Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Eukaryotic translation initiation factor 6-2

Gene

EIF6-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis, Ribosome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 6-2UniRule annotation
Short name:
AteIF-6;2
Gene namesi
Name:EIF6-2UniRule annotation
Synonyms:EMB1624
Ordered Locus Names:At3g55620
ORF Names:F1I16.30
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 3

Organism-specific databases

TAIRiAT3G55620.

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Nucleusnucleolus UniRule annotation

  • Note: Shuttles between cytoplasm and nucleus/nucleolus.UniRule annotation

GO - Cellular componenti

  • cytosol Source: TAIR
  • nucleolus Source: TAIR
  • nucleus Source: TAIR
  • preribosome, large subunit precursor Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004020981 – 245Eukaryotic translation initiation factor 6-2Add BLAST245

Proteomic databases

PaxDbiQ9M060.
PRIDEiQ9M060.

PTM databases

iPTMnetiQ9M060.

Expressioni

Inductioni

Expressed at very low levels only.1 Publication

Gene expression databases

GenevisibleiQ9M060. AT.

Interactioni

Subunit structurei

Monomer. Associates with the 60S ribosomal subunit.UniRule annotation

Protein-protein interaction databases

BioGridi10044. 1 interactor.
STRINGi3702.AT3G55620.1.

Structurei

3D structure databases

ProteinModelPortaliQ9M060.
SMRiQ9M060.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3185. Eukaryota.
COG1976. LUCA.
HOGENOMiHOG000230605.
InParanoidiQ9M060.
KOiK03264.
OMAiNDWCAFT.
OrthoDBiEOG09360JT2.
PhylomeDBiQ9M060.

Family and domain databases

CDDicd00527. IF6. 1 hit.
HAMAPiMF_00032. eIF_6. 1 hit.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9M060-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATRLQFENN CEVGVFSKLT NAYCLVAIGG SENFYSAFES ELADVIPIVK
60 70 80 90 100
TSIGGTRIIG RLCAGNKNGL LVPHTTTDQE LQHLRNSLPD QVVVQRIDER
110 120 130 140 150
LSALGNCIAC NDYVALAHTD LDKETEEIIA DVLGVEVFRQ TIAGNILVGS
160 170 180 190 200
YCALSNKGGM VHPHTSVEDL EELSTLLQVP LVAGTVNRGS EVIAAGMTVN
210 220 230 240
DWTSFCGSDT TATELSVIDS IFKLREAQPS SIVDEMRKSL IDTYV
Length:245
Mass (Da):26,482
Last modified:October 1, 2000 - v1
Checksum:i73369A2A657F390D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY128351 mRNA. Translation: AAM91554.1.
BT009656 mRNA. Translation: AAP75806.1.
AL161667 Genomic DNA. Translation: CAB81587.1.
CP002686 Genomic DNA. Translation: AEE79410.1.
PIRiT47701.
RefSeqiNP_191121.1. NM_115420.4.
UniGeneiAt.23205.

Genome annotation databases

EnsemblPlantsiAT3G55620.1; AT3G55620.1; AT3G55620.
GeneIDi824728.
GrameneiAT3G55620.1; AT3G55620.1; AT3G55620.
KEGGiath:AT3G55620.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY128351 mRNA. Translation: AAM91554.1.
BT009656 mRNA. Translation: AAP75806.1.
AL161667 Genomic DNA. Translation: CAB81587.1.
CP002686 Genomic DNA. Translation: AEE79410.1.
PIRiT47701.
RefSeqiNP_191121.1. NM_115420.4.
UniGeneiAt.23205.

3D structure databases

ProteinModelPortaliQ9M060.
SMRiQ9M060.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi10044. 1 interactor.
STRINGi3702.AT3G55620.1.

PTM databases

iPTMnetiQ9M060.

Proteomic databases

PaxDbiQ9M060.
PRIDEiQ9M060.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT3G55620.1; AT3G55620.1; AT3G55620.
GeneIDi824728.
GrameneiAT3G55620.1; AT3G55620.1; AT3G55620.
KEGGiath:AT3G55620.

Organism-specific databases

TAIRiAT3G55620.

Phylogenomic databases

eggNOGiKOG3185. Eukaryota.
COG1976. LUCA.
HOGENOMiHOG000230605.
InParanoidiQ9M060.
KOiK03264.
OMAiNDWCAFT.
OrthoDBiEOG09360JT2.
PhylomeDBiQ9M060.

Miscellaneous databases

PROiQ9M060.

Gene expression databases

GenevisibleiQ9M060. AT.

Family and domain databases

CDDicd00527. IF6. 1 hit.
HAMAPiMF_00032. eIF_6. 1 hit.
InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]
PIRSFiPIRSF006413. IF-6. 1 hit.
SMARTiSM00654. eIF6. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00323. eIF-6. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiIF62_ARATH
AccessioniPrimary (citable) accession number: Q9M060
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 30, 2010
Last sequence update: October 1, 2000
Last modified: November 30, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.