – 58HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei80 – 100HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei158 – 178HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei179 – 199HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei257 – 277HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei288 – 308HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei685 – 705HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei725 – 745HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei785 – 805HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei806 – 826HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei902 – 922HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei927 – 947HelicalPROSITE-ProRule annotationAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002279201 – 1236ABC transporter B family member 9Add BLAST1236

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi542N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi631N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi653N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1082N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1181N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiQ9M0M2
PRIDEiQ9M0M2

Expressioni

Gene expression databases

ExpressionAtlasiQ9M0M2 baseline and differential
GenevisibleiQ9M0M2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G18050.1

Structurei

3D structure databases

ProteinModelPortaliQ9M0M2
SMRiQ9M0M2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 320ABC transmembrane type-1 1PROSITE-ProRule annotationAdd BLAST288
Domaini355 – 591ABC transporter 1PROSITE-ProRule annotationAdd BLAST237
Domaini686 – 958ABC transmembrane type-1 2PROSITE-ProRule annotationAdd BLAST273
Domaini993 – 1230ABC transporter 2PROSITE-ProRule annotationAdd BLAST238

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0055 Eukaryota
COG1132 LUCA
InParanoidiQ9M0M2
KOiK05658
OMAiFNGENRA
OrthoDBiEOG093600JM

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 2 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 2 hits
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q9M0M2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEKSSKKND GGNQKVSFFK LFSFADKTDV VLMTVGTIAA AGNGLTQPFM
60 70 80 90 100
TLIFGQLINA FGTTDPDHMV REVWKVAVKF IYLAVYSCVV AFLQVSCWMV
110 120 130 140 150
TGERQSATIR GLYLKTILRQ DIGYFDTETN TGEVIGRMSG DTILIQDAMG
160 170 180 190 200
EKVGKFTQLL CTFLGGFAIA FYKGPLLAGV LCSCIPLIVI AGAAMSLIMS
210 220 230 240 250
KMAGRGQVAY AEAGNVVEQT VGAIRTVVAF TGEKQATEKY ESKLEIAYKT
260 270 280 290 300
VVQQGLISGF GLGTMLAVIF CSYGLAVWYG AKLIMEKGYN GGQVINVIFA
310 320 330 340 350
VLTGGMSLGQ TSPSLNAFAA GRAAAFKMFE TIKRSPKIDA YDMSGSVLED
360 370 380 390 400
IRGDIELKDV YFRYPARPDV QIFAGFSLFV PNGKTVALVG QSGSGKSTVI
410 420 430 440 450
SLIERFYDPE SGQVLIDNID LKKLQLKWIR SKIGLVSQEP VLFATTIKEN
460 470 480 490 500
IAYGKEDATD QEIRTAIELA NAAKFIDKLP QGLDTMVGEH GTQMSGGQKQ
510 520 530 540 550
RLAIARAILK NPKILLLDEA TSALDAESER IVQDALVNLM SNRTTVVVAH
560 570 580 590 600
RLTTIRTADV IAVVHQGKIV EKGTHDEMIQ DPEGAYSQLV RLQEGSKEEA
610 620 630 640 650
TESERPETSL DVERSGSLRL SSAMRRSVSR NSSSSRHSFS LASNMFFPGV
660 670 680 690 700
NVNQTDEMED EENNVRHKKV SLKRLAHLNK PEIPVLVLGS IAAMVHGTVF
710 720 730 740 750
PIFGLLLSSS INMFYEPAKI LKKDSHFWAL IYIALGLTNF VMIPVQNYFF
760 770 780 790 800
GIAGGKLIKR IRSMCFDKVV HQEISWFDDT ANSRSLVGDA LALIVQNIAT
810 820 830 840 850
VTTGLIIAFT ANWILALIVL ALSPFIVIQG YAQTKFLTGF SADAKAMYEE
860 870 880 890 900
ASQVANDAVS SIRTVASFCA EEKVMDLYQQ KCDGPKKNGV RLGLLSGAGF
910 920 930 940 950
GFSFFFLYCI NCVCFVSGAG LIQIGKATFG EVFKVFFALT IMAIGVSQTS
960 970 980 990 1000
AMAPDSNKAK DSAASIFDIL DSTPKIDSSS DEGTTLQNVN GDIEFRHVSF
1010 1020 1030 1040 1050
RYPMRPDVQI FRDLCLTIPS GKTVALVGES GSGKSTVISM IERFYNPDSG
1060 1070 1080 1090 1100
KILIDQVEIQ TFKLSWLRQQ MGLVSQEPIL FNETIRSNIA YGKTGGATEE
1110 1120 1130 1140 1150
EIIAAAKAAN AHNFISSLPQ GYDTSVGERG VQLSGGQKQR IAIARAILKD
1160 1170 1180 1190 1200
PKILLLDEAT SALDAESERV VQDALDRVMV NRTTVVVAHR LTTIKNADVI
1210 1220 1230
AVVKNGVIAE KGRHETLMKI SGGAYASLVT LHMSAN
Length:1,236
Mass (Da):134,366
Last modified:February 22, 2012 - v2
Checksum:i998787871DDC4489
GO

Sequence cautioni

The sequence CAB53646 differs from that shown. Reason: Frameshift at position 1218.Curated
The sequence CAB53646 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence CAB78807 differs from that shown. Reason: Frameshift at position 1218.Curated
The sequence CAB78807 differs from that shown. Reason: Erroneous gene model prediction.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti746Q → P in CAB53646 (PubMed:10617198).Curated1
Sequence conflicti746Q → P in CAB78807 (PubMed:10617198).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL110123 Genomic DNA Translation: CAB53646.1 Sequence problems.
AL161547 Genomic DNA Translation: CAB78807.1 Sequence problems.
CP002687 Genomic DNA Translation: AEE83988.1
PIRiH85202
T14805
RefSeqiNP_193539.6, NM_117915.7
UniGeneiAt.54385

Genome annotation databases

EnsemblPlantsiAT4G18050.1; AT4G18050.1; AT4G18050
GeneIDi827530
GrameneiAT4G18050.1; AT4G18050.1; AT4G18050
KEGGiath:AT4G18050

Similar proteinsi

Entry informationi

Entry nameiAB9B_ARATH
AccessioniPrimary (citable) accession number: Q9M0M2
Secondary accession number(s): F4JQQ3, Q9SVW6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: February 22, 2012
Last modified: April 25, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health