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Protein

Probable xyloglucan endotransglucosylase/hydrolase protein 18

Gene

XTH18

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalyzes xyloglucan endohydrolysis (XEH) and/or endotransglycosylation (XET). Cleaves and religates xyloglucan polymers, an essential constituent of the primary cell wall, and thereby participates in cell wall construction of growing tissues (By similarity).By similarity

Catalytic activityi

Breaks a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei104NucleophilePROSITE-ProRule annotation1
Active sitei108Proton donorPROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

  • cell wall biogenesis Source: InterPro
  • cell wall organization Source: UniProtKB-KW
  • xyloglucan metabolic process Source: TAIR

Keywordsi

Molecular functionGlycosidase, Hydrolase, Transferase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciARA:AT4G30280-MONOMER
BRENDAi2.4.1.207 399

Protein family/group databases

CAZyiGH16 Glycoside Hydrolase Family 16

Names & Taxonomyi

Protein namesi
Recommended name:
Probable xyloglucan endotransglucosylase/hydrolase protein 18 (EC:2.4.1.207)
Short name:
At-XTH18
Short name:
XTH-18
Gene namesi
Name:XTH18
Ordered Locus Names:At4g30280
ORF Names:F17I23.380
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G30280
TAIRilocus:2118746 AT4G30280

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Apoplast, Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 26Sequence analysisAdd BLAST26
ChainiPRO_000001181827 – 282Probable xyloglucan endotransglucosylase/hydrolase protein 18Add BLAST256

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi112N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi238N-linked (GlcNAc...) asparagineSequence analysis1

Post-translational modificationi

Contains at least one intrachain disulfide bond essential for its enzymatic activity.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiQ9M0D2

Expressioni

Tissue specificityi

Root specific.1 Publication

Gene expression databases

ExpressionAtlasiQ9M0D2 baseline and differential
GenevisibleiQ9M0D2 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT4G30280.1

Structurei

3D structure databases

ProteinModelPortaliQ9M0D2
SMRiQ9M0D2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 218GH16PROSITE-ProRule annotationAdd BLAST192

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IHDJ Eukaryota
COG2273 LUCA
HOGENOMiHOG000236368
InParanoidiQ9M0D2
KOiK08235
OMAiNLSGHPY
OrthoDBiEOG093614VA
PhylomeDBiQ9M0D2

Family and domain databases

InterProiView protein in InterPro
IPR008264 Beta_glucanase
IPR013320 ConA-like_dom_sf
IPR000757 GH16
IPR008263 GH16_AS
IPR010713 XET_C
IPR016455 XTH
PfamiView protein in Pfam
PF00722 Glyco_hydro_16, 1 hit
PF06955 XET_C, 1 hit
PIRSFiPIRSF005604 XET, 1 hit
PRINTSiPR00737 GLHYDRLASE16
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01034 GH16_1, 1 hit
PS51762 GH16_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9M0D2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSCGTSFA FLIMFLFAAQ SMHVYAGSFH KDVQIHWGDG RGKVRDRDGK
60 70 80 90 100
LLSLSLDKSS GSGFQSNQEF LYGKAEVQMK LVPGNSAGTV TTFYLKSPGT
110 120 130 140 150
TWDEIDFEFL GNLSGHPYTL HTNVYTKGSG DKEQQFHLWF DPTVNFHTYC
160 170 180 190 200
ITWNPQRIIF TVDGIPIREF KNSESIGVPF PTKQPMRLYA SLWEAEHWAT
210 220 230 240 250
RGGLEKTDWS KAPFTAFYRN YNVEGCVWAN GKSSCPANSS WFTQQLDSNG
260 270 280
QTRMKGVQSK YMVYNYCNDK RRFPRGVPVE CS
Length:282
Mass (Da):32,072
Last modified:October 1, 2000 - v1
Checksum:i437B3AC683F71B31
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF083779 mRNA Translation: AAN60337.1
AL161576 Genomic DNA Translation: CAB81021.1
CP002687 Genomic DNA Translation: AEE85746.1
AF419549 mRNA Translation: AAL31883.1
AY097337 mRNA Translation: AAM19853.1
AY085267 mRNA Translation: AAM62499.1
PIRiA85354
RefSeqiNP_194757.1, NM_119174.2
UniGeneiAt.27397

Genome annotation databases

EnsemblPlantsiAT4G30280.1; AT4G30280.1; AT4G30280
GeneIDi829151
GrameneiAT4G30280.1; AT4G30280.1; AT4G30280
KEGGiath:AT4G30280

Similar proteinsi

Entry informationi

Entry nameiXTH18_ARATH
AccessioniPrimary (citable) accession number: Q9M0D2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: October 1, 2000
Last modified: April 25, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health