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Protein

Probable protein phosphatase 2C 66

Gene

PLL2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi282Manganese 1By similarity1
Metal bindingi282Manganese 2By similarity1
Metal bindingi283Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi593Manganese 2By similarity1
Metal bindingi656Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 66 (EC:3.1.3.16)
Short name:
AtPP2C66
Alternative name(s):
Protein POLTERGEIST-LIKE 2
Protein phosphatase 2C PLL2
Short name:
PP2C PLL2
Gene namesi
Name:PLL2
Ordered Locus Names:At5g02400
ORF Names:T1E22.160
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G02400.
TAIRilocus:2180152. AT5G02400.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003012601 – 674Probable protein phosphatase 2C 66Add BLAST674

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei125PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ9LZ86.
PRIDEiQ9LZ86.

Expressioni

Tissue specificityi

Expressed at low level in seedlings, roots, leaves, stems, young inflorescences, flowers and siliques.1 Publication

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G02400.1.

Structurei

3D structure databases

ProteinModelPortaliQ9LZ86.
SMRiQ9LZ86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini244 – 665PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST422

Domaini

The conserved PP2C phosphatase domain (244-663) is interrupted by an insertion of approximately 100 amino acids.

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0700. Eukaryota.
COG0631. LUCA.
HOGENOMiHOG000239375.
InParanoidiQ9LZ86.
OMAiNLYTAVQ.
OrthoDBiEOG093601X0.
PhylomeDBiQ9LZ86.

Family and domain databases

CDDicd00143. PP2Cc. 1 hit.
Gene3Di3.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR015655. PP2C.
IPR036457. PPM-type_dom_sf.
IPR001932. PPM-type_phosphatase_dom.
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiView protein in Pfam
PF00481. PP2C. 1 hit.
SMARTiView protein in SMART
SM00332. PP2Cc. 1 hit.
SUPFAMiSSF81606. SSF81606. 3 hits.
PROSITEiView protein in PROSITE
PS51746. PPM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9LZ86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNGVTTLTG CCTGTLAGEI SRRYDVSLVH DGLGHSFCYI RPDLPGVVLP
60 70 80 90 100
SPESPLRSDH IQETTFRSIS GASVSANPST ALSGALSSDS DCPYSSAVSA
110 120 130 140 150
SAFESSGNFA SLPLQPVPRG STWQSGPIVN ESGLGSAPFE RRFLSGPIES
160 170 180 190 200
GLYSGPIEST KKTEKEKPKK IRKKPKSKKN FLTFKTLFAN LISNNNKPRL
210 220 230 240 250
KKSVIEPING SDSSDSGRLH HEPVITSSRS NENPKSDLEE EDEKQSMNSV
260 270 280 290 300
LDVQWAQGKA GEDRVHVVVS EDNGWVFVGI YDGFSGPDAP DYLLNNLYTA
310 320 330 340 350
VQKELNGLLW NDEKLRSLGE NGMTKTGKCS DEEDPESGKE NCPVINNDDA
360 370 380 390 400
VASGARNQAK SLKWRCEWEK KSNNKTKSDN RCDQKGSNST TTNHKDVLKA
410 420 430 440 450
LLQALRKTED AYLELADQMV KENPELALMG SCVLVTLMKG EDVYVMNVGD
460 470 480 490 500
SRAVLGRKPN LATGRKRQKE LERIREDSSL EDKEILMNGA MRNTLVPLQL
510 520 530 540 550
NMEHSTRIEE EVRRIKKEHP DDDCAVENDR VKGYLKVTRA FGAGFLKQPK
560 570 580 590 600
WNDALLEMFR IDYIGTSPYI TCSPSLCHHK LTSRDKFLIL SSDGLYEYFS
610 620 630 640 650
NQEAIFEVES FISAFPEGDP AQHLIQEVLL RAANKFGMDF HELLEIPQGD
660 670
RRRYHDDVSV IVISLEGRIW RSSM
Length:674
Mass (Da):74,838
Last modified:October 1, 2000 - v1
Checksum:iCA2DE97E69791B0D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL162874 Genomic DNA. Translation: CAB85545.1.
CP002688 Genomic DNA. Translation: AED90468.1.
PIRiT48261.
RefSeqiNP_195860.1. NM_120318.2.

Genome annotation databases

EnsemblPlantsiAT5G02400.1; AT5G02400.1; AT5G02400.
GeneIDi830937.
GrameneiAT5G02400.1; AT5G02400.1; AT5G02400.
KEGGiath:AT5G02400.

Similar proteinsi

Entry informationi

Entry nameiP2C66_ARATH
AccessioniPrimary (citable) accession number: Q9LZ86
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: October 1, 2000
Last modified: October 25, 2017
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families