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Protein

Cell division control protein 48 homolog E

Gene

CDC48E

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Probably functions in cell division and growth processes. Interacts with certain SNAREs as part of specialized membrane fusion events where vesicles from the same organelle fuse (homotypic fusion) (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi248 – 255ATPSequence analysis8
Nucleotide bindingi521 – 528ATPSequence analysis8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, Protein transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-ATH-110320 Translesion Synthesis by POLH
R-ATH-382556 ABC-family proteins mediated transport
R-ATH-532668 N-glycan trimming in the ER and Calnexin/Calreticulin cycle
R-ATH-5358346 Hedgehog ligand biogenesis
R-ATH-5689877 Josephin domain DUBs
R-ATH-5689896 Ovarian tumor domain proteases
R-ATH-6798695 Neutrophil degranulation

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division control protein 48 homolog E
Short name:
AtCDC48e
Alternative name(s):
Transitional endoplasmic reticulum ATPase E
Gene namesi
Name:CDC48E
Ordered Locus Names:At5g03340
ORF Names:F12E4_70
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G03340
TAIRilocus:2831844 AT5G03340

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000845832 – 810Cell division control protein 48 homolog EAdd BLAST809

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserineBy similarity1
Modified residuei41PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ9LZF6
PRIDEiQ9LZF6

PTM databases

iPTMnetiQ9LZF6

Expressioni

Gene expression databases

ExpressionAtlasiQ9LZF6 baseline and differential
GenevisibleiQ9LZF6 AT

Interactioni

Protein-protein interaction databases

BioGridi17146, 3 interactors
IntActiQ9LZF6, 1 interactor
STRINGi3702.AT5G03340.1

Structurei

3D structure databases

ProteinModelPortaliQ9LZF6
SMRiQ9LZF6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AAA ATPase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0730 Eukaryota
COG0464 LUCA
HOGENOMiHOG000223224
InParanoidiQ9LZF6
KOiK13525
OMAiQENPDSM
OrthoDBiEOG093602AN
PhylomeDBiQ9LZF6

Family and domain databases

InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR005938 AAA_ATPase_CDC48
IPR009010 Asp_de-COase-like_dom_sf
IPR003959 ATPase_AAA_core
IPR003960 ATPase_AAA_CS
IPR004201 Cdc48_dom2
IPR029067 CDC48_domain_2-like_sf
IPR003338 CDC4_N-term_subdom
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00004 AAA, 2 hits
PF02933 CDC48_2, 1 hit
PF02359 CDC48_N, 1 hit
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SM01072 CDC48_2, 1 hit
SM01073 CDC48_N, 1 hit
SUPFAMiSSF50692 SSF50692, 1 hit
SSF52540 SSF52540, 2 hits
SSF54585 SSF54585, 1 hit
TIGRFAMsiTIGR01243 CDC48, 1 hit
PROSITEiView protein in PROSITE
PS00674 AAA, 2 hits

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9LZF6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNEPESSDS KTKKDFSTAI LERKKSPNRL VVDEAINDDN SVVSLHPTTM
60 70 80 90 100
EKLQLFRGDT ILIKGKKRKD TVCIALADET CEEPKIRMNK VVRSNLRVRL
110 120 130 140 150
GDVISVHQCP DVKYGKRVHI LPVDDTVEGV TGNLFDAYLK PYFLEAYRPV
160 170 180 190 200
RKGDLFLVRG GMRSVEFKVI ETDPAEYCVV APDTEIFCEG EPVKREDEER
210 220 230 240 250
LDEVGYDDVG GVRKQMAQIR ELVELPLRHP QLFKSIGVKP PKGILLYGPP
260 270 280 290 300
GSGKTLIARA VANETGAFFF CINGPEIMSK LAGESESNLR KAFEEAEKNA
310 320 330 340 350
PSIIFIDEID SIAPKREKTN GEVERRIVSQ LLTLMDGLKS RAHVIVMGAT
360 370 380 390 400
NRPNSIDPAL RRFGRFDREI DIGVPDEIGR LEVLRIHTKN MKLAEDVDLE
410 420 430 440 450
RISKDTHGYV GADLAALCTE AALQCIREKM DVIDLEDDSI DAEILNSMAV
460 470 480 490 500
SNEHFHTALG NSNPSALRET VVEVPNVSWE DIGGLENVKR ELQETVQYPV
510 520 530 540 550
EHPEKFEKFG MSPSKGVLFY GPPGCGKTLL AKAIANECQA NFISVKGPEL
560 570 580 590 600
LTMWFGESEA NVREIFDKAR QSAPCVLFFD ELDSIATQRG NSAGDAGGAA
610 620 630 640 650
DRVLNQLLTE MDGMNAKKTV FIIGATNRPD IIDSALLRPG RLDQLIYIPL
660 670 680 690 700
PDEDSRLNIF KACLRKSPVA KDVDVTALAK YTQGFSGADI TEICQRACKY
710 720 730 740 750
AIRENIEKDI ENERRRSQNP EAMEEDMVDD EVSEIRAAHF EESMKYARRS
760 770 780 790 800
VSDADIRKYQ AFAQTLQQSR GFGSEFRFDS TAGVGRTTGV AAADPFATSA
810
AAADDDDLYS
Length:810
Mass (Da):89,958
Last modified:February 1, 2003 - v2
Checksum:i1E8D08C6C5FA5F68
GO

Sequence cautioni

The sequence CAB83290 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162751 Genomic DNA Translation: CAB83290.1 Sequence problems.
CP002688 Genomic DNA Translation: AED90587.1
AK117125 mRNA Translation: BAC41803.1
AK118571 mRNA Translation: BAC43171.1
BT006485 mRNA Translation: AAP21293.1
RefSeqiNP_568114.1, NM_120412.3
UniGeneiAt.33291

Genome annotation databases

EnsemblPlantsiAT5G03340.1; AT5G03340.1; AT5G03340
GeneIDi831870
GrameneiAT5G03340.1; AT5G03340.1; AT5G03340
KEGGiath:AT5G03340

Similar proteinsi

Entry informationi

Entry nameiCD48E_ARATH
AccessioniPrimary (citable) accession number: Q9LZF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: February 1, 2003
Last modified: May 23, 2018
This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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