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Q9LZ86

- P2C66_ARATH

UniProt

Q9LZ86 - P2C66_ARATH

Protein

Probable protein phosphatase 2C 66

Gene

PLL2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 1 (01 Oct 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 magnesium or manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi282 – 2821Manganese 1By similarity
    Metal bindingi282 – 2821Manganese 2By similarity
    Metal bindingi283 – 2831Manganese 1; via carbonyl oxygenBy similarity
    Metal bindingi593 – 5931Manganese 2By similarity
    Metal bindingi656 – 6561Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Magnesium, Manganese, Metal-binding

    Enzyme and pathway databases

    BioCyciARA:AT5G02400-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable protein phosphatase 2C 66 (EC:3.1.3.16)
    Short name:
    AtPP2C66
    Alternative name(s):
    Protein POLTERGEIST-LIKE 2
    Protein phosphatase 2C PLL2
    Short name:
    PP2C PLL2
    Gene namesi
    Name:PLL2
    Ordered Locus Names:At5g02400
    ORF Names:T1E22.160
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 5

    Organism-specific databases

    TAIRiAT5G02400.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Disruption phenotypei

    No visible phenotype.1 Publication

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 674674Probable protein phosphatase 2C 66PRO_0000301260Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei125 – 1251PhosphoserineBy similarity

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    PRIDEiQ9LZ86.

    Expressioni

    Tissue specificityi

    Expressed at low level in seedlings, roots, leaves, stems, young inflorescences, flowers and siliques.1 Publication

    Gene expression databases

    GenevestigatoriQ9LZ86.

    Interactioni

    Protein-protein interaction databases

    STRINGi3702.AT5G02400.1-P.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9LZ86.
    SMRiQ9LZ86. Positions 396-669.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini322 – 637316PP2C-likeAdd
    BLAST

    Domaini

    The conserved PP2C phosphatase domain (244-663) is interrupted by an insertion of approximately 100 amino acids.

    Sequence similaritiesi

    Belongs to the PP2C family.Curated
    Contains 1 PP2C-like domain.Curated

    Phylogenomic databases

    eggNOGiNOG289757.
    HOGENOMiHOG000239375.
    InParanoidiQ9LZ86.
    OMAiCAVENDR.
    PhylomeDBiQ9LZ86.

    Family and domain databases

    Gene3Di3.60.40.10. 3 hits.
    InterProiIPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view]
    PANTHERiPTHR13832. PTHR13832. 1 hit.
    PfamiPF00481. PP2C. 1 hit.
    [Graphical view]
    SMARTiSM00332. PP2Cc. 1 hit.
    [Graphical view]
    SUPFAMiSSF81606. SSF81606. 3 hits.

    Sequencei

    Sequence statusi: Complete.

    Q9LZ86-1 [UniParc]FASTAAdd to Basket

    « Hide

    MGNGVTTLTG CCTGTLAGEI SRRYDVSLVH DGLGHSFCYI RPDLPGVVLP    50
    SPESPLRSDH IQETTFRSIS GASVSANPST ALSGALSSDS DCPYSSAVSA 100
    SAFESSGNFA SLPLQPVPRG STWQSGPIVN ESGLGSAPFE RRFLSGPIES 150
    GLYSGPIEST KKTEKEKPKK IRKKPKSKKN FLTFKTLFAN LISNNNKPRL 200
    KKSVIEPING SDSSDSGRLH HEPVITSSRS NENPKSDLEE EDEKQSMNSV 250
    LDVQWAQGKA GEDRVHVVVS EDNGWVFVGI YDGFSGPDAP DYLLNNLYTA 300
    VQKELNGLLW NDEKLRSLGE NGMTKTGKCS DEEDPESGKE NCPVINNDDA 350
    VASGARNQAK SLKWRCEWEK KSNNKTKSDN RCDQKGSNST TTNHKDVLKA 400
    LLQALRKTED AYLELADQMV KENPELALMG SCVLVTLMKG EDVYVMNVGD 450
    SRAVLGRKPN LATGRKRQKE LERIREDSSL EDKEILMNGA MRNTLVPLQL 500
    NMEHSTRIEE EVRRIKKEHP DDDCAVENDR VKGYLKVTRA FGAGFLKQPK 550
    WNDALLEMFR IDYIGTSPYI TCSPSLCHHK LTSRDKFLIL SSDGLYEYFS 600
    NQEAIFEVES FISAFPEGDP AQHLIQEVLL RAANKFGMDF HELLEIPQGD 650
    RRRYHDDVSV IVISLEGRIW RSSM 674
    Length:674
    Mass (Da):74,838
    Last modified:October 1, 2000 - v1
    Checksum:iCA2DE97E69791B0D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL162874 Genomic DNA. Translation: CAB85545.1.
    CP002688 Genomic DNA. Translation: AED90468.1.
    PIRiT48261.
    RefSeqiNP_195860.1. NM_120318.1.
    UniGeneiAt.54686.

    Genome annotation databases

    EnsemblPlantsiAT5G02400.1; AT5G02400.1; AT5G02400.
    GeneIDi830937.
    KEGGiath:AT5G02400.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL162874 Genomic DNA. Translation: CAB85545.1 .
    CP002688 Genomic DNA. Translation: AED90468.1 .
    PIRi T48261.
    RefSeqi NP_195860.1. NM_120318.1.
    UniGenei At.54686.

    3D structure databases

    ProteinModelPortali Q9LZ86.
    SMRi Q9LZ86. Positions 396-669.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 3702.AT5G02400.1-P.

    Proteomic databases

    PRIDEi Q9LZ86.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT5G02400.1 ; AT5G02400.1 ; AT5G02400 .
    GeneIDi 830937.
    KEGGi ath:AT5G02400.

    Organism-specific databases

    TAIRi AT5G02400.

    Phylogenomic databases

    eggNOGi NOG289757.
    HOGENOMi HOG000239375.
    InParanoidi Q9LZ86.
    OMAi CAVENDR.
    PhylomeDBi Q9LZ86.

    Enzyme and pathway databases

    BioCyci ARA:AT5G02400-MONOMER.

    Gene expression databases

    Genevestigatori Q9LZ86.

    Family and domain databases

    Gene3Di 3.60.40.10. 3 hits.
    InterProi IPR001932. PP2C-like_dom.
    IPR015655. Protein_Pase_2C.
    [Graphical view ]
    PANTHERi PTHR13832. PTHR13832. 1 hit.
    Pfami PF00481. PP2C. 1 hit.
    [Graphical view ]
    SMARTi SM00332. PP2Cc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81606. SSF81606. 3 hits.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
      Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.
      , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
      Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    2. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    3. "POL and related phosphatases are dosage-sensitive regulators of meristem and organ development in Arabidopsis."
      Song S.-K., Clark S.E.
      Dev. Biol. 285:272-284(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, GENE FAMILY, NOMENCLATURE, DISRUPTION PHENOTYPE.
    4. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
      Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
      BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: GENE FAMILY, NOMENCLATURE.

    Entry informationi

    Entry nameiP2C66_ARATH
    AccessioniPrimary (citable) accession number: Q9LZ86
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 11, 2007
    Last sequence update: October 1, 2000
    Last modified: October 1, 2014
    This is version 80 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3