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Q9LZ06 (GSTL3_ARATH) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutathione S-transferase L3

Short name=AtGSTL3
EC=2.5.1.18
Alternative name(s):
GST class-lambda member 3
Gene names
Name:GSTL3
Ordered Locus Names:At5g02790
ORF Names:F9G14.100
OrganismArabidopsis thaliana (Mouse-ear cress) [Reference proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis

Protein attributes

Sequence length235 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Catalyzes the glutathione-dependent reduction of S-glutathionylquercetin to quercetin. Ref.5

Catalytic activity

RX + glutathione = HX + R-S-glutathione.

Subcellular location

Cytoplasmcytosol Probable.

Sequence similarities

Belongs to the GST superfamily. Lambda family.

Contains 1 GST C-terminal domain.

Contains 1 GST N-terminal domain.

Ontologies

Keywords
   Biological processDetoxification
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processresponse to cadmium ion

Inferred from expression pattern PubMed 16502469. Source: TAIR

response to toxic substance

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentcytosol

Inferred from direct assay PubMed 21166475. Source: TAIR

   Molecular_functionglutathione transferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 235235Glutathione S-transferase L3
PRO_0000413579

Regions

Domain27 – 10882GST N-terminal
Domain86 – 230145GST C-terminal
Region37 – 382Glutathione binding By similarity
Region65 – 662Glutathione binding By similarity
Region79 – 802Glutathione binding By similarity
Region92 – 932Glutathione binding By similarity

Experimental info

Sequence conflict1891N → D in AAM61679. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Q9LZ06 [UniParc].

Last modified October 1, 2000. Version 1.
Checksum: 52713E37176B2EB6

FASTA23527,090
        10         20         30         40         50         60 
MAPSFIFVED RPAPLDATSD PPSLFDGTTR LYTSYVCPFA QRVWITRNFK GLQEKIKLVP 

        70         80         90        100        110        120 
LDLGNRPAWY KEKVYPENKV PALEHNGKII GESLDLIKYL DNTFEGPSLY PEDHAKREFG 

       130        140        150        160        170        180 
DELLKYTDTF VKTMYVSLKG DPSKETAPVL DYLENALYKF DDGPFFLGQL SLVDIAYIPF 

       190        200        210        220        230 
IERFQTVLNE LFKCDITAER PKLSAWIEEI NKSDGYAQTK MDPKEIVEVF KKKFM 

« Hide

References

« Hide 'large scale' references
[1]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
[2]The Arabidopsis Information Resource (TAIR)
Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: cv. Columbia.
[3]"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs."
Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K. expand/collapse author list , Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y., Shinozaki K.
Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: cv. Columbia.
[4]"Full-length cDNA from Arabidopsis thaliana."
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[5]"Roles for stress-inducible lambda glutathione transferases in flavonoid metabolism in plants as identified by ligand fishing."
Dixon D.P., Edwards R.
J. Biol. Chem. 285:36322-36329(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: FUNCTION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL162973 Genomic DNA. Translation: CAB86033.1.
CP002688 Genomic DNA. Translation: AED90518.1.
AY140069 mRNA. Translation: AAM98210.1.
BT002166 mRNA. Translation: AAN72177.1.
AK227162 mRNA. Translation: BAE99204.1.
AY085126 mRNA. Translation: AAM61679.1.
PIRT48300.
RefSeqNP_195899.1. NM_120357.5.
UniGeneAt.33363.

3D structure databases

ProteinModelPortalQ9LZ06.
SMRQ9LZ06. Positions 38-228.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING3702.AT5G02790.1-P.

Proteomic databases

PRIDEQ9LZ06.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsAT5G02790.1; AT5G02790.1; AT5G02790.
GeneID831798.
KEGGath:AT5G02790.

Organism-specific databases

TAIRAT5G02790.

Phylogenomic databases

eggNOGCOG0625.
HOGENOMHOG000239968.
InParanoidQ9LZ06.
KOK00799.
OMACDITAER.
PhylomeDBQ9LZ06.

Gene expression databases

GenevestigatorQ9LZ06.

Family and domain databases

Gene3D1.20.1050.10. 1 hit.
3.40.30.10. 1 hit.
InterProIPR010987. Glutathione-S-Trfase_C-like.
IPR004045. Glutathione_S-Trfase_N.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF13417. GST_N_3. 1 hit.
[Graphical view]
SUPFAMSSF47616. SSF47616. 1 hit.
SSF52833. SSF52833. 1 hit.
PROSITEPS50405. GST_CTER. 1 hit.
PS50404. GST_NTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSTL3_ARATH
AccessionPrimary (citable) accession number: Q9LZ06
Secondary accession number(s): Q8LF01
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2011
Last sequence update: October 1, 2000
Last modified: May 14, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names